Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro L Chen, C Gui, X Luo, Q Yang, S Günther, E Scandella, C Drosten, ... Journal of virology 79 (11), 7095-7103, 2005 | 238 | 2005 |
The nucleocapsid protein of SARS coronavirus has a high binding affinity to the human cellular heterogeneous nuclear ribonucleoprotein A1 H Luo, Q Chen, J Chen, K Chen, X Shen, H Jiang FEBS letters 579 (12), 2623-2628, 2005 | 144 | 2005 |
Nucleocapsid protein of SARS coronavirus tightly binds to human cyclophilin A C Luo, H Luo, S Zheng, C Gui, L Yue, C Yu, T Sun, P He, J Chen, J Shen, ... Biochemical and biophysical research communications 321 (3), 557-565, 2004 | 141 | 2004 |
A 3D model of SARS_CoV 3CL proteinase and its inhibitors design by virtual screening B Xiong, CS Gui, XY Xu, C Luo, J Chen, HB Luo, LL Chen, GW Li, T Sun, ... Acta Pharmacologica Sinica 24 (6), 497-504, 2003 | 113 | 2003 |
R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II H Zhu, M Huang, F Yang, Y Chen, ZH Miao, XH Qian, YF Xu, YX Qin, ... Molecular cancer therapeutics 6 (2), 484-495, 2007 | 90 | 2007 |
Carboxyl terminus of severe acute respiratory syndrome coronavirus nucleocapsid protein: self-association analysis and nucleic acid binding characterization H Luo, J Chen, K Chen, X Shen, H Jiang Biochemistry 45 (39), 11827-11835, 2006 | 87 | 2006 |
Ligand‐binding regulation of LXR/RXR and LXR/PPAR heterodimerizations: SPR technology‐based kinetic analysis correlated with molecular dynamics simulation L Yue, F Ye, C Gui, H Luo, J Cai, J Shen, K Chen, X Shen, H Jiang Protein science 14 (3), 812-822, 2005 | 76 | 2005 |
Severe acute respiratory syndrome coronavirus membrane protein interacts with nucleocapsid protein mostly through their carboxyl termini by electrostatic attraction H Luo, D Wu, C Shen, K Chen, X Shen, H Jiang The international journal of biochemistry & cell biology 38 (4), 589-599, 2006 | 67 | 2006 |
SR-rich motif plays a pivotal role in recombinant SARS coronavirus nucleocapsid protein multimerization H Luo, F Ye, K Chen, X Shen, H Jiang Biochemistry 44 (46), 15351-15358, 2005 | 66 | 2005 |
In vitro biochemical and thermodynamic characterization of nucleocapsid protein of SARS H Luo, F Ye, T Sun, L Yue, S Peng, J Chen, G Li, Y Du, Y Xie, Y Yang, ... Biophysical chemistry 112 (1), 15-25, 2004 | 64 | 2004 |
A Quadrupole Dalton-based multi-attribute method for product characterization, process development, and quality control of therapeutic proteins W Xu, RB Jimenez, R Mowery, H Luo, M Cao, N Agarwal, I Ramos, ... MAbs 9 (7), 1186-1196, 2017 | 61 | 2017 |
The dipeptide H‐Trp‐Glu‐OH shows highly antagonistic activity against PPARγ: bioassay with molecular modeling simulation F Ye, ZS Zhang, HB Luo, JH Shen, KX Chen, X Shen, HL Jiang Chembiochem 7 (1), 74-82, 2006 | 60 | 2006 |
Small envelope protein E of SARS: cloning, expression, purification, CD determination, and bioinformatics analysis X Shen, JH Xue, CY Yu, HB Luo, L Qin, XJ Yu, J Chen, LL Chen, B Xiong, ... Acta Pharmacologica Sinica 24 (6), 505-511, 2003 | 59 | 2003 |
Effects of salt-induced reversible self-association on the elution behavior of a monoclonal antibody in cation exchange chromatography H Luo, N Macapagal, K Newell, A Man, A Parupudi, Y Li, Y Li Journal of Chromatography A 1362, 186-193, 2014 | 57 | 2014 |
Enzymatic activity characterization of SARS coronavirus 3C‐like protease by fluorescence resonance energy transfer technique1 S Chen, L CHEN, H LUO, T Sun, J Chen, F Ye, J CAI, J SHEN, X Shen, ... Acta Pharmacologica Sinica 26 (1), 99-106, 2005 | 50 | 2005 |
Molecular cloning, expression, purification, and mass spectrometric characterization of 3C-like protease of SARS coronavirus H Sun, H Luo, C Yu, T Sun, J Chen, S Peng, J Qin, J Shen, Y Yang, Y Xie, ... Protein expression and purification 32 (2), 302-308, 2003 | 36 | 2003 |
Double-peak elution profile of a monoclonal antibody in cation exchange chromatography is caused by histidine-protonation-based charge variants H Luo, M Cao, K Newell, C Afdahl, J Wang, WK Wang, Y Li Journal of Chromatography A 1424, 92-101, 2015 | 33 | 2015 |
Cathepsin L causes proteolytic cleavage of Chinese‐Hamster‐Ovary cell expressed proteins during processing and storage: Identification, characterization, and mitigation H Luo, L Tie, M Cao, AK Hunter, TM Pabst, J Du, R Field, Y Li, WK Wang Biotechnology Progress 35 (1), e2732, 2019 | 30 | 2019 |
An automated and qualified platform method for site-specific succinimide and deamidation quantitation using low-pH peptide mapping M Cao, W Xu, B Niu, I Kabundi, H Luo, M Prophet, W Chen, D Liu, ... Journal of Pharmaceutical Sciences 108 (11), 3540-3549, 2019 | 29 | 2019 |
MFTZ-1, an actinomycetes subspecies–derived antitumor macrolide, functions as a novel topoisomerase II poison CY Xie, H Zhu, LP Lin, ZH Miao, MY Geng, YJ Cai, Y Chen, HJ Zhao, ... Molecular Cancer Therapeutics 6 (11), 3059-3070, 2007 | 28 | 2007 |