Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models MJD Daniels, J Rivers-Auty, T Schilling, NG Spencer, W Watremez, ... Nature communications 7 (1), 12504, 2016 | 426 | 2016 |
Inflammasome-dependent IL-1β release depends upon membrane permeabilisation F Martín-Sánchez, C Diamond, M Zeitler, AI Gomez, A Baroja-Mazo, ... Cell Death & Differentiation 23 (7), 1219-1231, 2016 | 287 | 2016 |
Boron-based inhibitors of the NLRP3 inflammasome AG Baldwin, J Rivers-Auty, MJD Daniels, CS White, CH Schwalbe, ... Cell Chemical Biology 24 (11), 1321-1335. e5, 2017 | 104 | 2017 |
Redefining the ancestral origins of the interleukin-1 superfamily J Rivers-Auty, MJD Daniels, I Colliver, DL Robertson, D Brough Nature communications 9 (1), 1156, 2018 | 93 | 2018 |
The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes VS Tapia, MJD Daniels, P Palazón-Riquelme, M Dewhurst, NM Luheshi, ... Journal of Biological Chemistry 294 (21), 8325-8335, 2019 | 84 | 2019 |
Unconventional pathways of secretion contribute to inflammation MJD Daniels, D Brough International journal of molecular sciences 18 (1), 102, 2017 | 61 | 2017 |
Zinc status alters Alzheimer's disease progression through NLRP3-dependent inflammation J Rivers-Auty, VS Tapia, CS White, MJD Daniels, S Drinkall, PT Kennedy, ... Journal of Neuroscience 41 (13), 3025-3038, 2021 | 56 | 2021 |
P2X7 receptor‐dependent tuning of gut epithelial responses to infection SW Huang, C Walker, J Pennock, K Else, W Muller, MJD Daniels, ... Immunology and cell biology 95 (2), 178-188, 2017 | 43 | 2017 |
Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer’s disease via MFG-E8 M Tzioras, MJD Daniels, C Davies, P Baxter, D King, S McKay, B Varga, ... Cell Reports Medicine 4 (9), 2023 | 26 | 2023 |
Altered synaptic ingestion by human microglia in Alzheimer’s disease M Tzioras, MJD Daniels, D King, K Popovic, RK Holloway, AJ Stevenson, ... BioRxiv 10, 795930, 2019 | 20 | 2019 |
Random forest modelling demonstrates microglial and protein misfolding features to be key phenotypic markers in C9orf72‐ALS OM Rifai, J Longden, J O'Shaughnessy, MDE Sewell, J Pate, K McDade, ... The Journal of pathology 258 (4), 366-381, 2022 | 12 | 2022 |
Treatment with IgM‐enriched intravenous immunoglobulins enhances clearance of stroke‐associated bacterial lung infection L McCulloch, AJ Harris, A Malbon, MJD Daniels, M Younas, JR Grainger, ... Immunology 167 (4), 558-575, 2022 | 8 | 2022 |
Deep proteomic analysis of human microglia and model systems reveal fundamental biological differences of in vitro and ex vivo cells AF Lloyd, A Martinez-Muriana, P Hou, E Davis, R Mancuso, AJ Brenes, ... BioRxiv, 1-30, 2022 | 8 | 2022 |
Cystatin F (Cst7) drives sex-dependent changes in microglia in an amyloid-driven model of Alzheimer’s disease MJD Daniels, L Lefevre, S Szymkowiak, A Drake, L McCulloch, M Tzioras, ... Elife 12, e85279, 2023 | 6 | 2023 |
CRISPR/Cas9 mediated mutation of mouse IL-1α nuclear localisation sequence abolishes expression MJD Daniels, AD Adamson, N Humphreys, D Brough Scientific Reports 7 (1), 17077, 2017 | 3 | 2017 |
Protease-activated receptor 2 activation induces behavioural changes associated with depression-like behaviour through microglial-independent modulation of inflammatory cytokines S Moudio, A Willis, K Pytka, R Abulkassim, RR Brett, JF Webster, C Wozny, ... Psychopharmacology 239 (1), 229-242, 2022 | 2 | 2022 |
A role for astrocytes and microglia in synapse loss in Alzheimer’s disease M Tzioras, M Daniels, C Davies, M Hooley, X He, OR Dando, ... Alzheimer's & Dementia 17, e052532, 2021 | 1 | 2021 |
TREM2-regulated microglial reactivity confers resilience against vascular contributions to white matter injury and cognitive decline S Szymkowiak, M Redzic, A Patir, C Latta, M Daniels, J Barrington, ... Cerebral Circulation-Cognition and Behavior 6, 100318, 2024 | | 2024 |
Creating connections: developing an online space for cross-regional mentorship and network building in the dementia research field J Fullerton, C Bettencourt, M Daniels, F Mclean, S Simpson, A Smith, ... AMRC open research 4, 2022 | | 2022 |
Deep proteomic analysis of microglia reveals fundamental biological differences between model systems AF Lloyd, A Martinez-Muriana, E Davis, MJD Daniels, P Hou, R Mancuso, ... bioRxiv, 2022.07. 07.498804, 2022 | | 2022 |