| ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression DR McCulloch, CM Nelson, LJ Dixon, DL Silver, JD Wylie, V Lindner, ... Developmental cell 17 (5), 687-698, 2009 | 269 | 2009 |
| Characterization of proADAMTS5 processing by proprotein convertases JM Longpré, DR McCulloch, BH Koo, JP Alexander, SS Apte, R Leduc The international journal of biochemistry & cell biology 41 (5), 1116-1126, 2009 | 137 | 2009 |
| Expression of the disintegrin metalloprotease, ADAM-10, in prostate cancer and its regulation by dihydrotestosterone, insulin-like growth factor I, and epidermal growth factor … DR McCulloch, P Akl, H Samaratunga, AC Herington, DM Odorico Clinical cancer research 10 (1), 314-323, 2004 | 134 | 2004 |
| Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease LE Dupuis, DR McCulloch, JD McGarity, A Bahan, A Wessels, D Weber, ... Developmental biology 357 (1), 152-164, 2011 | 133 | 2011 |
| The expression of the ADAMs proteases in prostate cancer cell lines and their regulation by dihydrotestosterone DR McCulloch, M Harvey, AC Herington Molecular and Cellular Endocrinology 167 (1-2), 11-21, 2000 | 104 | 2000 |
| Adamts5, the gene encoding a proteoglycan-degrading metalloprotease, is expressed by specific cell lineages during mouse embryonic development and in adult tissues DR McCulloch, C Le Goff, S Bhatt, LJ Dixon, JD Sandy, SS Apte Gene Expression Patterns 9 (5), 314-323, 2009 | 101 | 2009 |
| Current and emerging therapeutic strategies for preventing inflammation and aggrecanase-mediated cartilage destruction in arthritis CM Dancevic, DR McCulloch Arthritis research & therapy 16, 1-11, 2014 | 89 | 2014 |
| Versican processing by a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats proteinases-5 and-15 facilitates myoblast fusion N Stupka, C Kintakas, JD White, FW Fraser, M Hanciu, N Aramaki-Hattori, ... Journal of Biological Chemistry 288 (3), 1907-1917, 2013 | 82 | 2013 |
| The extracellular matrix in cancer progression: Role of hyalectan proteoglycans and ADAMTS enzymes MJ Binder, S McCoombe, ED Williams, DR McCulloch, AC Ward Cancer letters 385, 55-64, 2017 | 74 | 2017 |
| Modeling of enzyme–substrate complexes for the metalloproteases MMP-3, ADAM-9 and ADAM-10 S Manzetti, DR McCulloch, AC Herington, D van der Spoel Journal of computer-aided molecular design 17, 551-565, 2003 | 68 | 2003 |
| Upregulated MT1-MMP/TIMP-2 axis in the TSU-Pr1-B1/B2 model of metastatic progression in transitional cell carcinoma of the bladder CL Chaffer, B Dopheide, DR McCulloch, AB Lee, JM Moseley, ... Clinical & experimental metastasis 22, 115-125, 2005 | 63 | 2005 |
| Biosynthesis and expression of a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats-15: a novel versican-cleaving proteoglycanase CM Dancevic, FW Fraser, AD Smith, N Stupka, AC Ward, DR McCulloch Journal of Biological Chemistry 288 (52), 37267-37276, 2013 | 60 | 2013 |
| Granulocyte colony-stimulating factor receptor signalling via Janus kinase 2/signal transducer and activator of transcription 3 in ovarian cancer J Kumar, FW Fraser, C Riley, N Ahmed, DR McCulloch, AC Ward British journal of cancer 110 (1), 133-145, 2014 | 58* | 2014 |
| BM18: A novel androgen‐dependent human prostate cancer xenograft model derived from a bone metastasis DR McCulloch, K Opeskin, EW Thompson, ED Williams The Prostate 65 (1), 35-43, 2005 | 53 | 2005 |
| ADAMTS5 is a critical regulator of virus-specific T cell immunity M McMahon, S Ye, L Izzard, D Dlugolenski, RA Tripp, AGD Bean, ... PLoS Biology 14 (11), e1002580, 2016 | 51 | 2016 |
| Leptin receptor signaling via Janus kinase 2/Signal transducer and activator of transcription 3 impacts on ovarian cancer cell phenotypes J Kumar, H Fang, DR McCulloch, T Crowley, AC Ward Oncotarget 8 (55), 93530, 2017 | 45 | 2017 |
| The evolutionary conservation of the A Disintegrin-like and Metalloproteinase domain with Thrombospondin-1 motif metzincins across vertebrate species and their expression in … FG Brunet, FW Fraser, MJ Binder, AD Smith, C Kintakas, CM Dancevic, ... BMC Evolutionary Biology 15, 1-15, 2015 | 44 | 2015 |
| ADAMTS4 and ADAMTS5 knockout mice are protected from versican but not aggrecan or brevican proteolysis during spinal cord injury K Demircan, V Topcu, T Takigawa, S Akyol, T Yonezawa, G Ozturk, ... BioMed Research International 2014 (1), 693746, 2014 | 43 | 2014 |
| The metalloproteinase-proteoglycans ADAMTS7 and ADAMTS12 provide an innate, tendon-specific protective mechanism against heterotopic ossification TJ Mead, DR McCulloch, JC Ho, Y Du, SM Adams, DE Birk, SS Apte JCI insight 3 (7), 2018 | 42 | 2018 |
| Emerging roles for ADAMTS5 during development and disease C Kintakas, DR McCulloch Matrix Biology 30 (5-6), 311-317, 2011 | 39 | 2011 |
Suneel ApteCleveland ClinicVerified email at ccf.org
