| Synthesis of 4 (1H)-quinolones by thermolysis of arylaminomethylene Meldrum's acid derivatives R Cassis, R Tapia, JA Valderrama Synthetic Communications 15 (2), 125-133, 1985 | 145 | 1985 |
| Biological evaluation of donor-acceptor aminonaphthoquinones as antitumor agents J Benites, JA Valderrama, K Bettega, RC Pedrosa, PB Calderon, J Verrax European journal of medicinal chemistry 45 (12), 6052-6057, 2010 | 138 | 2010 |
| Studies on quinones. Part 44: Novel angucyclinone N-heterocyclic analogues endowed with antitumoral activity JA Valderrama, P Colonelli, D Vásquez, MF González, JA Rodríguez, ... Bioorganic & medicinal chemistry 16 (24), 10172-10181, 2008 | 107 | 2008 |
| Studies on quinones. Part 45: Novel 7-aminoisoquinoline-5, 8-quinone derivatives with antitumor properties on cancer cell lines JA Valderrama, JA Ibacache, V Arancibia, J Rodriguez, C Theoduloz Bioorganic & medicinal chemistry 17 (7), 2894-2901, 2009 | 82 | 2009 |
| Synthesis and antiprotozoal activity of naphthofuranquinones and naphthothiophenequinones containing a fused thiazole ring RA Tapia, L Alegria, CD Pessoa, C Salas, MJ Cortés, JA Valderrama, ... Bioorganic & medicinal chemistry 11 (10), 2175-2182, 2003 | 67 | 2003 |
| Nitric acid on silica gel: A useful nitrating reagent for activated aromatic compounds R Tapia, G Torres, JA Valderrama Synthetic Communications 16 (6), 681-687, 1986 | 60 | 1986 |
| Studies on quinones. Part 46. Synthesis and in vitro antitumor evaluation of aminopyrimidoisoquinolinequinones D Vásquez, JA Rodríguez, C Theoduloz, PB Calderon, JA Valderrama European journal of medicinal chemistry 45 (11), 5234-5242, 2010 | 55 | 2010 |
| Studies on quinones. Part 41: Synthesis and cytotoxicity of isoquinoline-containing polycyclic quinones JA Valderrama, MF González, D Pessoa-Mahana, RA Tapia, H Fillion, ... Bioorganic & medicinal chemistry 14 (14), 5003-5011, 2006 | 55 | 2006 |
| Synthesis of 3-carboxycoumarins from o-methoxybenzylidene Meldrum's acid derivatives V Armstrong, O Soto, JA Valderrama, R Tapia Synthetic Communications 18 (7), 717-725, 1988 | 55 | 1988 |
| DNA Damage and Inhibition of Akt Pathway in MCF‐7 Cells and Ehrlich Tumor in Mice Treated with 1, 4‐Naphthoquinones in Combination with Ascorbate F Ourique, MR Kviecinski, KB Felipe, JFG Correia, MS Farias, LS Castro, ... Oxidative medicine and cellular longevity 2015 (1), 495305, 2015 | 53 | 2015 |
| Studies on quinones. Part 38: Synthesis and leishmanicidal activity of sesquiterpene 1, 4-quinones JA Valderrama, J Benites, M Cortés, H Pessoa-Mahana, E Prina, ... Bioorganic & medicinal chemistry 11 (22), 4713-4718, 2003 | 50 | 2003 |
| Synthesis and in vitro antiprotozoal activity of thiophene ring-containing quinones J Valderrama, A Fournet, C Valderrama, S Bastias, C Astudillo, ... Chemical and pharmaceutical bulletin 47 (9), 1221-1226, 1999 | 48 | 1999 |
| The solar-chemical photo-Friedel–Crafts heteroacylation of 1, 4-quinones J Benites, D Rios, P Díaz, JA Valderrama Tetrahedron Letters 52 (5), 609-611, 2011 | 46 | 2011 |
| Inhibition of cell proliferation and migration by oxidative stress from ascorbate-driven juglone redox cycling in human bladder-derived T24 cells MR Kviecinski, RC Pedrosa, KB Felipe, MS Farias, C Glorieux, ... Biochemical and biophysical research communications 421 (2), 268-273, 2012 | 43 | 2012 |
| Studies on quinones. Part 42: Synthesis of furylquinone and hydroquinones with antiproliferative activity against human tumor cell lines J Benites, JA Valderrama, F Rivera, L Rojo, N Campos, M Pedro, ... Bioorganic & medicinal chemistry 16 (2), 862-868, 2008 | 43 | 2008 |
| Studies on quinones. Part 47. Synthesis of novel phenylaminophenanthridinequinones as potential antitumor agents JA Valderrama, A Ibacache, JA Rodriguez, C Theoduloz, J Benites European journal of medicinal chemistry 46 (8), 3398-3409, 2011 | 42 | 2011 |
| Synthesis of potential anticancer 1-(1H-Indol-3-yl) isoquinolines by silver nitrate mediated tandem reactions of 2-alkynylbenzaldehyde azines and indoles YH Zhao, Y Luo, Y Zhu, H Wang, H Zhou, H Tan, Z Zhou, YC Ma, W Xie, ... Synlett 29 (06), 773-778, 2018 | 40 | 2018 |
| Synthesis and in Vitro Cytotoxic Evaluation of Aminoquinones Structurally Related to Marine Isoquinolinequinones V Delgado, A Ibacache, C Theoduloz, JA Valderrama Molecules 17 (6), 7042-7056, 2012 | 40 | 2012 |
| Solvent-free synthesis of 6-arylbenzimidazo [1, 2-c] quinazolines under microwave irradiation H Pessoa-Mahana, CD Pessoa-Mahana, R Salazar, JA Valderrama, ... Synthesis 2004 (03), 436-440, 2004 | 40 | 2004 |
| Studies on Quinones. Part 30. Synthesis of Benzo[b]thiophene-4, 7-Quinones JA Valderrama, C Valderrama Synthetic communications 27 (12), 2143-2157, 1997 | 39 | 1997 |