The interaction between early life epilepsy and autistic-like behavioral consequences: a role for the mammalian target of rapamycin (mTOR) pathway DM Talos, H Sun, X Zhou, EC Fitzgerald, MC Jackson, PM Klein, VJ Lan, ... PloS one 7 (5), e35885, 2012 | 199 | 2012 |
Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex J Goto, DM Talos, P Klein, W Qin, YI Chekaluk, S Anderl, IA Malinowska, ... Proceedings of the National Academy of Sciences, 2011 | 190 | 2011 |
Development of later life spontaneous seizures in a rodent model of hypoxia‐induced neonatal seizures SN Rakhade, PM Klein, T Huynh, C Hilario‐Gomez, B Kosaras, ... Epilepsia, 2011 | 132 | 2011 |
New concerns for neurocognitive function during deep space exposures to chronic, low dose-rate, neutron radiation MM Acharya, JE Baulch, PM Klein, DB Al Anoud, LA Apodaca, EA Kramár, ... Eneuro 6 (4), 2019 | 106 | 2019 |
Alternating sources of perisomatic inhibition during behavior B Dudok, PM Klein, E Hwaun, BR Lee, Z Yao, O Fong, JC Bowler, ... Neuron 109 (6), 997-1012. e9, 2021 | 101 | 2021 |
AMPA receptor antagonist NBQX attenuates later‐life epileptic seizures and autistic‐like social deficits following neonatal seizures JJ Lippman‐Bell, SN Rakhade, PM Klein, M Obeid, MC Jackson, ... Epilepsia 54 (11), 1922-1932, 2013 | 77 | 2013 |
Glutamate Receptor 1 Phosphorylation at Serine 831 and 845 Modulates Seizure Susceptibility and Hippocampal Hyperexcitability after Early Life Seizures SN Rakhade, EF Fitzgerald, PM Klein, C Zhou, H Sun, RL Hunganir, ... The Journal of Neuroscience 32 (49), 17800-17812, 2012 | 70 | 2012 |
Recruitment and inhibitory action of hippocampal axo-axonic cells during behavior B Dudok, M Szoboszlay, A Paul, PM Klein, Z Liao, E Hwaun, GG Szabo, ... Neuron 109 (23), 3838-3850. e8, 2021 | 64 | 2021 |
Gene expression profiling of a hypoxic seizure model of epilepsy suggests a role for mTOR and Wnt signaling in epileptogenesis J Theilhaber, SN Rakhade, J Sudhalter, N Kothari, P Klein, J Pollard, ... PloS one 8 (9), e74428, 2013 | 50 | 2013 |
Mammalian target of rapamycin complex 1 activation negatively regulates Polo-like kinase 2-mediated homeostatic compensation following neonatal seizures H Sun, B Kosaras, PM Klein, FE Jensen Proceedings of the National Academy of Sciences 110 (13), 5199-5204, 2013 | 46 | 2013 |
Role of voltage‐gated calcium channels in the regulation of aldosterone production from zona glomerulosa cells of the adrenal cortex PQ Barrett, NA Guagliardo, PM Klein, C Hu, DT Breault, MP Beenhakker The Journal of physiology 594 (20), 5851-5860, 2016 | 45 | 2016 |
Chronic hyperoxia alters the early and late phases of the hypoxic ventilatory response in neonatal rats RW Bavis, KM Young, KJ Barry, MR Boller, E Kim, PM Klein, AR Ovrutsky, ... Journal of Applied Physiology 109 (3), 796-803, 2010 | 44 | 2010 |
Supramammillary regulation of locomotion and hippocampal activity JS Farrell, M Lovett-Barron, PM Klein, FT Sparks, T Gschwind, AL Ortiz, ... Science 374 (6574), 1492-1496, 2021 | 36 | 2021 |
Neonatal seizures alter NMDA glutamate receptor GluN2A and 3A subunit expression and function in hippocampal CA1 neurons C Zhou, H Sun, PM Klein, FE Jensen Frontiers in Cellular Neuroscience 9, 362, 2015 | 33 | 2015 |
Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes NA Guagliardo, PM Klein, CA Gancayco, A Lu, S Leng, RR Makarem, ... Nature Communications 11 (1), 1679, 2020 | 29 | 2020 |
Detrimental impacts of mixed-ion radiation on nervous system function PM Klein, VK Parihar, GG Szabo, M Zöldi, MC Angulo, BD Allen, AN Amin, ... Neurobiology of disease 151, 105252, 2021 | 26 | 2021 |
Lestaurtinib (CEP-701) attenuates “second hit” kainic acid-induced seizures following early life hypoxic seizures M Obeid, EC Rosenberg, PM Klein, FE Jensen Epilepsy research 108 (4), 806-810, 2014 | 25 | 2014 |
Tenuous inhibitory GABAergic signaling in the reticular thalamus PM Klein, AC Lu, ME Harper, HM McKown, JD Morgan, MP Beenhakker Journal of Neuroscience 38 (5), 1232-1248, 2018 | 23 | 2018 |
Neurological impairments in mice subjected to irradiation and chemotherapy D Dey, VK Parihar, GG Szabo, PM Klein, J Tran, J Moayyad, F Ahmed, ... Radiation research 193 (5), 407-424, 2020 | 22 | 2020 |
Toward understanding the diverse roles of perisomatic interneurons in epilepsy B Dudok, PM Klein, I Soltesz Epilepsy Currents 22 (1), 54-60, 2022 | 16 | 2022 |