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Marlys Koschinsky
Marlys Koschinsky
Scientific & Executive Director, Robarts Research Institute, London, ON
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Lipoprotein (a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement
F Kronenberg, S Mora, ESG Stroes, BA Ference, BJ Arsenault, L Berglund, ...
European heart journal 43 (39), 3925-3946, 2022
5762022
Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress
TA Seimon, MJ Nadolski, X Liao, J Magallon, M Nguyen, NT Feric, ...
Cell metabolism 12 (5), 467-482, 2010
5582010
Oxidized phospholipids on lipoprotein (a) elicit arterial wall inflammation and an inflammatory monocyte response in humans
FM van der Valk, S Bekkering, J Kroon, C Yeang, J Van den Bossche, ...
Circulation 134 (8), 611-624, 2016
5322016
Use of Lipoprotein (a) in clinical practice: A biomarker whose time has come. A scientific statement from the National Lipid Association
DP Wilson, TA Jacobson, PH Jones, ML Koschinsky, CJ McNeal, ...
Journal of clinical lipidology 13 (3), 374-392, 2019
4822019
NHLBI working group recommendations to reduce lipoprotein (a)-mediated risk of cardiovascular disease and aortic stenosis
S Tsimikas, S Fazio, KC Ferdinand, HN Ginsberg, ML Koschinsky, ...
Journal of the American College of Cardiology 71 (2), 177-192, 2018
4502018
Report of the National Heart, Lung, and Blood Institute Workshop on Lipoprotein (a) and Cardiovascular Disease: recent advances and future directions
SM Marcovina, ML Koschinsky, JJ Albers, S Skarlatos
Clinical chemistry 49 (11), 1785-1796, 2003
4072003
Effect of the number of apolipoprotein (a) kringle 4 domains on immunochemical measurements of lipoprotein (a)
SM Marcovina, JJ Albers, B Gabel, ML Koschinsky, VP Gaur
Clinical chemistry 41 (2), 246-255, 1995
4021995
Lipoprotein (a): a genetically determined, causal, and prevalent risk factor for atherosclerotic cardiovascular disease: a scientific statement from the American Heart Association
G Reyes-Soffer, HN Ginsberg, L Berglund, PB Duell, SP Heffron, ...
Arteriosclerosis, Thrombosis, and vascular biology 42 (1), e48-e60, 2022
3742022
Lipoprotein (a) and oxidized phospholipids promote valve calcification in patients with aortic stenosis
KH Zheng, S Tsimikas, T Pawade, J Kroon, WSA Jenkins, MK Doris, ...
Journal of the American College of Cardiology 73 (17), 2150-2162, 2019
2762019
Lipoprotein (a) levels and the risk of myocardial infarction among 7 ethnic groups
G Paré, A Çaku, M McQueen, SS Anand, E Enas, R Clarke, MB Boffa, ...
Circulation 139 (12), 1472-1482, 2019
2662019
Lipoprotein (a): truly a direct prothrombotic factor in cardiovascular disease?
MB Boffa, ML Koschinsky
Journal of lipid research 57 (5), 745-757, 2016
2642016
Identification of the cysteine residue in apolipoprotein (a) that mediates extracellular coupling with apolipoprotein B-100.
ML Koschinsky, GP Cote, B Gabel, YY van der Hoek
Journal of Biological Chemistry 268 (26), 19819-19825, 1993
2571993
Autotaxin derived from lipoprotein (a) and valve interstitial cells promotes inflammation and mineralization of the aortic valve
R Bouchareb, A Mahmut, MJ Nsaibia, MC Boulanger, A Dahou, JL Lépine, ...
Circulation 132 (8), 677-690, 2015
2552015
Lipoprotein (a) as a risk factor for coronary artery disease
SM Marcovina, ML Koschinsky
The American journal of cardiology 82 (12), 57U-66U, 1998
2551998
Structure-function relationships in apolipoprotein (a): insights into lipoprotein (a) assembly and pathogenicity
ML Koschinsky, SM Marcovina
Current opinion in lipidology 15 (2), 167-174, 2004
2542004
Lipoprotein (a) catabolism is regulated by proprotein convertase subtilisin/kexin type 9 through the low density lipoprotein receptor
R Romagnuolo, CA Scipione, MB Boffa, SM Marcovina, NG Seidah, ...
Journal of Biological Chemistry 290 (18), 11649-11662, 2015
2382015
Determinants of binding of oxidized phospholipids on apolipoprotein (a) and lipoprotein (a) 1
G Leibundgut, C Scipione, H Yin, M Schneider, MB Boffa, S Green, ...
Journal of lipid research 54 (10), 2815-2830, 2013
2352013
Two naturally occurring variants of TAFI (Thr-325 and Ile-325) differ substantially with respect to thermal stability and antifibrinolytic activity of the enzyme
M Schneider, M Boffa, R Stewart, M Rahman, M Koschinsky, M Nesheim
Journal of Biological Chemistry 277 (2), 1021-1030, 2002
2332002
The apolipoprotein (a) kringle IV repeats which differ from the major repeat kringle are present in variably-sized isoforms
YY Hoek, ME Wittekoek, U Beisiegel, JJP Kastelein, ML Koschinsky
Human molecular genetics 2 (4), 361-366, 1993
2311993
Lipoprotein (a) as a risk factor for atherosclerosis and thrombosis: mechanistic insights from animal models
MB Boffa, SM Marcovina, ML Koschinsky
Clinical biochemistry 37 (5), 333-343, 2004
2222004
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