The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease S Youssef, O Stüve, JC Patarroyo, PJ Ruiz, JL Radosevich, EM Hur, ... Nature 420 (6911), 78-84, 2002 | 1371 | 2002 |
1,25-Dihydroxyvitamin D3 Ameliorates Th17 Autoimmunity via Transcriptional Modulation of Interleukin-17A S Joshi, LC Pantalena, XK Liu, SL Gaffen, H Liu, C Rohowsky-Kochan, ... Molecular and cellular biology 31 (17), 3653-3669, 2011 | 597 | 2011 |
Thymic selection determines γδ T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon γ KDC Jensen, X Su, S Shin, L Li, S Youssef, S Yamasaki, L Steinman, ... Immunity 29 (1), 90-100, 2008 | 538 | 2008 |
Type II monocytes modulate T cell–mediated central nervous system autoimmune disease MS Weber, T Prod'homme, S Youssef, SE Dunn, CD Rundle, L Lee, ... Nature medicine 13 (8), 935-943, 2007 | 534 | 2007 |
Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite M Platten, PP Ho, S Youssef, P Fontoura, H Garren, EM Hur, R Gupta, ... Science 310 (5749), 850-855, 2005 | 526 | 2005 |
Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine MV Karpuj, MW Becher, JE Springer, D Chabas, S Youssef, R Pedotti, ... Nature medicine 8 (2), 143-149, 2002 | 461 | 2002 |
Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells EM Hur, S Youssef, ME Haws, SY Zhang, RA Sobel, L Steinman Nature immunology 8 (1), 74-83, 2007 | 386 | 2007 |
Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1-and TH17-mediated autoimmunity M Platten, S Youssef, EM Hur, PP Ho, MH Han, TV Lanz, LK Phillips, ... Proceedings of the National Academy of Sciences 106 (35), 14948-14953, 2009 | 356 | 2009 |
Extensive fusion of haematopoietic cells with Purkinje neurons in response to chronic inflammation CB Johansson, S Youssef, K Koleckar, C Holbrook, R Doyonnas, ... Nature cell biology 10 (5), 575-583, 2008 | 275 | 2008 |
Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study KM Hastie, H Li, D Bedinger, SL Schendel, SM Dennison, K Li, ... Science 374 (6566), 472-478, 2021 | 271 | 2021 |
Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin SE Dunn, S Youssef, MJ Goldstein, T Prod'homme, MS Weber, SS Zamvil, ... The Journal of experimental medicine 203 (2), 401-412, 2006 | 264 | 2006 |
Peroxisome proliferator–activated receptor (PPAR) α expression in T cells mediates gender differences in development of T cell–mediated autoimmunity SE Dunn, SS Ousman, RA Sobel, L Zuniga, SE Baranzini, S Youssef, ... The Journal of experimental medicine 204 (2), 321-330, 2007 | 216 | 2007 |
Statins as potential therapeutic agents in neuroinflammatory disorders O Stüve, S Youssef, L Steinman, SS Zamvil Current opinion in neurology 16 (3), 393-401, 2003 | 208 | 2003 |
Neutralizing antibodies to IFN-γ-inducing factor prevent experimental autoimmune encephalomyelitis G Wildbaum, S Youssef, N Grabie, N Karin The Journal of Immunology 161 (11), 6368-6374, 1998 | 181 | 1998 |
Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination R Pedotti, JJ DeVoss, S Youssef, D Mitchell, J Wedemeyer, R Madanat, ... Proceedings of the National Academy of Sciences 100 (4), 1867-1872, 2003 | 163 | 2003 |
Differential regulation of chemokines by IL-17 in colonic epithelial cells JW Lee, P Wang, MG Kattah, S Youssef, L Steinman, K DeFea, DS Straus The Journal of Immunology 181 (9), 6536-6545, 2008 | 157 | 2008 |
Long-lasting protective immunity to experimental autoimmune encephalomyelitis following vaccination with naked DNA encoding CC chemokines S Youssef, G Wildbaum, G Maor, N Lanir, A Gour-Lavie, N Grabie, N Karin The Journal of Immunology 161 (8), 3870-3879, 1998 | 157 | 1998 |
CC chemokine–encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis S Youssef, G Maor, G Wildbaum, N Grabie, A Gour-Lavie, N Karin The Journal of clinical investigation 106 (3), 361-371, 2000 | 137 | 2000 |
Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity O Stüve, S Youssef, MS Weber, S Nessler, HC von Büdingen, B Hemmer, ... The Journal of clinical investigation 116 (4), 1037-1044, 2006 | 132 | 2006 |
The role of the MHC class II transactivator in class II expression and antigen presentation by astrocytes and in susceptibility to central nervous system autoimmune disease O Stuve, S Youssef, AJ Slavin, CL King, JC Patarroyo, DL Hirschberg, ... The Journal of Immunology 169 (12), 6720-6732, 2002 | 118 | 2002 |