Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes T Jourdan, G Godlewski, R Cinar, A Bertola, G Szanda, J Liu, J Tam, ... Nature medicine 19 (9), 1132-1140, 2013 | 401 | 2013 |
Crystal structure of the human cannabinoid receptor CB2 X Li, T Hua, K Vemuri, JH Ho, Y Wu, L Wu, P Popov, O Benchama, ... Cell 176 (3), 459-467. e13, 2019 | 379 | 2019 |
Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance J Tam, R Cinar, J Liu, G Godlewski, D Wesley, T Jourdan, G Szanda, ... Cell metabolism 16 (2), 167-179, 2012 | 358 | 2012 |
Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity O Gunduz-Cinar, KP MacPherson, R Cinar, J Gamble-George, K Sugden, ... Molecular psychiatry 18 (7), 813-823, 2013 | 339 | 2013 |
Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy M Rajesh, S Bátkai, M Kechrid, P Mukhopadhyay, WS Lee, B Horváth, ... Diabetes 61 (3), 716-727, 2012 | 275 | 2012 |
Endocannabinoids in liver disease J Tam, J Liu, B Mukhopadhyay, R Cinar, G Godlewski, G Kunos Hepatology 53 (1), 346-355, 2011 | 229 | 2011 |
Chronic alcohol produces neuroadaptations to prime dorsal striatal learning L DePoy, R Daut, JL Brigman, K MacPherson, N Crowley, ... Proceedings of the National Academy of Sciences 110 (36), 14783-14788, 2013 | 211 | 2013 |
Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasingde novosynthesis of long-chain ceramides R Cinar, G Godlewski, J Liu, J Tam, T Jourdan, B Mukhopadhyay, ... Hepatology 59 (1), 143-153, 2014 | 164 | 2014 |
Stratification of hepatocellular carcinoma patients based on acetate utilization E Björnson, B Mukhopadhyay, A Asplund, N Pristovsek, R Cinar, ... Cell reports 13 (9), 2014-2026, 2015 | 139 | 2015 |
Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy T Jourdan, G Szanda, AZ Rosenberg, J Tam, BJ Earley, G Godlewski, ... Proceedings of the National Academy of Sciences 111 (50), E5420-E5428, 2014 | 136 | 2014 |
Network analyses identify liver‐specific targets for treating liver diseases S Lee, C Zhang, Z Liu, M Klevstig, B Mukhopadhyay, M Bergentall, ... Molecular systems biology 13 (8), 938, 2017 | 123 | 2017 |
The therapeutic potential of second and third generation CB1R antagonists R Cinar, MR Iyer, G Kunos Pharmacology & therapeutics 208, 107477, 2020 | 115 | 2020 |
Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver B Mukhopadhyay, R Cinar, S Yin, J Liu, J Tam, G Godlewski, ... Proceedings of the National Academy of Sciences 108 (15), 6323-6328, 2011 | 109 | 2011 |
Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects G Godlewski, SO Alapafuja, S Bátkai, SP Nikas, R Cinar, L Offertáler, ... Chemistry & biology 17 (11), 1256-1266, 2010 | 99 | 2010 |
Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms B Mukhopadhyay, K Schuebel, P Mukhopadhyay, R Cinar, G Godlewski, ... Hepatology 61 (5), 1615-1626, 2015 | 94 | 2015 |
β‐Caryophyllene protects against alcoholic steatohepatitis by attenuating inflammation and metabolic dysregulation in mice ZV Varga, C Matyas, K Erdelyi, R Cinar, D Nieri, A Chicca, BT Nemeth, ... British journal of pharmacology 175 (2), 320-334, 2018 | 93 | 2018 |
National institutes of health consensus development project on criteria for clinical trials in chronic graft-versus-Host disease: IV. the 2020 highly morbid forms report D Wolff, V Radojcic, R Lafyatis, R Cinar, RK Rosenstein, EW Cowen, ... Transplantation and cellular therapy 27 (10), 817-835, 2021 | 92 | 2021 |
Proximal tubular cannabinoid-1 receptor regulates obesity-induced CKD S Udi, L Hinden, B Earley, A Drori, N Reuveni, R Hadar, R Cinar, ... Journal of the American Society of Nephrology 28 (12), 3518-3532, 2017 | 92 | 2017 |
Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase J Liu, R Cinar, K Xiong, G Godlewski, T Jourdan, Y Lin, JM Ntambi, ... Proceedings of the National Academy of Sciences 110 (47), 18832-18837, 2013 | 82 | 2013 |
Glutamate signaling in hepatic stellate cells drives alcoholic steatosis WM Choi, HH Kim, MH Kim, R Cinar, HS Yi, HS Eun, SH Kim, YJ Choi, ... Cell metabolism 30 (5), 877-889. e7, 2019 | 79 | 2019 |