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Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeutics
AC Mita, MM Mita, ST Nawrocki, FJ Giles
Clinical cancer research 14 (16), 5000-5005, 2008
10682008
Phase II study of sorafenib in patients with metastatic or recurrent sarcomas
RG Maki, DR D'Adamo, ML Keohan, M Saulle, SM Schuetze, SD Undevia, ...
Journal of Clinical Oncology 27 (19), 3133-3140, 2009
6602009
Single-arm phases 1 and 2 trial of niraparib in combination with pembrolizumab in patients with recurrent platinum-resistant ovarian carcinoma
PA Konstantinopoulos, S Waggoner, GA Vidal, M Mita, JW Moroney, ...
JAMA oncology 5 (8), 1141-1149, 2019
4332019
Activity of exemestane in metastatic breast cancer after failure of nonsteroidal aromatase inhibitors: a phase II trial
PE Lønning, E Bajetta, R Murray, M Tubiana-Hulin, PD Eisenberg, ...
Journal of Clinical Oncology 18 (11), 2234-2244, 2000
4172000
LXR/ApoE activation restricts innate immune suppression in cancer
MF Tavazoie, I Pollack, R Tanqueco, BN Ostendorf, BS Reis, ...
Cell 172 (4), 825-840. e18, 2018
3922018
Phase I pharmacokinetic and biologic correlative study of mapatumumab, a fully human monoclonal antibody with agonist activity to tumor necrosis factor–related apoptosis …
AW Tolcher, M Mita, NJ Meropol, M von Mehren, A Patnaik, K Padavic, ...
Journal of Clinical Oncology 25 (11), 1390-1396, 2007
3752007
Histone deacetylase inhibitor panobinostat induces clinical responses with associated alterations in gene expression profiles in cutaneous T-cell lymphoma
L Ellis, Y Pan, GK Smyth, DJ George, C McCormack, R Williams-Truax, ...
Clinical Cancer Research 14 (14), 4500-4510, 2008
3452008
Open-label clinical trial of niraparib combined with pembrolizumab for treatment of advanced or metastatic triple-negative breast cancer
S Vinayak, SM Tolaney, L Schwartzberg, M Mita, G McCann, AR Tan, ...
JAMA oncology 5 (8), 1132-1140, 2019
3392019
Phase I trial of the novel mammalian target of rapamycin inhibitor deforolimus (AP23573; MK-8669) administered intravenously daily for 5 days every 2 weeks to patients with …
MM Mita, AC Mita, QS Chu, EK Rowinsky, GJ Fetterly, M Goldston, ...
Journal of Clinical Oncology 26 (3), 361-367, 2008
3152008
Combined autophagy and HDAC inhibition: a phase I safety, tolerability, pharmacokinetic, and pharmacodynamic analysis of hydroxychloroquine in combination with the HDAC …
D Mahalingam, M Mita, J Sarantopoulos, L Wood, RK Amaravadi, ...
Autophagy 10 (8), 1403-1414, 2014
3062014
Phase II study of the mammalian target of rapamycin inhibitor ridaforolimus in patients with advanced bone and soft tissue sarcomas
SP Chawla, AP Staddon, LH Baker, SM Schuetze, AW Tolcher, ...
Journal of Clinical Oncology 30 (1), 78-84, 2012
2912012
Phase I study of PSMA-targeted docetaxel-containing nanoparticle BIND-014 in patients with advanced solid tumors
DD Von Hoff, MM Mita, RK Ramanathan, GJ Weiss, AC Mita, PM LoRusso, ...
Clinical Cancer Research 22 (13), 3157-3163, 2016
2632016
The molecular target of rapamycin (mTOR) as a therapeutic target against cancer
MM Mita, A Mita, EK Rowinsky
Cancer biology & therapy 2 (sup1), 168-176, 2003
2472003
Autophagy inhibition enhances vorinostat‐induced apoptosis via ubiquitinated protein accumulation
JS Carew, EC Medina, JA Esquivel II, D Mahalingam, R Swords, K Kelly, ...
Journal of cellular and molecular medicine 14 (10), 2448-2459, 2010
2382010
Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer
CE Geyer Jr, JE Garber, RD Gelber, G Yothers, M Taboada, L Ross, ...
Annals of oncology 33 (12), 1250-1268, 2022
1992022
Mammalian target of rapamycin: a new molecular target for breast cancer
MM Mita, A Mita, EK Rowinsky
Clinical breast cancer 4 (2), 126-137, 2003
1872003
Randomized phase II trial of the cyclin-dependent kinase inhibitor dinaciclib (MK-7965) versus capecitabine in patients with advanced breast cancer
MM Mita, AA Joy, A Mita, K Sankhala, YM Jou, D Zhang, P Statkevich, ...
Clinical breast cancer 14 (3), 169-176, 2014
1832014
Phase I and pharmacokinetic study of lexatumumab (HGS-ETR2) given every 2 weeks in patients with advanced solid tumors
HA Wakelee, A Patnaik, BI Sikic, M Mita, NL Fox, R Miceli, SJ Ullrich, ...
Annals of Oncology 21 (2), 376-381, 2010
1792010
First-in-human phase I dose-escalation study of the HSP90 inhibitor AUY922 in patients with advanced solid tumors
C Sessa, GI Shapiro, KN Bhalla, C Britten, KS Jacks, M Mita, ...
Clinical Cancer Research 19 (13), 3671-3680, 2013
1712013
A phase I study of eribulin mesylate (E7389), a mechanistically novel inhibitor of microtubule dynamics, in patients with advanced solid malignancies
S Goel, AC Mita, M Mita, EK Rowinsky, QS Chu, N Wong, C Desjardins, ...
Clinical Cancer Research 15 (12), 4207-4212, 2009
1692009
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