Molecular docking in modern drug discovery: Principles and recent applications A Sethi, K Joshi, K Sasikala, M Alvala Drug discovery and development-new advances 2, 1-21, 2019 | 207 | 2019 |
Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells S Shrivastava, P Kulkarni, D Thummuri, MK Jeengar, VGM Naidu, ... Apoptosis 19, 1148-1164, 2014 | 153 | 2014 |
Antimicrobial peptides: a promising therapeutic strategy in tackling antimicrobial resistance R Nuti, NS Goud, AP Saraswati, R Alvala, M Alvala Current medicinal chemistry 24 (38), 4303-4314, 2017 | 118 | 2017 |
Inhibition of SIRT1 by a small molecule induces apoptosis in breast cancer cells Alinakhi, P Talukdar, AM Kalle, M Alvala, J Badiger, Sachchidanand Biochem. Biophys. Res. Commun 401, 13, 2010 | 106 | 2010 |
Inhibition of SIRT1 by a small molecule induces apoptosis in breast cancer cells AM Kalle, A Mallika, J Badiger, TP Alinakhi, Sachchidanand Biochem Biophys. Res. Commun 401, 13-19, 2010 | 101 | 2010 |
Inhibition of SIRT1 by a small molecule induces apoptosis in breast cancer cells AM Kalle, A Mallika, J Badiger, P Talukdar Biochemical and biophysical research communications 401 (1), 13-19, 2010 | 100 | 2010 |
Synthesis and biological evaluation of coumarin-1, 3, 4-oxadiazole hybrids as selective carbonic anhydrase IX and XII inhibitors SG Narella, MG Shaik, A Mohammed, M Alvala, A Angeli, CT Supuran Bioorganic chemistry 87, 765-772, 2019 | 55 | 2019 |
Ethylenediamine diacetate (EDDA) mediated synthesis of aurones under ultrasound: Their evaluation as inhibitors of SIRT1 K Manjulatha, S Srinivas, N Mulakayala, D Rambabu, M Prabhakar, ... Bioorganic & medicinal chemistry letters 22 (19), 6160-6165, 2012 | 55 | 2012 |
Synthesis and biological evaluation of imidazo [1, 5-a] pyridine-benzimidazole hybrids as inhibitors of both tubulin polymerization and PI3K/Akt pathway A Kamal, AVS Rao, VL Nayak, NVS Reddy, K Swapna, G Ramakrishna, ... Organic & Biomolecular Chemistry 12 (48), 9864-9880, 2014 | 51 | 2014 |
Antiproliferative activity and standardization of Tecomella undulata bark extract on K562 cells A Ravi, A Mallika, V Sama, AS Begum, RS Khan, BM Reddy Journal of Ethnopharmacology 137 (3), 1353-1359, 2011 | 51 | 2011 |
Synthesis and biological evaluation of morpholines linked coumarin–triazole hybrids as anticancer agents NS Goud, V Pooladanda, GS Mahammad, P Jakkula, S Gatreddi, ... Chemical Biology & Drug Design 94 (5), 1919-1929, 2019 | 50 | 2019 |
An updated patent review of galectin-1 and galectin-3 inhibitors and their potential therapeutic applications (2016–present) A Sethi, S Sanam, R Alvala, M Alvala Expert Opinion on Therapeutic Patents 31 (8), 709-721, 2021 | 49 | 2021 |
Identification and structure–activity relationship study of carvacrol derivatives as Mycobacterium tuberculosis chorismate mutase inhibitors DS Reshma Alokam, Variam Ullas Jeankumar J Enzyme Inhib Med Chem., 2013 | 47* | 2013 |
Novel acridinedione derivatives: design, synthesis, SIRT1 enzyme and tumor cell growth inhibition studies M Alvala, S Bhatnagar, A Ravi, VU Jeankumar, TH Manjashetty, ... Bioorganic & medicinal chemistry letters 22 (9), 3256-3260, 2012 | 47 | 2012 |
Mycobacterium tuberculosis chorismate mutase: A potential target for TB M Khanapur, M Alvala, M Prabhakar, KS Kumar, RK Edwin, PS Saranya, ... Bioorganic & medicinal chemistry 25 (6), 1725-1736, 2017 | 45 | 2017 |
Synthesis and biological evaluation of pyrrolo [2, 3-b] pyridine analogues as antiproliferative agents and their interaction with calf thymus DNA S Narva, S Chitti, BR Bala, M Alvala, N Jain, VGCS Kondapalli European Journal of Medicinal Chemistry 114, 220-231, 2016 | 44 | 2016 |
Anticancer activity of Pupalia lappacea on chronic myeloid leukemia K562 cells A Ravi, M Alvala, V Sama, AM Kalle, VK Irlapati, BM Reddy DARU Journal of Pharmaceutical Sciences 20, 1-10, 2012 | 44 | 2012 |
Transition metal mediated construction of pyrrole ring on 2, 3-dihydroquinolin-4 (1H)-one: synthesis and pharmacological evaluation of novel tricyclic heteroarenes M Layek, AVD Rao, M Alvala, MK Arunasree, A Islam, K Mukkanti, J Iqbal, ... Organic & Biomolecular Chemistry 9 (4), 1004-1007, 2011 | 43 | 2011 |
Design, synthesis and evaluation of small molecule reactive oxygen species generators as selective Mycobacterium tuberculosis inhibitors AT Dharmaraja, M Alvala, D Sriram, P Yogeeswari, H Chakrapani Chemical communications 48 (83), 10325-10327, 2012 | 42 | 2012 |
Molecular dynamic simulations reveal suboptimal binding of salbutamol in T164I variant of β2 adrenergic receptor S Bandaru, M Alvala, A Nayarisseri, S Sharda, H Goud, HP Mundluru, ... PloS one 12 (10), e0186666, 2017 | 41 | 2017 |