| Loss of autophagy in the central nervous system causes neurodegeneration in mice M Komatsu, S Waguri, T Chiba, S Murata, J Iwata, I Tanida, T Ueno, ... Nature 441 (7095), 880-884, 2006 | 4069 | 2006 |
| Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice M Komatsu, S Waguri, T Ueno, J Iwata, S Murata, I Tanida, J Ezaki, ... The Journal of cell biology 169 (3), 425-434, 2005 | 2747 | 2005 |
| Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice M Komatsu, S Waguri, M Koike, Y Sou, T Ueno, T Hara, N Mizushima, ... Cell 131 (6), 1149-1163, 2007 | 2382 | 2007 |
| Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration M Komatsu, QJ Wang, GR Holstein, VL Friedrich Jr, J Iwata, E Kominami, ... Proceedings of the National Academy of Sciences 104 (36), 14489-14494, 2007 | 667 | 2007 |
| The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice Y Sou, S Waguri, J Iwata, T Ueno, T Fujimura, T Hara, N Sawada, ... Molecular biology of the cell 19 (11), 4762-4775, 2008 | 546 | 2008 |
| Liver autophagy contributes to the maintenance of blood glucose and amino acid levels J Ezaki, N Matsumoto, M Takeda-Ezaki, M Komatsu, K Takahashi, ... Autophagy 7 (7), 727-736, 2011 | 325 | 2011 |
| Excess peroxisomes are degraded by autophagic machinery in mammals J Iwata, J Ezaki, M Komatsu, S Yokota, T Ueno, I Tanida, T Chiba, ... Journal of Biological Chemistry 281 (7), 4035-4041, 2006 | 296 | 2006 |
| Modulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice J Iwata, JG Hacia, A Suzuki, PA Sanchez-Lara, M Urata, Y Chai The Journal of clinical investigation 122 (3), 873-885, 2012 | 130 | 2012 |
| The mechanism of TGF‐β signaling during palate development J Iwata, C Parada, Y Chai Oral diseases 17 (8), 733-744, 2011 | 125 | 2011 |
| Cathepsin E prevents tumor growth and metastasis by catalyzing the proteolytic release of soluble TRAIL from tumor cell surface T Kawakubo, K Okamoto, J Iwata, M Shin, Y Okamoto, A Yasukochi, ... Cancer research 67 (22), 10869-10878, 2007 | 99 | 2007 |
| Smad4-Irf6 genetic interaction and TGFβ-mediated IRF6 signaling cascade are crucial for palatal fusion in mice J Iwata, A Suzuki, RC Pelikan, TV Ho, PA Sanchez-Lara, M Urata, ... Development 140 (6), 1220-1230, 2013 | 95 | 2013 |
| The FaceBase Consortium: a comprehensive program to facilitate craniofacial research H Hochheiser, BJ Aronow, K Artinger, TH Beaty, JF Brinkley, Y Chai, ... Developmental biology 355 (2), 175-182, 2011 | 88 | 2011 |
| WNT/β-catenin signaling regulates multiple steps of myogenesis by regulating step-specific targets A Suzuki, RC Pelikan, J Iwata Molecular and cellular biology, 2015 | 86 | 2015 |
| Transforming Growth Factor-β Regulates Basal Transcriptional Regulatory Machinery to Control Cell Proliferation and Differentiation in Cranial Neural Crest-derived … J Iwata, R Hosokawa, PA Sanchez-Lara, M Urata, H Slavkin, Y Chai Journal of Biological Chemistry 285 (7), 4975-4982, 2010 | 85 | 2010 |
| TGF-β mediated FGF10 signaling in cranial neural crest cells controls development of myogenic progenitor cells through tissue–tissue interactions during tongue morphogenesis R Hosokawa, K Oka, T Yamaza, J Iwata, M Urata, X Xu, P Bringas Jr, ... Developmental biology 341 (1), 186-195, 2010 | 84 | 2010 |
| Molecular mechanisms of midfacial developmental defects A Suzuki, DR Sangani, A Ansari, J Iwata Developmental Dynamics 245 (3), 276-293, 2016 | 73 | 2016 |
| CTGF mediates Smad-dependent transforming growth factor β signaling to regulate mesenchymal cell proliferation during palate development C Parada, J Li, J Iwata, A Suzuki, Y Chai Molecular and cellular biology, 2013 | 72 | 2013 |
| Fibroblast growth factor 9 (FGF9)-pituitary homeobox 2 (PITX2) pathway mediates transforming growth factor β (TGFβ) signaling to regulate cell proliferation in palatal … J Iwata, L Tung, M Urata, JG Hacia, R Pelikan, A Suzuki, L Ramenzoni, ... Journal of Biological Chemistry 287 (4), 2353-2363, 2012 | 64 | 2012 |
| Mice with Tak1 deficiency in neural crest lineage exhibit cleft palate associated with abnormal tongue development Z Song, C Liu, J Iwata, S Gu, A Suzuki, C Sun, W He, R Shu, L Li, Y Chai, ... Journal of Biological Chemistry 288 (15), 10440-10450, 2013 | 61 | 2013 |
| Role of metabolism in bone development and homeostasis A Suzuki, M Minamide, C Iwaya, K Ogata, J Iwata International journal of molecular sciences 21 (23), 8992, 2020 | 59 | 2020 |
Noboru MizushimaThe University of TokyoVerified email at m.u-tokyo.ac.jp