Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway VS Viswanathan, MJ Ryan, HD Dhruv, S Gill, OM Eichhoff, ... Nature 547 (7664), 453-457, 2017 | 1487 | 2017 |
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition MJ Hangauer, VS Viswanathan, MJ Ryan, D Bole, JK Eaton, A Matov, ... Nature 551 (7679), 247-250, 2017 | 1300 | 2017 |
Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks JC Chen, MJ Alvarez, F Talos, H Dhruv, GE Rieckhof, A Iyer, KL Diefes, ... Cell 159 (2), 402-414, 2014 | 211 | 2014 |
MicroRNA‐328 is associated with (non‐small) cell lung cancer (NSCLC) brain metastasis and mediates NSCLC migration S Arora, AR Ranade, NL Tran, S Nasser, S Sridhar, RL Korn, JTD Ross, ... International journal of cancer 129 (11), 2621-2631, 2011 | 206 | 2011 |
Genomic and phenotypic characterization of a broad panel of patient-derived xenografts reflects the diversity of glioblastoma RA Vaubel, S Tian, D Remonde, MA Schroeder, AC Mladek, GJ Kitange, ... Clinical Cancer Research 26 (5), 1094-1104, 2020 | 153 | 2020 |
Intravenous delivery of camptothecin-loaded PLGA nanoparticles for the treatment of intracranial glioma KT Householder, DM DiPerna, EP Chung, GM Wohlleb, HD Dhruv, ... International journal of pharmaceutics 479 (2), 374-380, 2015 | 140 | 2015 |
Evaluation of pre-analytical factors affecting plasma DNA analysis H Markus, T Contente-Cuomo, M Farooq, WS Liang, MJ Borad, ... Scientific reports 8 (1), 7375, 2018 | 136 | 2018 |
Phase 0 trial of AZD1775 in first-recurrence glioblastoma patients N Sanai, J Li, J Boerner, K Stark, J Wu, S Kim, A Derogatis, S Mehta, ... Clinical Cancer Research 24 (16), 3820-3828, 2018 | 82 | 2018 |
Reciprocal activation of transcription factors underlies the dichotomy between proliferation and invasion of glioma cells HD Dhruv, WS McDonough Winslow, B Armstrong, S Tuncali, ... PloS one 8 (8), e72134, 2013 | 67 | 2013 |
Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma RS McNeill, DA Canoutas, TJ Stuhlmiller, HD Dhruv, DM Irvin, RE Bash, ... Neuro-oncology 19 (11), 1469-1480, 2017 | 60 | 2017 |
EGFRvIII–Stat5 signaling enhances glioblastoma cell migration and survival A Roos, HD Dhruv, S Peng, LJ Inge, S Tuncali, M Pineda, N Millard, ... Molecular Cancer Research 16 (7), 1185-1195, 2018 | 57 | 2018 |
TROY (TNFRSF19) promotes glioblastoma survival signaling and therapeutic resistance JC Loftus, H Dhruv, S Tuncali, J Kloss, Z Yang, CA Schumacher, B Cao, ... Molecular Cancer Research 11 (8), 865-874, 2013 | 53 | 2013 |
Integrated genomic analysis of survival outliers in glioblastoma S Peng, H Dhruv, B Armstrong, B Salhia, C Legendre, J Kiefer, J Parks, ... Neuro-oncology 19 (6), 833-844, 2017 | 45 | 2017 |
Bioresponsive Copolymers of Poly(N-isopropylacrylamide) with Enzyme-Dependent Lower Critical Solution Temperatures DJ Overstreet, HD Dhruv, BL Vernon Biomacromolecules 11 (5), 1154-1159, 2010 | 40 | 2010 |
Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells A Roos, HD Dhruv, IT Mathews, LJ Inge, S Tuncali, LK Hartman, D Chow, ... Oncotarget 8 (7), 12234, 2017 | 35 | 2017 |
Differential response of glioma stem cells to arsenic trioxide therapy is regulated by MNK1 and mRNA translation JB Bell, F Eckerdt, HD Dhruv, D Finlay, S Peng, S Kim, B Kroczynska, ... Molecular Cancer Research 16 (1), 32-46, 2018 | 33 | 2018 |
Hepatitis C virus infection and cholangiocarcinoma: an insight into epidemiologic evidences and hypothetical mechanisms of oncogenesis MC Navas, S Glaser, H Dhruv, S Celinski, G Alpini, F Meng The American Journal of Pathology 189 (6), 1122-1132, 2019 | 31 | 2019 |
A novel interaction between Pyk2 and MAP4K4 is integrated with glioma cell migration JC Loftus, Z Yang, J Kloss, H Dhruv, NL Tran, DL Riggs Journal of Signal Transduction 2013 (1), 956580, 2013 | 30 | 2013 |
Structural basis and targeting of the interaction between fibroblast growth factor-inducible 14 and tumor necrosis factor-like weak inducer of apoptosis H Dhruv, JC Loftus, P Narang, JL Petit, M Fameree, J Burton, G Tchegho, ... Journal of Biological Chemistry 288 (45), 32261-32276, 2013 | 27 | 2013 |
Protein insertion and patterning of PEG bearing Langmuir monolayers H Dhruv, R Pepalla, M Taveras, DW Britt Biotechnology progress 22 (1), 150-155, 2006 | 26 | 2006 |