In vitro differentiation of embryonic stem cells into mineralized osteoblasts NI Zur Nieden, G Kempka, HJ Ahr Differentiation 71 (1), 18-27, 2003 | 440 | 2003 |
Induction of chondro-, osteo-and adipogenesis in embryonic stem cells by bone morphogenetic protein-2: effect of cofactors on differentiating lineages NI zur Nieden, G Kempka, DE Rancourt, HJ Ahr BMC developmental biology 5, 1-15, 2005 | 273 | 2005 |
Expansion of undifferentiated murine embryonic stem cells as aggregates in suspension culture bioreactors JT Cormier, NIZ Nieden, DE Rancourt, MS Kallos Tissue engineering 12 (11), 3233-3245, 2006 | 238 | 2006 |
Morphogenetic and regulatory mechanisms during developmental chondrogenesis: new paradigms for cartilage tissue engineering L Quintana, NI Zur Nieden, CE Semino Tissue Engineering Part B: Reviews 15 (1), 29-41, 2009 | 203 | 2009 |
Embryonic stem cells remain highly pluripotent following long term expansion as aggregates in suspension bioreactors NI zur Nieden, JT Cormier, DE Rancourt, MS Kallos Journal of biotechnology 129 (3), 421-432, 2007 | 179 | 2007 |
Molecular multiple endpoint embryonic stem cell test—a possible approach to test for the teratogenic potential of compounds NI Zur Nieden, G Kempka, HJ Ahr Toxicology and applied pharmacology 194 (3), 257-269, 2004 | 160 | 2004 |
Mesodermal fate decisions of a stem cell: the Wnt switch LA Davis, NI Zur Nieden Cellular and Molecular Life Sciences 65, 2658-2674, 2008 | 150 | 2008 |
Molecular markers in embryonic stem cells NI Zur Nieden, LJ Ruf, G Kempka, H Hildebrand, HJ Ahr Toxicology in vitro 15 (4-5), 455-461, 2001 | 101 | 2001 |
Hyperglycemia impairs skeletogenesis from embryonic stem cells by affecting osteoblast and osteoclast differentiation A Dienelt, NI zur Nieden Stem cells and development 20 (3), 465-474, 2011 | 90 | 2011 |
Reduced differentiation efficiency of murine embryonic stem cells in stirred suspension bioreactors JT Taiani, RJ Krawetz, NI Zur Nieden, YE Wu, MS Kallos, JR Matyas, ... Stem Cells and Development 19 (7), 989-998, 2010 | 79 | 2010 |
Glucose-induced oxidative stress reduces proliferation in embryonic stem cells via FOXO3A/β-catenin-dependent transcription of p21cip1 DLMC Descalzo, TS Satoorian, LM Walker, NRL Sparks, PY Pulyanina, ... Stem Cell Reports 7 (1), 55-68, 2016 | 67 | 2016 |
Gene profiling on mixed embryonic stem cell populations reveals a biphasic role for β-catenin in osteogenic differentiation NI zur Nieden, FD Price, LA Davis, RE Everitt, DE Rancourt Molecular Endocrinology 21 (3), 674-685, 2007 | 64 | 2007 |
Attenuated reovirus displays oncolysis with reduced host toxicity M Kim, KA Garant, NI Zur Nieden, T Alain, SD Loken, SJ Urbanski, ... British journal of cancer 104 (2), 290-299, 2011 | 58 | 2011 |
Comparing three novel endpoints for developmental osteotoxicity in the embryonic stem cell test NI zur Nieden, LA Davis, DE Rancourt Toxicology and applied pharmacology 247 (2), 91-97, 2010 | 46 | 2010 |
microRNA regulation of skeletal development SR Sera, NI Zur Nieden Current osteoporosis reports 15, 353-366, 2017 | 45 | 2017 |
NO–β-catenin crosstalk modulates primitive streak formation prior to embryonic stem cell osteogenic differentiation H Ding, KC Keller, IKC Martinez, RM Geransar, KO zur Nieden, ... Journal of Cell Science 125 (22), 5564-5577, 2012 | 43 | 2012 |
Wnt5a supports osteogenic lineage decisions in embryonic stem cells KC Keller, H Ding, R Tieu, NRL Sparks, DD Ehnes, NI Zur Nieden Stem cells and development 25 (13), 1020-1032, 2016 | 35 | 2016 |
Carboxyl-modified single-wall carbon nanotubes improve bone tissue formation in vitro and repair in an in vivo rat model A Barrientos-Durán, EM Carpenter, NI Zur Nieden, TI Malinin, ... International journal of nanomedicine, 4277-4291, 2014 | 33 | 2014 |
Embryonic stem cell test: stem cell use in predicting developmental cardiotoxicity and osteotoxicity B Kuske, PY Pulyanina, NI Nieden Developmental Toxicology: Methods and Protocols, 147-179, 2012 | 33 | 2012 |
Monolayer cultivation of osteoprogenitors shortens duration of the embryonic stem cell test while reliably predicting developmental osteotoxicity NI zur Nieden, LA Davis, DE Rancourt Toxicology 277 (1-3), 66-73, 2010 | 30 | 2010 |