Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway H Ashrafian, G Czibik, M Bellahcene, D Aksentijević, AC Smith, ... Cell metabolism 15 (3), 361-371, 2012 | 303 | 2012 |
Two‐dimensional J‐resolved NMR spectroscopy: review of a key methodology in the metabolomics toolbox C Ludwig, MR Viant Phytochemical Analysis: An International Journal of Plant Chemical and …, 2010 | 289 | 2010 |
Metabonomics of human fecal extracts characterize ulcerative colitis, Crohn’s disease and healthy individuals JT Bjerrum, Y Wang, F Hao, M Coskun, C Ludwig, U Günther, OH Nielsen Metabolomics 11, 122-133, 2015 | 252 | 2015 |
Improved classification accuracy in 1-and 2-dimensional NMR metabolomics data using the variance stabilising generalised logarithm transformation HM Parsons, C Ludwig, UL Günther, MR Viant BMC bioinformatics 8, 1-16, 2007 | 251 | 2007 |
Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism C Lussey-Lepoutre, KER Hollinshead, C Ludwig, M Menara, A Morin, ... Nature communications 6 (1), 8784, 2015 | 230 | 2015 |
Optimized metabolite extraction from blood serum for 1H nuclear magnetic resonance spectroscopy S Tiziani, AH Emwas, A Lodi, C Ludwig, CM Bunce, MR Viant, UL Günther Analytical biochemistry 377 (1), 16-23, 2008 | 229 | 2008 |
Birmingham Metabolite Library: a publicly accessible database of 1-D 1H and 2-D 1H J-resolved NMR spectra of authentic metabolite standards (BML-NMR) C Ludwig, JM Easton, A Lodi, S Tiziani, SE Manzoor, AD Southam, ... Metabolomics 8, 8-18, 2012 | 165 | 2012 |
MetaboLab-advanced NMR data processing and analysis for metabolomics C Ludwig, UL Günther BMC bioinformatics 12, 1-6, 2011 | 163 | 2011 |
COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access RM Salek, S Neumann, D Schober, J Hummel, K Billiau, J Kopka, ... Metabolomics 11, 1587-1597, 2015 | 160 | 2015 |
NMRLAB—advanced NMR data processing in Matlab UL Günther, C Ludwig, H Rüterjans Journal of Magnetic Resonance 145 (2), 201-208, 2000 | 125 | 2000 |
Fast targeted multidimensional NMR metabolomics of colorectal cancer C Ludwig, DG Ward, A Martin, MR Viant, T Ismail, PJ Johnson, ... Magnetic Resonance in Chemistry 47 (S1), S68-S73, 2009 | 106 | 2009 |
A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia J Adam, M Yang, C Bauerschmidt, M Kitagawa, L O’Flaherty, ... Cell reports 3 (5), 1440-1448, 2013 | 100 | 2013 |
Metabolic plasticity in CLL: adaptation to the hypoxic niche KM Koczula, C Ludwig, R Hayden, L Cronin, G Pratt, H Parry, D Tennant, ... Leukemia 30 (1), 65-73, 2016 | 94 | 2016 |
Oncogenic IDH1 mutations promote enhanced proline synthesis through PYCR1 to support the maintenance of mitochondrial redox homeostasis KER Hollinshead, H Munford, KL Eales, C Bardella, C Li, ... Cell reports 22 (12), 3107-3114, 2018 | 86 | 2018 |
Ligand based NMR methods for drug discovery C Ludwig, UL Guenther Front Biosci 14 (4565-74), 24, 2009 | 85 | 2009 |
SALMON: solvent accessibility, ligand binding, and mapping of ligand orientation by NMR spectroscopy C Ludwig, PJA Michiels, X Wu, KL Kavanagh, E Pilka, A Jansson, ... Journal of medicinal chemistry 51 (1), 1-3, 2008 | 82 | 2008 |
Global 30-day outcomes after bariatric surgery during the COVID-19 pandemic (GENEVA): an international cohort study R Singhal, AA Tahrani, C Ludwig, K Mahawar, A Abou-Mrad-Fricquegnon, ... The lancet Diabetes & endocrinology 9 (1), 7-9, 2021 | 73 | 2021 |
PhenoMeNal: processing and analysis of metabolomics data in the cloud K Peters, J Bradbury, S Bergmann, M Capuccini, M Cascante, P de Atauri, ... GigaScience 8 (2), giy149, 2019 | 73 | 2019 |
Metabolic changes in flatfish hepatic tumours revealed by NMR-based metabolomics and metabolic correlation networks AD Southam, JM Easton, GD Stentiford, C Ludwig, TN Arvanitis, MR Viant Journal of proteome research 7 (12), 5277-5285, 2008 | 72 | 2008 |
Solution structure and backbone dynamics of human epidermal-type fatty acid-binding protein (E-FABP) LH Gutiérrez-González, C Ludwig, C Hohoff, M Rademacher, T Hanhoff, ... Biochemical Journal 364 (3), 725-737, 2002 | 70 | 2002 |