Rational modulation of conformational fluctuations in adenylate kinase reveals a local unfolding mechanism for allostery and functional adaptation in proteins TP Schrank, DW Bolen, VJ Hilser Proceedings of the National Academy of Sciences 106 (40), 16984-16989, 2009 | 180 | 2009 |
NRF2 activation in cancer: from DNA to protein EW Cloer, D Goldfarb, TP Schrank, BE Weissman, MB Major Cancer research 79 (5), 889-898, 2019 | 154 | 2019 |
Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell M Puray-Chavez, KM LaPak, TP Schrank, JL Elliott, DP Bhatt, ... Cell Reports 36 (2), 2021 | 136 | 2021 |
The role of protein conformational fluctuations in allostery, function, and evolution JO Wrabl, J Gu, T Liu, TP Schrank, ST Whitten, VJ Hilser Biophysical chemistry 159 (1), 129-141, 2011 | 131 | 2011 |
Case‐matching analysis of head and neck squamous cell carcinoma in racial and ethnic minorities in the United States—possible role for human papillomavirus in survival disparities TP Schrank, Y Han, H Weiss, VA Resto Head & neck 33 (1), 45-53, 2011 | 68 | 2011 |
Evolutionary conservation of the polyproline II conformation surrounding intrinsically disordered phosphorylation sites W Austin Elam, TP Schrank, AJ Campagnolo, VJ Hilser Protein Science 22 (4), 405-417, 2013 | 56 | 2013 |
Phosphorylation increases persistence length and end-to-end distance of a segment of tau protein AF Chin, D Toptygin, WA Elam, TP Schrank, VJ Hilser Biophysical journal 110 (2), 362-371, 2016 | 50 | 2016 |
Loss of SWI/SNF chromatin remodeling alters NRF2 signaling in non–small cell lung carcinoma S Song, V Nguyen, T Schrank, K Mulvaney, V Walter, D Wei, T Orvis, ... Molecular Cancer Research 18 (12), 1777-1788, 2020 | 32 | 2020 |
Temperature and urea have opposing impacts on polyproline II conformational bias WA Elam, TP Schrank, AJ Campagnolo, VJ Hilser Biochemistry 52 (5), 949-958, 2013 | 28 | 2013 |
Racial and ethnic disparities in salivary gland cancer survival JL Russell, NW Chen, SJ Ortiz, TP Schrank, YF Kuo, VA Resto JAMA Otolaryngology–Head & Neck Surgery 140 (6), 504-512, 2014 | 26 | 2014 |
Gain-of-function genetic screen of the kinome reveals BRSK2 as an inhibitor of the NRF2 transcription factor TY Tamir, BM Bowman, MJ Agajanian, D Goldfarb, TP Schrank, T Stohrer, ... Journal of cell science 133 (14), jcs241356, 2020 | 25 | 2020 |
Conformational Heterogeneity Within the LID Domain Mediates Substrate Binding to Escherichia coli Adenylate Kinase: Function Follows Fluctuations TP Schrank, JO Wrabl, VJ Hilser Dynamics in Enzyme Catalysis, 95-121, 2013 | 24 | 2013 |
Ketorolac and hematoma incidence in postmastectomy implant-based breast reconstruction Y Mikhaylov, B Weinstein, TP Schrank, JD Swartz, JP Ulm, MB Armstrong, ... Annals of Plastic Surgery 80 (5), 472-474, 2018 | 23 | 2018 |
A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue BM Bowman, SA Montgomery, TP Schrank, JM Simon, TS Ptacek, ... The Journal of pathology 252 (2), 125-137, 2020 | 20 | 2020 |
Strategies for the thermodynamic characterization of linked binding/local folding reactions within the native state: application to the LID domain of adenylate kinase from … TP Schrank, WA Elam, J Li, VJ Hilser Methods in enzymology 492, 253-282, 2011 | 19 | 2011 |
Thirty‐day readmission in patients undergoing head and neck microvascular reconstruction EM Graboyes, TP Schrank, ML Worley, SR Momin, TA Day, AT Huang Head & neck 40 (7), 1366-1374, 2018 | 18 | 2018 |
Direct comparison of HPV16 viral genomic integration, copy loss, and structural variants in oropharyngeal and uterine cervical cancers reveal distinct relationships to E2 … TP Schrank, S Kim, H Rehmani, A Kothari, D Wu, WG Yarbrough, ... Cancers 14 (18), 4488, 2022 | 13 | 2022 |
Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell. Cell Rep 36: 109364 M Puray-Chavez, KM LaPak, TP Schrank, JL Elliott, DP Bhatt, ... | 12 | 2021 |
Comprehensive viral genotyping reveals prognostic viral phylogenetic groups in HPV16-associated squamous cell carcinoma of the oropharynx TP Schrank, L Landess, WH Stepp, H Rehmani, WH Weir, N Lenze, A Lal, ... Molecular Cancer Research 20 (10), 1489-1501, 2022 | 11 | 2022 |
Correlation of alterations in the KEAP1/CUL3/NFE2L2 pathway with radiation failure in larynx squamous cell carcinoma S Sheth, DR Farquhar, TP Schrank, W Stepp, A Mazul, M Hayward, ... Laryngoscope investigative otolaryngology 6 (4), 699-707, 2021 | 11 | 2021 |