Articles with public access mandates - Mengqian ChenLearn more
Not available anywhere: 2
Hepsin activates prostasin and cleaves the extracellular domain of the epidermal growth factor receptor
M Chen, LM Chen, CY Lin, KX Chai
Molecular and cellular biochemistry 337 (1), 259-266, 2010
Mandates: US National Institutes of Health
ANDROGEN REGULATES THE EXPRESSION OF CRITICAL HEDGEHOG SIGNALING COMPONENTS IN PROSTATE CANCER CELLS
M Chen, M Tanner, AC Levine, E Levina, R Buttyan
The Journal of Urology 181 (4S), 96-96, 2009
Mandates: US National Institutes of Health
Available somewhere: 23
Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities
DC Porter, E Farmaki, S Altilia, GP Schools, DK West, M Chen, BD Chang, ...
Proceedings of the National Academy of Sciences 109 (34), 13799-13804, 2012
Mandates: US National Institutes of Health
CDK8/19 Mediator kinases potentiate induction of transcription by NFκB
M Chen, J Liang, H Ji, Z Yang, S Altilia, B Hu, A Schronce, ...
Proceedings of the National Academy of Sciences 114 (38), 10208-10213, 2017
Mandates: US Department of Defense, US National Institutes of Health, Susan G. Komen
Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer
MSJ McDermott, AA Chumanevich, C Lim, J Liang, M Chen, S Altilia, ...
Oncotarget 8 (8), 12558, 2017
Mandates: US National Institutes of Health, Susan G. Komen
Expression of CDK8 and CDK8-interacting genes as potential biomarkers in breast cancer
E V Broude, B Gyorffy, A A Chumanevich, M Chen, M SJ McDermott, ...
Current cancer drug targets 15 (8), 739-749, 2015
Mandates: US National Institutes of Health, Hungarian Scientific Research Fund
CDK8 selectively promotes the growth of colon cancer metastases in the liver by regulating gene expression of TIMP3 and matrix metalloproteinases
J Liang, M Chen, D Hughes, AA Chumanevich, S Altilia, V Kaza, CU Lim, ...
Cancer research 78 (23), 6594-6606, 2018
Mandates: US National Institutes of Health
Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells
M Chen, M Tanner, AC Levine, E Levina, P Ohouo, R Buttyan
Cell cycle (Georgetown, Tex.) 8 (1), 149, 2009
Mandates: US National Institutes of Health
Therapy-induced developmental reprogramming of prostate cancer cells and acquired therapy resistance
M Nouri, J Caradec, AA Lubik, N Li, BG Hollier, M Takhar, ...
Oncotarget 8 (12), 18949, 2017
Mandates: Canadian Institutes of Health Research, Prostate Cancer Canada
Hedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells
M Chen, MA Feuerstein, E Levina, PS Baghel, RD Carkner, MJ Tanner, ...
Molecular cancer 9, 1-12, 2010
Mandates: US National Institutes of Health
The epidermal growth factor receptor (EGFR) is proteolytically modified by the Matriptase-Prostasin serine protease cascade in cultured epithelial cells
M Chen, LM Chen, CY Lin, KX Chai
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (5), 896-903, 2008
Mandates: US National Institutes of Health
The hedgehog/Gli signaling paradigm in prostate cancer
M Chen, R Carkner, R Buttyan
Expert review of endocrinology & metabolism 6 (3), 453, 2011
Mandates: US National Institutes of Health
The stress response mediator ATF3 represses androgen signaling by binding the androgen receptor
H Wang, M Jiang, H Cui, M Chen, R Buttyan, SW Hayward, T Hai, Z Wang, ...
Molecular and cellular biology, 2012
Mandates: US National Institutes of Health
Systemic toxicity reported for CDK8/19 inhibitors CCT251921 and MSC2530818 is not due to target inhibition
M Chen, J Li, J Liang, ZS Thompson, K Kathrein, EV Broude, IB Roninson
Cells 8 (11), 1413, 2019
Mandates: US National Institutes of Health
Identification of novel cancer therapeutic targets using a designed and pooled shRNA library screen
D Oliver, H Ji, P Liu, A Gasparian, E Gardiner, S Lee, A Zenteno, ...
Scientific reports 7 (1), 43023, 2017
Mandates: US National Institutes of Health
Identifying cancers impacted by CDK8/19
IB Roninson, B Győrffy, ZT Mack, AA Shtil, MS Shtutman, M Chen, ...
Cells 8 (8), 821, 2019
Mandates: US National Institutes of Health, National Office for Research, Development …
Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo
X Ding, AC Sharko, MSJ McDermott, GP Schools, A Chumanevich, H Ji, ...
Proceedings of the National Academy of Sciences 119 (32), e2201073119, 2022
Mandates: US National Institutes of Health, Susan G. Komen
A selective and orally bioavailable quinoline-6-carbonitrile-based inhibitor of CDK8/19 mediator kinase with tumor-enriched pharmacokinetics
L Zhang, C Cheng, J Li, L Wang, AA Chumanevich, DC Porter, A Mindich, ...
Journal of medicinal chemistry 65 (4), 3420-3433, 2022
Mandates: US National Institutes of Health
CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins
M Chen, J Li, L Zhang, L Wang, C Cheng, H Ji, S Altilia, X Ding, G Cai, ...
Nucleic Acids Research 51 (14), 7288-7313, 2023
Mandates: US National Institutes of Health, German Research Foundation
Characterizing CDK8/19 inhibitors through a NFκB-dependent cell-based assay
J Li, H Ji, DC Porter, EV Broude, IB Roninson, M Chen
Cells 8 (10), 1208, 2019
Mandates: US National Institutes of Health
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