Articles with public access mandates - Mario MilaniLearn more
Not available anywhere: 5
Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II: Structural and biological characterization
D Lecis, E Mastrangelo, L Belvisi, M Bolognesi, M Civera, F Cossu, ...
Bioorganic & medicinal chemistry 20 (22), 6709-6723, 2012
Mandates: Fondazione Cariplo
Functionalized 2, 1-benzothiazine 2, 2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase
R Cannalire, D Tarantino, A Astolfi, ML Barreca, S Sabatini, S Massari, ...
European journal of medicinal chemistry 143, 1667-1676, 2018
Mandates: Government of Italy
Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions
R Cannalire, D Tarantino, G Piorkowski, T Carletti, S Massari, T Felicetti, ...
Antiviral Research 167, 6-12, 2019
Mandates: Government of Italy
NF023 binding to XIAP‐BIR1: Searching drugs for regulation of the NF‐κB pathway
F Cossu, M Milani, S Grassi, F Malvezzi, A Corti, M Bolognesi, ...
Proteins: Structure, Function, and Bioinformatics 83 (4), 612-620, 2015
Mandates: Fondazione Cariplo
Synthesis and characterization of novel mono-and bis-guanyl hydrazones as potent and selective asic1 inhibitors able to reduce brain ischemic insult
D Gornati, R Ciccone, A Vinciguerra, S Ippati, A Pannaccione, ...
Journal of Medicinal Chemistry 64 (12), 8333-8353, 2021
Mandates: Government of Italy
Available somewhere: 19
Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug
E Mastrangelo, M Pezzullo, T De Burghgraeve, S Kaptein, B Pastorino, ...
Journal of Antimicrobial Chemotherapy 67 (8), 1884-1894, 2012
Mandates: US National Institutes of Health
FAD-binding site and NADP reactivity in human renalase: a new enzyme involved in blood pressure regulation
M Milani, F Ciriello, S Baroni, V Pandini, G Canevari, M Bolognesi, ...
Journal of molecular biology 411 (2), 463-473, 2011
Mandates: US National Institutes of Health
Targeting the BIR domains of inhibitor of apoptosis (IAP) proteins in cancer treatment
F Cossu, M Milani, E Mastrangelo, D Lecis
Computational and Structural Biotechnology Journal 17, 142-150, 2019
Mandates: Government of Italy
Glycine amidinotransferase (GATM), renal Fanconi syndrome, and kidney failure
M Reichold, ED Klootwijk, J Reinders, EA Otto, M Milani, C Broeker, ...
Journal of the American Society of Nephrology 29 (7), 1849-1858, 2018
Mandates: US National Institutes of Health, German Research Foundation, Wellcome Trust …
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor
D Tarantino, R Cannalire, E Mastrangelo, R Croci, G Querat, ML Barreca, ...
Antiviral research 134, 226-235, 2016
Mandates: Government of Italy
Ligand binding to truncated hemoglobin N from Mycobacterium tuberculosis is strongly modulated by the interplay between the distal heme pocket residues and internal water
YH Ouellet, R Daigle, P Lagüe, D Dantsker, M Milani, M Bolognesi, ...
Journal of Biological Chemistry 283 (40), 27270-27278, 2008
Mandates: US National Institutes of Health
Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant
T Giorgino, D Mattioni, A Hassan, M Milani, E Mastrangelo, A Barbiroli, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (3), 648-660, 2019
Mandates: US National Institutes of Health, Government of Italy
The activator of apoptosis Smac-DIABLO acts as a tetramer in solution
E Mastrangelo, P Vachette, F Cossu, F Malvezzi, M Bolognesi, M Milani
Biophysical Journal 108 (3), 714-723, 2015
Mandates: Fondazione Cariplo
Identification of a small molecule that compromises the structural integrity of viroplasms and rotavirus double-layered particles
C Eichwald, G De Lorenzo, EM Schraner, G Papa, M Bollati, P Swuec, ...
Journal of virology 92 (3), 10.1128/jvi. 01943-17, 2018
Mandates: Government of Italy
Gelsolin pathogenic Gly167Arg mutation promotes domain-swap dimerization of the protein
F Bonì, M Milani, A Barbiroli, L Diomede, E Mastrangelo, M de Rosa
Human molecular genetics 27 (1), 53-65, 2018
Mandates: Fondazione Telethon, Italy
Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic
F Cossu, M Milani, P Vachette, F Malvezzi, S Grassi, D Lecis, D Delia, ...
PLoS One 7 (11), e49527, 2012
Mandates: Fondazione Cariplo
Molecular basis of a novel renal amyloidosis due to N184K gelsolin variant
F Bonì, M Milani, R Porcari, A Barbiroli, S Ricagno, M De Rosa
Scientific reports 6 (1), 33463, 2016
Mandates: Fondazione Telethon, Italy
Modulation of Guanylate Cyclase Activating Protein 1 (GCAP1) Dimeric Assembly by Ca2+ or Mg2+: Hints to Understand Protein Activity
F Bonì, V Marino, C Bidoia, E Mastrangelo, A Barbiroli, D Dell’Orco, ...
Biomolecules 10 (10), 1408, 2020
Mandates: Fondazione Telethon, Italy
Missense mutations affecting Ca2+-coordination in GCAP1 lead to cone-rod dystrophies by altering protein structural and functional properties
G Dal Cortivo, V Marino, F Bonì, M Milani, D Dell'Orco
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (10), 118794, 2020
Mandates: Fondazione Telethon, Italy
Structure-based identification of a new IAP-targeting compound that induces cancer cell death inducing NF-κB pathway
F Cossu, S Camelliti, D Lecis, L Sorrentino, MT Majorini, M Milani, ...
Computational and Structural Biotechnology Journal 19, 6366-6374, 2021
Mandates: AIRC Foundation for Cancer Research in Italy
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