A global view of hepatocellular carcinoma: trends, risk, prevention and management JD Yang, P Hainaut, GJ Gores, A Amadou, A Plymoth, LR Roberts Nature reviews Gastroenterology & hepatology 16 (10), 589-604, 2019 | 3419 | 2019 |
TP53 mutations in human cancers: origins, consequences, and clinical use M Olivier, M Hollstein, P Hainaut Cold Spring Harbor perspectives in biology 2 (1), a001008, 2010 | 2411 | 2010 |
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database A Petitjean, E Mathe, S Kato, C Ishioka, SV Tavtigian, P Hainaut, M Olivier Human mutation 28 (6), 622-629, 2007 | 2038 | 2007 |
The IARC TP53 database: new online mutation analysis and recommendations to users M Olivier, R Eeles, M Hollstein, MA Khan, CC Harris, P Hainaut Human mutation 19 (6), 607-614, 2002 | 1558 | 2002 |
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25 RJ Hung, JD McKay, V Gaborieau, P Boffetta, M Hashibe, D Zaridze, ... Nature 452 (7187), 633-637, 2008 | 1487 | 2008 |
Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers GP Pfeifer, MF Denissenko, M Olivier, N Tretyakova, SS Hecht, P Hainaut Oncogene 21 (48), 7435-7451, 2002 | 1397 | 2002 |
p53 and human cancer: the first ten thousand mutations P Hainaut, M Hollstein Advances in cancer research 77, 81-137, 1999 | 1363 | 1999 |
TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes A Petitjean, MIW Achatz, AL Borresen-Dale, P Hainaut, M Olivier Oncogene 26 (15), 2157-2165, 2007 | 1127 | 2007 |
The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer. M Olivier, A Langer√∏ d, P Carrieri, J Bergh, S Klaar, J Eyfjord, ... Clinical cancer research: an official journal of the American Association …, 2006 | 706 | 2006 |
Li-Fraumeni and related syndromes: correlation between tumor type, family structure, and TP53 genotype M Olivier, DE Goldgar, N Sodha, H Ohgaki, P Kleihues, P Hainaut, ... Cancer research 63 (20), 6643-6650, 2003 | 665 | 2003 |
PRIMA-1 reactivates mutant p53 by covalent binding to the core domain JMR Lambert, P Gorzov, DB Veprintsev, M Söderqvist, D Segerbäck, ... Cancer cell 15 (5), 376-388, 2009 | 655 | 2009 |
Circulating free DNA in plasma or serum as biomarker of carcinogenesis: practical aspects and biological significance E Gormally, E Caboux, P Vineis, P Hainaut Mutation Research/Reviews in Mutation Research 635 (2-3), 105-117, 2007 | 600 | 2007 |
IARC Database of p53 gene mutations in human tumors and cell lines: updated compilation, revised formats and new visualisation tools P Hainaut, T Hernandez, A Robinson, P Rodriguez-Tome, T Flores, ... Nucleic acids research 26 (1), 205-213, 1998 | 574 | 1998 |
Association between pre-diagnostic circulating vitamin D concentration and risk of colorectal cancer in European populations: a nested case-control study M Jenab, HB Bueno-de-Mesquita, P Ferrari, FJB van Duijnhoven, T Norat, ... Bmj 340, 2010 | 566 | 2010 |
Redox Modulation of p53 Conformation and Sequence-specific DNA Binding in Vitro P Hainaut, JO Milner Cancer research 53 (19), 4469-4473, 1993 | 541 | 1993 |
Patterns of p53 G→ T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke P Hainaut, GP Pfeifer Carcinogenesis 22 (3), 367-374, 2001 | 525 | 2001 |
Ectopic activation of germline and placental genes identifies aggressive metastasis-prone lung cancers S Rousseaux, A Debernardi, B Jacquiau, AL Vitte, A Vesin, ... Science translational medicine 5 (186), 186ra66-186ra66, 2013 | 487 | 2013 |
Environmental tobacco smoke and risk of respiratory cancer and chronic obstructive pulmonary disease in former smokers and never smokers in the EPIC prospective study P Vineis, L Airoldi, F Veglia, L Olgiati, R Pastorelli, H Autrup, A Dunning, ... Bmj 330 (7486), 277, 2005 | 446 | 2005 |
Computational approaches for predicting the biological effect of p53 missense mutations: a comparison of three sequence analysis based methods E Mathe, M Olivier, S Kato, C Ishioka, P Hainaut, SV Tavtigian Nucleic acids research 34 (5), 1317-1325, 2006 | 404 | 2006 |
Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects P Hainaut, T Soussi, B Shomer, M Hollstein, M Greenblatt, E Hovig, ... Nucleic acids research 25 (1), 151-157, 1997 | 398 | 1997 |