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Available somewhere: 28
Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2α) dephosphorylation in mammalian development
HP Harding, Y Zhang, D Scheuner, JJ Chen, RJ Kaufman, D Ron
Proceedings of the national academy of sciences 106 (6), 1832-1837, 2009
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Graphene oxide induces toll-like receptor 4 (TLR4)-dependent necrosis in macrophages
G Qu, S Liu, S Zhang, L Wang, X Wang, B Sun, N Yin, X Gao, T Xia, ...
ACS nano 7 (7), 5732-5745, 2013
Mandates: US National Institutes of Health
Heme-regulated eIF2α kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis
RNVS Suragani, RS Zachariah, JG Velazquez, S Liu, CW Sun, ...
Blood, The Journal of the American Society of Hematology 119 (22), 5276-5284, 2012
Mandates: US National Institutes of Health
The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling
M Abdel-Nour, LAM Carneiro, J Downey, J Tsalikis, A Outlioua, D Prescott, ...
Science 365 (6448), eaaw4144, 2019
Mandates: US National Institutes of Health, Canadian Institutes of Health Research …
Translational control by heme-regulated eIF2α kinase during erythropoiesis
JJ Chen
Current opinion in hematology 21 (3), 172-178, 2014
Mandates: US National Institutes of Health
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation
A Basak, M Munschauer, CA Lareau, KE Montbleau, JC Ulirsch, ...
Nature genetics 52 (2), 138-145, 2020
Mandates: US National Institutes of Health
ATF4 regulates CD4+ T cell immune responses through metabolic reprogramming
X Yang, R Xia, C Yue, W Zhai, W Du, Q Yang, H Cao, X Chen, D Obando, ...
Cell reports 23 (6), 1754-1766, 2018
Mandates: US National Institutes of Health, National Natural Science Foundation of China
Heme-regulated eIF2α kinase in erythropoiesis and hemoglobinopathies
JJ Chen, S Zhang
Blood, The Journal of the American Society of Hematology 134 (20), 1697-1707, 2019
Mandates: US National Institutes of Health
HRI coordinates translation by eIF2αP and mTORC1 to mitigate ineffective erythropoiesis in mice during iron deficiency
S Zhang, A Macias-Garcia, J Velazquez, E Paltrinieri, RJ Kaufman, ...
Blood, The Journal of the American Society of Hematology 131 (4), 450-461, 2018
Mandates: US National Institutes of Health
Regulation of globin-heme balance in Diamond-Blackfan anemia by HSP70/GATA1
S Rio, M Gastou, N Karboul, R Derman, T Suriyun, H Manceau, T Leblanc, ...
Blood, The Journal of the American Society of Hematology 133 (12), 1358-1370, 2019
Mandates: US National Institutes of Health, Agence Nationale de la Recherche
Haem‐regulated eIF2α kinase is necessary for adaptive gene expression in erythroid precursors under the stress of iron deficiency
S Liu, S Bhattacharya, A Han, RNVS Suragani, W Zhao, RC Fry, JJ Chen
British journal of haematology 143 (1), 129-137, 2008
Mandates: US National Institutes of Health
HRI coordinates translation necessary for protein homeostasis and mitochondrial function in erythropoiesis
S Zhang, A Macias-Garcia, JC Ulirsch, J Velazquez, VL Butty, SS Levine, ...
Elife 8, e46976, 2019
Mandates: US National Institutes of Health
miR-214 protects erythroid cells against oxidative stress by targeting ATF4 and EZH2
M Gao, Y Liu, Y Chen, C Yin, JJ Chen, S Liu
Free Radical Biology and Medicine 92, 39-49, 2016
Mandates: Chinese Academy of Sciences, National Natural Science Foundation of China
Expression of the translation initiation factors eIF-4E and eIF-2α is frequently increased in neoplastic cells of Hodgkin lymphoma
IB Rosenwald, L Koifman, L Savas, JJ Chen, BA Woda, ME Kadin
Human pathology 39 (6), 910-916, 2008
Mandates: US National Institutes of Health
Bitopertin, a selective oral GLYT1 inhibitor, improves anemia in a mouse model of β-thalassemia
A Matte, E Federti, M Winter, A Koerner, A Harmeier, N Mazer, T Tomka, ...
JCI insight 4 (22), 2019
Mandates: US National Institutes of Health
EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis
D Hidalgo, J Bejder, R Pop, K Gellatly, Y Hwang, S Maxwell Scalf, ...
Nature Communications 12 (1), 7334, 2021
Mandates: US National Institutes of Health
The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates
T Mukherjee, V Ramaglia, M Abdel-Nour, AA Bianchi, J Tsalikis, HN Chau, ...
Journal of Biological Chemistry 296, 2021
Mandates: Canadian Institutes of Health Research
Deficiency of heme-regulated eIF2α kinase decreases hepcidin expression and splenic iron in HFE−/− mice
S Liu, RNVS Suragani, A Han, W Zhao, NC Andrews, JJ Chen
Haematologica 93 (5), 753, 2008
Mandates: US National Institutes of Health
A novel mechanism for NF-κB-activation via IκB-aggregation: implications for hepatic mallory-denk-body induced inflammation
Y Liu, MJ Trnka, S Guan, D Kwon, DH Kim, JJ Chen, PA Greer, ...
Molecular & Cellular Proteomics 19 (12), 1968-1986, 2020
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
Translational control by heme-regulated elF2α kinase during erythropoiesis
JJ Chen, S Zhang
Current opinion in hematology 29 (3), 103-111, 2022
Mandates: US National Institutes of Health
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