Structural basis of α-scorpion toxin action on Nav channels T Clairfeuille, A Cloake, DT Infield, JP Llongueras, CP Arthur, ZR Li, ... Science 363 (6433), eaav8573, 2019 | 170 | 2019 |
Engineered transfer RNAs for suppression of premature termination codons JD Lueck, JS Yoon, A Perales-Puchalt, AL Mackey, DT Infield, MA Behlke, ... Nature communications 10 (1), 822, 2019 | 115 | 2019 |
Cation-π interactions and their functional roles in membrane proteins DT Infield, A Rasouli, GD Galles, C Chipot, E Tajkhorshid, CA Ahern Journal of molecular biology 433 (17), 167035, 2021 | 90 | 2021 |
Insulin signaling via the PI3-kinase/Akt pathway regulates airway glucose uptake and barrier function in a CFTR-dependent manner SA Molina, HK Moriarty, DT Infield, BR Imhoff, RJ Vance, AH Kim, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (5 …, 2017 | 52 | 2017 |
What biologists want from their chloride reporters–a conversation between chemists and biologists M Zajac, K Chakraborty, S Saha, V Mahadevan, DT Infield, A Accardi, ... Journal of cell science 133 (2), jcs240390, 2020 | 39 | 2020 |
Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR G Cui, KS Rahman, DT Infield, C Kuang, CZ Prince, NA McCarty Journal of General Physiology 144 (2), 159-179, 2014 | 38 | 2014 |
Formulation of meningococcal capsular polysaccharide vaccine-loaded microparticles with robust innate immune recognition RV Ubale, MJ D'souza, DT Infield, NA McCarty, SM Zughaier Journal of microencapsulation 30 (1), 28-41, 2013 | 36 | 2013 |
Cellular encoding of Cy dyes for single-molecule imaging L Leisle, R Chadda, JD Lueck, DT Infield, JD Galpin, V Krishnamani, ... Elife 5, e19088, 2016 | 30 | 2016 |
An ancient CFTR ortholog informs molecular evolution in ABC transporters G Cui, J Hong, YW Chung-Davidson, D Infield, X Xu, J Li, L Simhaev, ... Developmental cell 51 (4), 421-430. e3, 2019 | 21 | 2019 |
Atomic mutagenesis in ion channels with engineered stoichiometry JD Lueck, AL Mackey, DT Infield, JD Galpin, J Li, B Roux, CA Ahern Elife 5, e18976, 2016 | 21 | 2016 |
Rapid evolution of a voltage-gated sodium channel gene in a lineage of electric fish leads to a persistent sodium current A Thompson, DT Infield, AR Smith, GT Smith, CA Ahern, HH Zakon PLoS biology 16 (3), e2004892, 2018 | 20 | 2018 |
Potentiators exert distinct effects on human, murine, and Xenopus CFTR G Cui, N Khazanov, BB Stauffer, DT Infield, BR Imhoff, H Senderowitz, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 311 (2 …, 2016 | 19 | 2016 |
Positioning of extracellular loop 1 affects pore gating of the cystic fibrosis transmembrane conductance regulator DT Infield, G Cui, C Kuang, NA McCarty American Journal of Physiology-Lung Cellular and Molecular Physiology 310 (5 …, 2016 | 19 | 2016 |
The molecular evolution of function in the CFTR chloride channel DT Infield, KM Strickland, A Gaggar, NA McCarty Journal of General Physiology 153 (12), e202012625, 2021 | 18 | 2021 |
Main-chain mutagenesis reveals intrahelical coupling in an ion channel voltage-sensor DT Infield, K Matulef, JD Galpin, K Lam, E Tajkhorshid, CA Ahern, ... Nature communications 9 (1), 5055, 2018 | 18 | 2018 |
Replacing voltage sensor arginines with citrulline provides mechanistic insight into charge versus shape DT Infield, EEL Lee, JD Galpin, GD Galles, F Bezanilla, CA Ahern Journal of General Physiology 150 (7), 1017-1024, 2018 | 15 | 2018 |
Orthogonality of Pyrrolysine tRNA in the Xenopus oocyte DT Infield, JD Lueck, JD Galpin, GD Galles, CA Ahern Scientific reports 8 (1), 5166, 2018 | 14 | 2018 |
Bacterial sphingomyelinase is a state-dependent inhibitor of the cystic fibrosis transmembrane conductance regulator (CFTR) BB Stauffer, G Cui, KA Cottrill, DT Infield, NA McCarty Scientific reports 7 (1), 2931, 2017 | 14 | 2017 |
Tuning phenylalanine fluorination to assess aromatic contributions to protein function and stability in cells GD Galles, DT Infield, CJ Clark, ML Hemshorn, S Manikandan, F Fazan, ... Nature communications 14 (1), 59, 2023 | 12 | 2023 |
Role of a conserved ion-binding site tyrosine in ion selectivity of the Na+/K+ pump K Spontarelli, DT Infield, HN Nielsen, R Holm, VC Young, JD Galpin, ... Journal of General Physiology 154 (7), e202113039, 2022 | 11 | 2022 |