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Don Siegel
Don Siegel
Professor of Pathology and Laboaratory Medicine, University of Pennsylvania
Verified email at pennmedicine.upenn.edu
Title
Cited by
Cited by
Year
Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
JA Fraietta, SF Lacey, EJ Orlando, I Pruteanu-Malinici, M Gohil, S Lundh, ...
Nature medicine 24 (5), 563-571, 2018
14302018
CRISPR-engineered T cells in patients with refractory cancer
EA Stadtmauer, JA Fraietta, MM Davis, AD Cohen, KL Weber, E Lancaster, ...
Science 367 (6481), eaba7365, 2020
12102020
NY-ESO-1–specific TCR–engineered T cells mediate sustained antigen-specific antitumor effects in myeloma
AP Rapoport, EA Stadtmauer, GK Binder-Scholl, O Goloubeva, DT Vogl, ...
Nature medicine 21 (8), 914-921, 2015
9942015
B cell maturation antigen–specific CAR T cells are clinically active in multiple myeloma
AD Cohen, AL Garfall, EA Stadtmauer, JJ Melenhorst, SF Lacey, ...
The Journal of clinical investigation 129 (6), 2210-2221, 2019
6712019
Decade-long leukaemia remissions with persistence of CD4+ CAR T cells
JJ Melenhorst, GM Chen, M Wang, DL Porter, C Chen, MKA Collins, ...
Nature 602 (7897), 503-509, 2022
5542022
PSMA-targeting TGFβ-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial
V Narayan, JS Barber-Rotenberg, IY Jung, SF Lacey, AJ Rech, MM Davis, ...
Nature medicine 28 (4), 724-734, 2022
2552022
Genetic and functional characterization of human pemphigus vulgaris monoclonal autoantibodies isolated by phage display
AS Payne, K Ishii, S Kacir, C Lin, H Li, Y Hanakawa, K Tsunoda, ...
The Journal of clinical investigation 115 (4), 888-899, 2005
2432005
Inappropriate testing for diarrheal diseases in the hospital
DL Siegel, PH Edelstein, I Nachamkin
Jama 263 (7), 979-982, 1990
2431990
Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma
AL Garfall, EA Stadtmauer, WT Hwang, SF Lacey, JJ Melenhorst, ...
JCI insight 3 (8), 2018
2022018
Impact of pre-existing immunity on gene transfer to nonhuman primate liver with adeno-associated virus 8 vectors
L Wang, R Calcedo, P Bell, J Lin, RL Grant, DL Siegel, JM Wilson
Human gene therapy 22 (11), 1389-1401, 2011
2022011
Genetic analysis of autoantibodies in idiopathic thrombocytopenic purpura reveals evidence of clonal expansion and somatic mutation
JH Roark, JB Bussel, DB Cines, DL Siegel
Blood, The Journal of the American Society of Hematology 100 (4), 1388-1398, 2002
1922002
Isolation of cell surface-specific human monoclonal antibodies using phage display and magnetically-activated cell sorting: applications in immunohematology
DL Siegel, TY Chang, SL Russell, VY Bunya
Journal of immunological methods 206 (1-2), 73-85, 1997
1641997
T-cell phenotypes associated with effective CAR T-cell therapy in postinduction vs relapsed multiple myeloma
AL Garfall, EK Dancy, AD Cohen, WT Hwang, JA Fraietta, MM Davis, ...
Blood advances 3 (19), 2812-2815, 2019
1602019
Bispecific and split CAR T cells targeting CD13 and TIM3 eradicate acute myeloid leukemia
X He, Z Feng, J Ma, S Ling, Y Cao, B Gurung, Y Wu, BW Katona, ...
Blood, The Journal of the American Society of Hematology 135 (10), 713-723, 2020
1592020
Recombinant monoclonal antibody technology
DL Siegel
Transfusion clinique et biologique 9 (1), 15-22, 2002
1552002
Partial purification and characterization of an actin-bundling protein, band 4.9, from human erythrocytes.
DL Siegel, D Branton
The Journal of cell biology 100 (3), 775-785, 1985
1511985
Characterization of a murine monoclonal antibody that mimics heparin-induced thrombocytopenia antibodies
GM Arepally, S Kamei, KS Park, K Kamei, ZQ Li, W Liu, DL Siegel, ...
Blood, The Journal of the American Society of Hematology 95 (5), 1533-1540, 2000
1492000
Phage antibody display libraries: a powerful antibody discovery platform for immunotherapy
A Zhao, MR Tohidkia, DL Siegel, G Coukos, Y Omidi
Critical reviews in biotechnology 36 (2), 276-289, 2016
1252016
Humanized CD19-targeted chimeric antigen receptor (CAR) T cells in CAR-naive and CAR-exposed children and young adults with relapsed or refractory acute lymphoblastic leukemia
RM Myers, Y Li, A Barz Leahy, DM Barrett, DT Teachey, C Callahan, ...
Journal of Clinical Oncology 39 (27), 3044-3055, 2021
1202021
Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study
JH Beigel, P Tebas, MC Elie-Turenne, E Bajwa, TE Bell, CB Cairns, ...
The Lancet Respiratory Medicine 5 (6), 500-511, 2017
1202017
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