| The transcription factor NRSF contributes to epileptogenesis by selective repression of a subset of target genes S McClelland, GP Brennan, C Dubé, S Rajpara, S Iyer, C Richichi, ... Elife 3, e01267, 2014 | 141 | 2014 |
| Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis RC McKiernan, EM Jimenez-Mateos, I Bray, T Engel, GP Brennan, T Sano, ... PloS one 7 (5), e35921, 2012 | 139 | 2012 |
| MicroRNAs as regulators of brain function and targets for treatment of epilepsy GP Brennan, DC Henshall Nature Reviews Neurology 16 (9), 506-519, 2020 | 122 | 2020 |
| Dual and opposing roles of microRNA-124 in epilepsy are mediated through inflammatory and NRSF-dependent gene networks GP Brennan, D Dey, Y Chen, KP Patterson, EJ Magnetta, AM Hall, ... Cell reports 14 (10), 2402-2412, 2016 | 116 | 2016 |
| Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy R Raoof, S Bauer, H El Naggar, NMC Connolly, GP Brennan, E Brindley, ... EBioMedicine 38, 127-141, 2018 | 101 | 2018 |
| A microRNA‐129‐5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses M Rajman, F Metge, R Fiore, S Khudayberdiev, A Aksoy‐Aksel, S Bicker, ... The EMBO journal 36 (12), 1770-1787, 2017 | 97 | 2017 |
| microRNAs in the pathophysiology of epilepsy GP Brennan, DC Henshall Neuroscience letters 667, 47-52, 2018 | 74 | 2018 |
| Rapid, coordinate inflammatory responses after experimental febrile status epilepticus: implications for epileptogenesis KP Patterson, GP Brennan, M Curran, E Kinney-Lang, C Dubé, F Rashid, ... Eneuro 2 (5), 2015 | 62 | 2015 |
| Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels in Epilepsy GP Brennan, TZ Baram, NP Poolos Cold Spring Harbor Perspectives in Medicine, 2016 | 61 | 2016 |
| Enduring memory impairments provoked by developmental febrile seizures are mediated by functional and structural effects of neuronal restrictive silencing factor KP Patterson, JM Barry, MM Curran, A Singh-Taylor, G Brennan, ... Journal of Neuroscience 37 (14), 3799-3812, 2017 | 58 | 2017 |
| A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy MT Venø, CR Reschke, G Morris, NMC Connolly, J Su, Y Yan, T Engel, ... Proceedings of the National Academy of Sciences 117 (27), 15977-15988, 2020 | 53 | 2020 |
| Genome-wide microRNA profiling of plasma from three different animal models identifies biomarkers of temporal lobe epilepsy GP Brennan, S Bauer, T Engel, EM Jimenez-Mateos, F Del Gallo, ... Neurobiology of Disease 144, 105048, 2020 | 49 | 2020 |
| Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo GP Brennan, EM Jimenez-Mateos, RC McKiernan, T Engel, G Tzivion, ... PloS one 8 (1), e54491, 2013 | 48 | 2013 |
| A calcium-sensitive feed-forward loop regulating the expression of the ATP-gated purinergic P2X7 receptor via specificity protein 1 and microRNA-22 T Engel, GP Brennan, A Sanz-Rodriguez, M Alves, E Beamer, O Watters, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864 (2), 255-266, 2017 | 42 | 2017 |
| Regulatory Mechanisms of the RNA Modification m6A and Significance in Brain Function in Health and Disease J Mathoux, DC Henshall, GP Brennan Frontiers in cellular neuroscience 15, 671932, 2021 | 39 | 2021 |
| Epigenetic principles underlying epileptogenesis and epilepsy syndromes K Conboy, DC Henshall, GP Brennan Neurobiology of disease 148, 105179, 2021 | 34 | 2021 |
| Antagonizing increased miR-135a levels at the chronic stage of experimental TLE reduces spontaneous recurrent seizures VR Vangoor, CR Reschke, K Senthilkumar, LL Van De Haar, M De Wit, ... Journal of Neuroscience 39 (26), 5064-5079, 2019 | 34 | 2019 |
| CHD2-related CNS pathologies MM Wilson, DC Henshall, SM Byrne, GP Brennan International journal of molecular sciences 22 (2), 588, 2021 | 31 | 2021 |
| Systemic delivery of antagomirs during blood-brain barrier disruption is disease-modifying in experimental epilepsy CR Reschke, LFA Silva, VR Vangoor, M Rosso, B David, BL Cavanagh, ... Molecular Therapy 29 (6), 2041-2052, 2021 | 28 | 2021 |
| Spatiotemporal progression of ubiquitin-proteasome system inhibition after status epilepticus suggests protective adaptation against hippocampal injury T Engel, J Martinez-Villarreal, C Henke, EM Jimenez-Mateos, ... Molecular neurodegeneration 12, 1-17, 2017 | 28 | 2017 |