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An orally bioavailable chemical probe of the lysine methyltransferases EZH2 and EZH1 KD Konze, A Ma, F Li, D Barsyte-Lovejoy, T Parton, CJ MacNevin, F Liu, ... ACS chemical biology 8 (6), 1324-1334, 2013 | 484 | 2013 |
Preferential occupancy of histone variant H2AZ at inactive promoters influences local histone modifications and chromatin remodeling B Li, SG Pattenden, D Lee, J Gutiérrez, J Chen, C Seidel, J Gerton, ... Proceedings of the National Academy of Sciences 102 (51), 18385-18390, 2005 | 394 | 2005 |
Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia B Xu, DM On, A Ma, T Parton, KD Konze, SG Pattenden, DF Allison, L Cai, ... Blood, The Journal of the American Society of Hematology 125 (2), 346-357, 2015 | 235 | 2015 |
Infrequently transcribed long genes depend on the Set2/Rpd3S pathway for accurate transcription B Li, M Gogol, M Carey, SG Pattenden, C Seidel, JL Workman Genes & development 21 (11), 1422-1430, 2007 | 232 | 2007 |
The proteasome regulatory particle alters the SAGA coactivator to enhance its interactions with transcriptional activators D Lee, E Ezhkova, B Li, SG Pattenden, WP Tansey, JL Workman Cell 123 (3), 423-436, 2005 | 227 | 2005 |
Rtr1 is a CTD phosphatase that regulates RNA polymerase II during the transition from serine 5 to serine 2 phosphorylation AL Mosley, SG Pattenden, M Carey, S Venkatesh, JM Gilmore, L Florens, ... Molecular cell 34 (2), 168-178, 2009 | 211 | 2009 |
A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1 JI Stuckey, BM Dickson, N Cheng, Y Liu, JL Norris, SH Cholensky, ... Nature chemical biology 12 (3), 180-187, 2016 | 165 | 2016 |
Interferon-γ-induced chromatin remodeling at the CIITA locus is BRG1 dependent SG Pattenden, R Klose, E Karaskov, R Bremner The EMBO journal 21 (8), 1978-1986, 2002 | 137 | 2002 |
Diverse functions of WD40 repeat proteins in histone recognition T Suganuma, SG Pattenden, JL Workman Genes & development 22 (10), 1265-1268, 2008 | 113 | 2008 |
Apical role for BRG1 in cytokine-induced promoter assembly Z Ni, E Karaskov, T Yu, SM Callaghan, S Der, DS Park, Z Xu, ... Proceedings of the National Academy of Sciences 102 (41), 14611-14616, 2005 | 106 | 2005 |
Highly reproducible label free quantitative proteomic analysis of RNA polymerase complexes AL Mosley, ME Sardiu, SG Pattenden, JL Workman, L Florens, ... Molecular & Cellular Proteomics 10 (2), S1-S13, 2011 | 90 | 2011 |
Tumor endothelial cells with distinct patterns of TGFβ-driven endothelial-to-mesenchymal transition L Xiao, DJ Kim, CL Davis, JV McCann, JM Dunleavey, AK Vanderlinden, ... Cancer research 75 (7), 1244-1254, 2015 | 73 | 2015 |
Histone H4 lysine 16 acetylation breaks the genome's silence WJ Shia, SG Pattenden, JL Workman Genome biology 7, 1-3, 2006 | 62 | 2006 |
Cavitation enhancing nanodroplets mediate efficient DNA fragmentation in a bench top ultrasonic water bath SK Kasoji, SG Pattenden, EP Malc, CN Jayakody, JK Tsuruta, ... PLoS One 10 (7), e0133014, 2015 | 45 | 2015 |
Chromatin remodeling controls Kaposi's sarcoma-associated herpesvirus reactivation from latency SE Hopcraft, SG Pattenden, LI James, S Frye, DP Dittmer, B Damania PLoS pathogens 14 (9), e1007267, 2018 | 39 | 2018 |
A role for widely interspaced zinc finger (WIZ) in retention of the G9a methyltransferase on chromatin JM Simon, JS Parker, F Liu, SB Rothbart, S Ait-Si-Ali, BD Strahl, J Jin, ... Journal of Biological Chemistry 290 (43), 26088-26102, 2015 | 36 | 2015 |
A chemical tool for in vitro and in vivo precipitation of lysine methyltransferase G9a KD Konze, SG Pattenden, F Liu, D Barsyte‐Lovejoy, F Li, JM Simon, ... ChemMedChem 9 (3), 549-553, 2014 | 34 | 2014 |
pRB is required for interferon-γ-induction of the MHC class II Aβ gene X Zhu, S Pattenden, R Bremner Oncogene 18 (35), 4940-4947, 1999 | 34 | 1999 |
High-throughput small molecule screen identifies inhibitors of aberrant chromatin accessibility SG Pattenden, JM Simon, A Wali, CN Jayakody, J Troutman, ... Proceedings of the National Academy of Sciences 113 (11), 3018-3023, 2016 | 32 | 2016 |