Current approaches in CRISPR-Cas9 mediated gene editing for biomedical and therapeutic applications G Bhattacharjee, N Gohil, K Khambhati, I Mani, R Maurya, JK Karapurkar, ... Journal of Controlled Release 343, 703-723, 2022 | 46 | 2022 |
Phage engineering and phage‐assisted CRISPR‐Cas delivery to combat multidrug‐resistant pathogens K Khambhati, G Bhattacharjee, N Gohil, GK Dhanoa, AP Sagona, I Mani, ... Bioengineering & Translational Medicine 8 (2), e10381, 2023 | 28 | 2023 |
CYLD destabilizes NoxO1 protein by promoting ubiquitination and regulates prostate cancer progression S Haq, N Sarodaya, JK Karapurkar, B Suresh, JK Jo, V Singh, YS Bae, ... Cancer letters 525, 146-157, 2022 | 22 | 2022 |
The role of deubiquitinating enzymes in hematopoiesis and hematological malignancies N Sarodaya, J Karapurkar, KS Kim, SH Hong, S Ramakrishna Cancers 12 (5), 1103, 2020 | 15 | 2020 |
Dual role of deubiquitinating enzyme USP19 regulates mitotic progression and tumorigenesis by stabilizing survivin AP Chandrasekaran, A Tyagi, N Poondla, N Sarodaya, JK Karapurkar, ... Molecular Therapy 30 (11), 3414-3429, 2022 | 12 | 2022 |
Ubiquitin-specific protease 3 deubiquitinates and stabilizes Oct4 protein in human embryonic stem cells BH Rhie, AM Antao, JK Karapurkar, MS Kim, WJ Jo, S Ramakrishna, ... International Journal of Molecular Sciences 22 (11), 5584, 2021 | 12 | 2021 |
USP19 negatively regulates p53 and promotes cervical cancer progression A Tyagi, JK Karapurkar, JC Colaco, N Sarodaya, AM Antao, K Kaushal, ... Molecular Biotechnology 66 (8), 2032-2045, 2024 | 10 | 2024 |
Genome-wide screening for deubiquitinase subfamily identifies ubiquitin-specific protease 49 as a novel regulator of odontogenesis K Kaushal, EJ Kim, A Tyagi, JK Karapurkar, S Haq, HS Jung, KS Kim, ... Cell Death & Differentiation 29 (9), 1689-1704, 2022 | 10 | 2022 |
CRISPR-Cas9 based genome editing for defective gene correction in humans and other mammals JK Karapurkar, AM Antao, KS Kim, S Ramakrishna Progress in molecular biology and translational science 181, 185-229, 2021 | 10 | 2021 |
The role of the CRISPR‐Cas system in cancer drug development: Mechanisms of action and therapy AP Chandrasekaran, JK Karapurkar, HY Chung, S Ramakrishna Biotechnology Journal 17 (7), 2100468, 2022 | 9 | 2022 |
Genome-wide CRISPR/Cas9-Based screening for deubiquitinase subfamily identifies ubiquitin-specific protease 11 as a novel regulator of osteogenic differentiation K Kaushal, A Tyagi, JK Karapurkar, EJ Kim, P Tanguturi, KS Kim, HS Jung, ... International journal of molecular sciences 23 (2), 856, 2022 | 8 | 2022 |
Disease modeling and stem cell immunoengineering in regenerative medicine using CRISPR/Cas9 systems AM Antao, JK Karapurkar, DR Lee, KS Kim, S Ramakrishna Computational and Structural Biotechnology Journal 18, 3649-3665, 2020 | 8 | 2020 |
CRISPR/Cas9-based genome-wide screening of the deubiquitinase subfamily identifies USP3 as a protein stabilizer of REST blocking neuronal differentiation and promotes … JK Karapurkar, MS Kim, JC Colaco, B Suresh, N Sarodaya, DH Kim, ... Journal of Experimental & Clinical Cancer Research 42 (1), 121, 2023 | 6 | 2023 |
USP28 promotes tumorigenesis and cisplatin resistance by deubiquitinating MAST1 protein in cancer cells JK Karapurkar, JC Colaco, B Suresh, A Tyagi, SH Woo, WJ Jo, N Ko, ... Cellular and Molecular Life Sciences 81 (1), 145, 2024 | 1 | 2024 |
E3 ubiquitin ligase APC/CCdh1 regulates SLC35F2 protein turnover and inhibits cancer progression in HeLa cells JC Colaco, AP Chandrasekaran, JK Karapurkar, DAA Gowda, G Birappa, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1867 (11), 130454, 2023 | 1 | 2023 |
βTrCP1 promotes SLC35F2 protein ubiquitination and inhibits cancer progression in HeLa cells JC Colaco, AP Chandrasekaran, JK Karapurkar, G Birappa, S Rajkumar, ... Biochemical and Biophysical Research Communications 682, 27-38, 2023 | | 2023 |
Antitumor activity of AX-0085, a novel AXL kinase inhibitor: Analysis of apoptotic cell death in triple-negative breast cancer cells. MJ Choi, SH Woo, DH Kim, KK Janardhan, SI Yoon, YJ Park, J Kim, ... Journal of Clinical Oncology 41 (16_suppl), e15120-e15120, 2023 | | 2023 |
CRISPR/Cas9-based HLA immuno-engineering in human pluripotent stem cells to reduce immune rejection during cell transplantation S Ramakrishna, KJ Keshav 한양대학교, 2023 | | 2023 |
An Efficient Endothelial Cell Differentiation Protocol Using Bioactive Lipid O-Cyclic Phytosphingosine-1-Phosphate in Human Embryonic Stem Cells KS Jo, WJ Jo, AM Antao, JK Karapurkar, YJ Park, MJ Choi, ... International journal of stem cells, 0 | | |