The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity C Zhu, AC Anderson, A Schubart, H Xiong, J Imitola, SJ Khoury, ... Nature immunology 6 (12), 1245-1252, 2005 | 2249 | 2005 |
Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity K Sakuishi, L Apetoh, JM Sullivan, BR Blazar, VK Kuchroo, AC Anderson Journal of Experimental Medicine 207 (10), 2187-2194, 2010 | 2216 | 2010 |
Lag-3, Tim-3, and TIGIT: co-inhibitory receptors with specialized functions in immune regulation AC Anderson, N Joller, VK Kuchroo Immunity 44 (5), 989-1004, 2016 | 2008 | 2016 |
Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection HT Jin, AC Anderson, WG Tan, EE West, SJ Ha, K Araki, GJ Freeman, ... Proceedings of the National Academy of Sciences 107 (33), 14733-14738, 2010 | 999 | 2010 |
Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells AC Anderson, DE Anderson, L Bregoli, WD Hastings, N Kassam, C Lei, ... Science 318 (5853), 1141-1143, 2007 | 819 | 2007 |
TIM3 comes of age as an inhibitory receptor Y Wolf, AC Anderson, VK Kuchroo Nature Reviews Immunology 20 (3), 173-185, 2020 | 764 | 2020 |
Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia Q Zhou, ME Munger, RG Veenstra, BJ Weigel, M Hirashima, DH Munn, ... Blood, The Journal of the American Society of Hematology 117 (17), 4501-4510, 2011 | 754 | 2011 |
CEACAM1 regulates TIM-3-mediated tolerance and exhaustion YH Huang, C Zhu, Y Kondo, AC Anderson, A Gandhi, A Russell, ... Nature 517 (7534), 386-390, 2015 | 673 | 2015 |
TIGIT predominantly regulates the immune response via regulatory T cells S Kurtulus, K Sakuishi, SF Ngiow, N Joller, DJ Tan, MWL Teng, MJ Smyth, ... The Journal of clinical investigation 125 (11), 4053-4062, 2015 | 571 | 2015 |
Checkpoint blockade immunotherapy induces dynamic changes in PD-1− CD8+ tumor-infiltrating T cells S Kurtulus, A Madi, G Escobar, M Klapholz, J Nyman, E Christian, ... Immunity 50 (1), 181-194. e6, 2019 | 559 | 2019 |
Role of Th1 and Th17 cells in organ-specific autoimmunity V Dardalhon, T Korn, VK Kuchroo, AC Anderson Journal of autoimmunity 31 (3), 252-256, 2008 | 554 | 2008 |
CD11b+ Ly-6Chi suppressive monocytes in experimental autoimmune encephalomyelitis B Zhu, Y Bando, S Xiao, K Yang, AC Anderson, VK Kuchroo, SJ Khoury The Journal of Immunology 179 (8), 5228-5237, 2007 | 474 | 2007 |
T cell response in experimental autoimmune encephalomyelitis (EAE): role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire VK Kuchroo, AC Anderson, H Waldner, M Munder, E Bettelli, ... Annual review of immunology 20 (1), 101-123, 2002 | 445 | 2002 |
TIGIT and CD 96: new checkpoint receptor targets for cancer immunotherapy WC Dougall, S Kurtulus, MJ Smyth, AC Anderson Immunological reviews 276 (1), 112-120, 2017 | 440 | 2017 |
A distinct gene module for dysfunction uncoupled from activation in tumor-infiltrating T cells M Singer, C Wang, L Cong, ND Marjanovic, MS Kowalczyk, H Zhang, ... Cell 166 (6), 1500-1511. e9, 2016 | 419 | 2016 |
Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion M Rangachari, C Zhu, K Sakuishi, S Xiao, J Karman, A Chen, M Angin, ... Nature medicine 18 (9), 1394-1400, 2012 | 410 | 2012 |
Induction and transcriptional regulation of the co-inhibitory gene module in T cells N Chihara, A Madi, T Kondo, H Zhang, N Acharya, M Singer, J Nyman, ... Nature 558 (7710), 454-459, 2018 | 404 | 2018 |
Reversal of NK-cell exhaustion in advanced melanoma by Tim-3 blockade IP da Silva, A Gallois, S Jimenez-Baranda, S Khan, AC Anderson, ... Cancer immunology research 2 (5), 410-422, 2014 | 398 | 2014 |
Spatially organized multicellular immune hubs in human colorectal cancer K Pelka, M Hofree, JH Chen, S Sarkizova, JD Pirl, V Jorgji, A Bejnood, ... Cell 184 (18), 4734-4752. e20, 2021 | 380 | 2021 |
Tim-3: an emerging target in the cancer immunotherapy landscape AC Anderson Cancer immunology research 2 (5), 393-398, 2014 | 348 | 2014 |