Succinate is an inflammatory signal that induces IL-1β through HIF-1α GM Tannahill, AM Curtis, J Adamik, EM Palsson-McDermott, ... Nature 496 (7444), 238-242, 2013 | 3600 | 2013 |
Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Δ12, 14-prostaglandin J2 K Itoh, M Mochizuki, Y Ishii, T Ishii, T Shibata, Y Kawamoto, V Kelly, ... Molecular and cellular biology, 2004 | 498 | 2004 |
Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase, the glutathione S … VP Kelly, EM Ellis, MM Manson, SA Chanas, GJ Moffat, R McLeod, ... Cancer Research 60 (4), 957-969, 2000 | 190 | 2000 |
Malonylation of GAPDH is an inflammatory signal in macrophages S Galván-Peña, RG Carroll, C Newman, EC Hinchy, ... Nature communications 10 (1), 338, 2019 | 167 | 2019 |
The queuine micronutrient: charting a course from microbe to man C Fergus, D Barnes, MA Alqasem, VP Kelly Nutrients 7 (4), 2897-2929, 2015 | 149 | 2015 |
High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress T Arai, VP Kelly, O Minowa, T Noda, S Nishimura Carcinogenesis 23 (12), 2005-2010, 2002 | 134 | 2002 |
CdTe quantum dot/dye hybrid system as photosensitizer for photodynamic therapy A Rakovich, D Savateeva, T Rakovich, JF Donegan, YP Rakovich, V Kelly, ... Nanoscale research letters 5, 753-760, 2010 | 118 | 2010 |
Structural snapshots of the KMSKS loop rearrangement for amino acid activation by bacterial tyrosyl-tRNA synthetase T Kobayashi, T Takimura, R Sekine, K Vincent, K Kamata, K Sakamoto, ... Journal of molecular biology 346 (1), 105-117, 2005 | 106 | 2005 |
Deletion of the Selenocysteine tRNA Gene in Macrophages and Liver Results in Compensatory Gene Induction of Cytoprotective Enzymes by Nrf2*♦ T Suzuki, VP Kelly, H Motohashi, O Nakajima, S Takahashi, S Nishimura, ... Journal of Biological Chemistry 283 (4), 2021-2030, 2008 | 103 | 2008 |
The study using wild-type and Ogg1 knockout mice exposed to potassium bromate shows no tumor induction despite an extensive accumulation of 8-hydroxyguanine in kidney DNA T Arai, VP Kelly, O Minowa, T Noda, S Nishimura Toxicology 221 (2-3), 179-186, 2006 | 92 | 2006 |
Queuosine deficiency in eukaryotes compromises tyrosine production through increased tetrahydrobiopterin oxidation T Rakovich, C Boland, I Bernstein, VM Chikwana, D Iwata-Reuyl, VP Kelly Journal of Biological Chemistry 286 (22), 19354-19363, 2011 | 86 | 2011 |
Queuosine formation in eukaryotic tRNA occurs via a mitochondria-localized heteromeric transglycosylase C Boland, P Hayes, I Santa-Maria, S Nishimura, VP Kelly Journal of Biological Chemistry 284 (27), 18218-18227, 2009 | 82 | 2009 |
Cell proliferation in liver of Mmh/Ogg1-deficient mice enhances mutation frequency because of the presence of 8-hydroxyguanine in DNA T Arai, VP Kelly, K Komoro, O Minowa, T Noda, S Nishimura Cancer research 63 (14), 4287-4292, 2003 | 82 | 2003 |
Characterization of the human tRNA-guanine transglycosylase: confirmation of the heterodimeric subunit structure YC Chen, VP Kelly, SV Stachura, GA Garcia Rna 16 (5), 958-968, 2010 | 80 | 2010 |
Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia Y Kawatani, T Suzuki, R Shimizu, VP Kelly, M Yamamoto Blood, The Journal of the American Society of Hematology 117 (3), 986-996, 2011 | 74 | 2011 |
Queuine links translational control in eukaryotes to a micronutrient from bacteria M Müller, C Legrand, F Tuorto, VP Kelly, Y Atlasi, F Lyko, ... Nucleic acids research 47 (7), 3711-3727, 2019 | 67 | 2019 |
The “speed gene” effect of myostatin arises in Thoroughbred horses due to a promoter proximal SINE insertion MF Rooney, EW Hill, VP Kelly, RK Porter PloS one 13 (10), e0205664, 2018 | 56 | 2018 |
Novel homodimeric and heterodimeric rat γ-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteins VP Kelly, PJ Sherratt, DH Crouch, JD Hayes Biochemical Journal 366 (3), 847-861, 2002 | 55 | 2002 |
Structural basis of nonnatural amino acid recognition by an engineered aminoacyl-tRNA synthetase for genetic code expansion T Kobayashi, K Sakamoto, T Takimura, R Sekine, K Vincent, K Kamata, ... Proceedings of the National Academy of Sciences 102 (5), 1366-1371, 2005 | 48 | 2005 |
Purification from rat liver of a novel constitutively expressed member of the aldo-keto reductase 7 family that is widely distributed in extrahepatic tissues VP Kelly, LS Ireland, EM Ellis, JD Hayes Biochemical Journal 348 (2), 389-400, 2000 | 41 | 2000 |