Articles with public access mandates - Eugene ShakhnovichLearn more
Not available anywhere: 1
A tale of two tails: The importance of unstructured termini in the aggregation pathway of β2‐microglobulin
RJS Loureiro, D Vila‐Viçosa, M Machuqueiro, EI Shakhnovich, ...
Proteins: Structure, Function, and Bioinformatics 85 (11), 2045-2057, 2017
Mandates: Fundação para a Ciência e a Tecnologia, Portugal
Available somewhere: 111
Common activation mechanism of class A GPCRs
Q Zhou, D Yang, M Wu, Y Guo, W Guo, L Zhong, X Cai, A Dai, W Jang, ...
Elife 8, e50279, 2019
Mandates: US National Institutes of Health, Chinese Academy of Sciences, National …
The interface of protein structure, protein biophysics, and molecular evolution
DA Liberles, SA Teichmann, I Bahar, U Bastolla, J Bloom, ...
Protein Science 21 (6), 769-785, 2012
Mandates: US National Institutes of Health
Accelerating high-throughput virtual screening through molecular pool-based active learning
DE Graff, EI Shakhnovich, CW Coley
Chemical science 12 (22), 7866-7881, 2021
Mandates: US National Institutes of Health
A biophysical protein folding model accounts for most mutational fitness effects in viruses
CS Wylie, EI Shakhnovich
Proceedings of the National Academy of Sciences 108 (24), 9916-9921, 2011
Mandates: US National Institutes of Health
Protein quality control acts on folding intermediates to shape the effects of mutations on organismal fitness
S Bershtein, W Mu, AWR Serohijos, J Zhou, EI Shakhnovich
Molecular cell 49 (1), 133-144, 2013
Mandates: US National Institutes of Health
Biophysical principles predict fitness landscapes of drug resistance
JV Rodrigues, S Bershtein, A Li, ER Lozovsky, DL Hartl, EI Shakhnovich
Proceedings of the National Academy of Sciences 113 (11), E1470-E1478, 2016
Mandates: US National Institutes of Health
All-atom model for stabilization of α-helical structure in peptides by hydrocarbon staples
PS Kutchukian, JS Yang, GL Verdine, EI Shakhnovich
Journal of the American Chemical Society 131 (13), 4622-4627, 2009
Mandates: US National Institutes of Health
Dynamic metastable long-living droplets formed by sticker-spacer proteins
S Ranganathan, EI Shakhnovich
Elife 9, e56159, 2020
Mandates: US National Institutes of Health
Constraints imposed by non‐functional protein–protein interactions on gene expression and proteome size
J Zhang, S Maslov, EI Shakhnovich
Molecular systems biology 4 (1), 210, 2008
Mandates: US National Institutes of Health
Soluble oligomerization provides a beneficial fitness effect on destabilizing mutations
S Bershtein, W Mu, EI Shakhnovich
Proceedings of the National Academy of Sciences 109 (13), 4857-4862, 2012
Mandates: US National Institutes of Health
Topology of protein interaction network shapes protein abundances and strengths of their functional and nonspecific interactions
M Heo, S Maslov, E Shakhnovich
Proceedings of the National Academy of Sciences 108 (10), 4258-4263, 2011
Mandates: US National Institutes of Health
Protein biophysics explains why highly abundant proteins evolve slowly
AWR Serohijos, Z Rimas, EI Shakhnovich
Cell reports 2 (2), 249-256, 2012
Mandates: US National Institutes of Health
Evidence of evolutionary selection for cotranslational folding
WM Jacobs, EI Shakhnovich
Proceedings of the National Academy of Sciences 114 (43), 11434-11439, 2017
Mandates: US National Institutes of Health
Differential enzyme flexibility probed using solid-state nanopores
R Hu, JV Rodrigues, P Waduge, H Yamazaki, B Cressiot, Y Chishti, ...
ACS nano 12 (5), 4494-4502, 2018
Mandates: US National Science Foundation, US National Institutes of Health, National …
Merging molecular mechanism and evolution: theory and computation at the interface of biophysics and evolutionary population genetics
AWR Serohijos, EI Shakhnovich
Current opinion in structural biology 26, 84-91, 2014
Mandates: US National Institutes of Health
Understanding protein evolution: from protein physics to Darwinian selection
KB Zeldovich, EI Shakhnovich
Annu. Rev. Phys. Chem. 59 (1), 105-127, 2008
Mandates: US National Institutes of Health
Protein homeostasis imposes a barrier on functional integration of horizontally transferred genes in bacteria
S Bershtein, AWR Serohijos, S Bhattacharyya, M Manhart, JM Choi, W Mu, ...
PLoS genetics 11 (10), e1005612, 2015
Mandates: US National Institutes of Health
Optimality of mutation and selection in germinal centers
J Zhang, EI Shakhnovich
PLoS computational biology 6 (6), e1000800, 2010
Mandates: US National Institutes of Health
An Internal Disulfide Locks a Misfolded Aggregation-Prone Intermediate in Cataract-Linked Mutants of Human Gamma-D Crystallin
E Serebryany, JC Woodard, BV Adkar, M Shabab, JA King, ...
Biophysical Journal 112 (3), 167a-168a, 2017
Mandates: US National Institutes of Health
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