Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo DJ Apicco, PEA Ash, B Maziuk, C LeBlang, M Medalla, A Al Abdullatif, ... Nature neuroscience 21 (1), 72-80, 2018 | 226 | 2018 |
Database of traditional Chinese medicine and its application to studies of mechanism and to prescription validation X Chen, H Zhou, YB Liu, JF Wang, H Li, CY Ung, LY Han, ZW Cao, ... British journal of pharmacology 149 (8), 1092-1103, 2006 | 225 | 2006 |
Effect of selection of molecular descriptors on the prediction of blood− brain barrier penetrating and nonpenetrating agents by statistical learning methods H Li, CW Yap, CY Ung, Y Xue, ZW Cao, YZ Chen Journal of Chemical Information and Modeling 45 (5), 1376-1384, 2005 | 200 | 2005 |
Prediction of potential toxicity and side effect protein targets of a small molecule by a ligand–protein inverse docking approach YZ Chen, CY Ung Journal of Molecular Graphics and Modelling 20 (3), 199-218, 2001 | 190 | 2001 |
Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation CY Ung, SH Lam, MM Hlaing, CL Winata, S Korzh, S Mathavan, Z Gong Bmc Genomics 11, 1-14, 2010 | 175 | 2010 |
Toxicogenomic and phenotypic analyses of bisphenol-A early-life exposure toxicity in zebrafish SH Lam, MM Hlaing, X Zhang, C Yan, Z Duan, L Zhu, CY Ung, ... PloS one 6 (12), e28273, 2011 | 163 | 2011 |
Classification of a Diverse Set of Tetrahymena pyriformis Toxicity Chemical Compounds from Molecular Descriptors by Statistical Learning Methods Y Xue, H Li, CY Ung, CW Yap, YZ Chen Chemical research in toxicology 19 (8), 1030-1039, 2006 | 101 | 2006 |
Prediction of genotoxicity of chemical compounds by statistical learning methods H Li, CY Ung, CW Yap, Y Xue, ZR Li, ZW Cao, YZ Chen Chemical research in toxicology 18 (6), 1071-1080, 2005 | 100 | 2005 |
Can an in silico drug-target search method be used to probe potential mechanisms of medicinal plant ingredients? X Chen, CY Ung, Y Chen Natural Product Reports 20 (4), 432-444, 2003 | 99 | 2003 |
LMO1 synergizes with MYCN to promote neuroblastoma initiation and metastasis S Zhu, X Zhang, N Weichert-Leahey, Z Dong, C Zhang, G Lopez, T Tao, ... Cancer cell 32 (3), 310-323. e5, 2017 | 97 | 2017 |
Are herb-pairs of traditional Chinese medicine distinguishable from others? Pattern analysis and artificial intelligence classification study of traditionally defined herbal … CY Ung, H Li, ZW Cao, YX Li, YZ Chen Journal of Ethnopharmacology 111 (2), 371-377, 2007 | 95 | 2007 |
Computer prediction of allergen proteins from sequence-derived protein structural and physicochemical properties J Cui, LY Han, H Li, CY Ung, ZQ Tang, CJ Zheng, ZW Cao, YZ Chen Molecular immunology 44 (4), 514-520, 2007 | 92 | 2007 |
Machine learning approaches for predicting compounds that interact with therapeutic and ADMET related proteins H Li, CW Yap, CY Ung, Y Xue, ZR Li, LY Han, HH Lin, YZ Chen Journal of pharmaceutical sciences 96 (11), 2838-2860, 2007 | 91 | 2007 |
In silico prediction of pregnane x receptor activators by machine learning approache CY Ung, H Li, CW Yap, YZ Chen Molecular pharmacology 71 (1), 158-168, 2007 | 90 | 2007 |
Dysregulation of RNA splicing in tauopathies DJ Apicco, C Zhang, B Maziuk, L Jiang, HI Ballance, S Boudeau, C Ung, ... Cell reports 29 (13), 4377-4388. e4, 2019 | 64 | 2019 |
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods H Li, CY Ung, CW Yap, Y Xue, ZR Li, YZ Chen Journal of Molecular Graphics and Modelling 25 (3), 313-323, 2006 | 57 | 2006 |
Neuroblastoma, a paradigm for big data science in pediatric oncology BM Salazar, EA Balczewski, CY Ung, S Zhu International journal of molecular sciences 18 (1), 37, 2016 | 56 | 2016 |
Computer automated prediction of potential therapeutic and toxicity protein targets of bioactive compounds from Chinese medicinal plants YZ Chen, CY Ung The American journal of Chinese medicine 30 (01), 139-154, 2002 | 52 | 2002 |
Machine learning-assisted network inference approach to identify a new class of genes that coordinate the functionality of cancer networks M Ghanat Bari, CY Ung, C Zhang, S Zhu, H Li Scientific reports 7 (1), 6993, 2017 | 50 | 2017 |
Simulation of the regulation of EGFR endocytosis and EGFR-ERK signaling by endophilin-mediated RhoA-EGFR crosstalk CY Ung, H Li, XH Ma, J Jia, BW Li, BC Low, YZ Chen FEBS letters 582 (15), 2283-2290, 2008 | 50 | 2008 |