The effect of total tumor volume on the biologically effective dose to tumor and kidneys for 177Lu-labeled PSMA peptides NJ Begum, A Thieme, N Eberhardt, R Tauber, C D’Alessandria, AJ Beer, ... Journal of Nuclear Medicine 59 (6), 929-933, 2018 | 71 | 2018 |
The effect of ligand amount, affinity and internalization on PSMA-targeted imaging and therapy: A simulation study using a PBPK model NJ Begum, G Glatting, HJ Wester, M Eiber, AJ Beer, P Kletting Scientific reports 9 (1), 20041, 2019 | 50 | 2019 |
Important pharmacokinetic parameters for individualization of 177Lu‐PSMA therapy: A global sensitivity analysis for a physiologically‐based pharmacokinetic model D Hardiansyah, P Kletting, NJ Begum, M Eiber, AJ Beer, SA Pawiro, ... Medical Physics 48 (2), 556-568, 2021 | 19 | 2021 |
Treatment planning in PRRT based on simulated PET data and a PBPK model D Hardiansyah, W Guo, AA Attarwala, P Kletting, FM Mottaghy, G Glatting Nuklearmedizin-NuclearMedicine 56 (01), 23-30, 2017 | 15 | 2017 |
Sensitivity analysis of a physiologically based pharmacokinetic model used for treatment planning in peptide receptor radionuclide therapy D Hardiansyah, NJ Begum, P Kletting, FM Mottaghy, G Glatting Cancer Biotherapy and Radiopharmaceuticals 31 (6), 217-224, 2016 | 12 | 2016 |
An in silico study on the effect of the radionuclide half-life on PET/CT imaging with PSMA-targeting radioligands NJ Begum, G Glatting, M Eiber, AJ Beer, P Kletting Nuklearmedizin-NuclearMedicine 60 (01), 33-37, 2021 | 3 | 2021 |
Global Sensitivity Analysis of a Physiologically-Based Pharmacokinetic Model used for Treatment Planning in Lu-177-labelled PSMA Therapy D Hardiansyah, P Kletting, NJ Begum, A Beer, S Pawiro, G Glatting Journal of Nuclear Medicine 61 (supplement 1), 1405-1405, 2020 | 2 | 2020 |
Pb-212-labelled monoclonal antibodies: A PBPK model for treatment planning in Targeted Alpha-particle Therapy (TAT) N Zaid, N Begum, P Kletting, A Beer, G Glatting EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 46 (SUPPL 1), S57-S57, 2019 | 1 | 2019 |
Influence of affinity and total ligand amounts on pharmacokinetics and absorbed doses of PSMA-specific ligands: A simulation study N Begum, G Glatting, M Eiber, A Beer, P Kletting EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 46 (SUPPL 1 …, 2019 | 1 | 2019 |
The effect of the total tumour volume on the kidneys, salivary glands and tumour BEDs for Lu-177-labelled PSMA ligands NJ Begum, A Thieme, J Allmann, M Eiber, AJ Beer, G Glatting, P Kletting EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 44, S271-S271, 2017 | 1 | 2017 |
Optimization of imaging and therapy for a radioligand targeting the prostate-specific membrane antigen using a physiologically-based pharmacokinetic model NJ Begum Universität Ulm, 2022 | | 2022 |
Globale Sensitivitätsanalyse für ein PBPK-Modell zur Identifizierung der wichtigsten pharmakokinetischen Parameter für die Individualisierung der Lu-177-PSMA-Therapie D Hardiansyah, P Kletting, NJ Begum, M Eiber, AJ Beer, SA Pawiro, ... Nuklearmedizin-NuclearMedicine 60 (02), V40, 2021 | | 2021 |
Individualization of Lu-177-PSMA Therapy based on important physiologic parameters using global sensitivity analysis and a physiologically-based pharmacokinetic model G Glatting, P Kletting, NJ Begum, M Eiber, AJ Beer, SA Pawiro, ... EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 47 (SUPPL 1 …, 2020 | | 2020 |
Tumor Anti-Vascular Alpha Therapy with a 212Pb in vivo alpha generator: A mathematical model to improve treatment planning N Zaid, N Begum, P Kletting, A Beer, G Glatting Journal of Nuclear Medicine 61 (supplement 1), 528-528, 2020 | | 2020 |
Einfluss der physikalischen Halbwertszeit auf die PET/CT-Bildgebung mit PSMA-spezifischen Radioliganden: Eine Simulationsstudie NJ Begum, G Glatting, M Eiber, AJ Beer, P Kletting Nuklearmedizin-NuclearMedicine 59 (02), V4, 2020 | | 2020 |
A mathematical model to improve Tumour Anti-Vascular Alpha Therapy (TAVAT) with 212Pb-labelled monoclonal antibodies N Zaid, NJ Begum, P Kletting, AJ Beer, G Glatting Nuklearmedizin-NuclearMedicine 59 (02), P124, 2020 | | 2020 |
Combined effect of affinity and injected peptide amount on the pharmacokinetics of PSMA-specific peptide NJ Begum, G Glatting, A Allmann, J Allmann, M Eiber, A Beer, P Kletting Journal of Nuclear Medicine 60 (supplement 1), 11-11, 2019 | | 2019 |
Pharmakokinetik PSMA-spezifischer Liganden in Abhängigkeit von Affinität und Stoffmenge: Eine Simulationsstudie NJ Begum, A Thieme, N Eberhardt, R Tauber, M Eiber, AJ Beer, ... Nuklearmedizin-NuclearMedicine 58 (02), V11, 2019 | | 2019 |
Determination of the internalization rate of radiolabeled ligands by mathematical modeling G Winter, A Vogt, N Begum, C Solbach, A Beer, G Glatting, P Kletting Journal of Nuclear Medicine 59 (supplement 1), 1294-1294, 2018 | | 2018 |
Tumorvolumen und effektive Dosis der 177Lu-PSMA-Radioligan-dentherapie NJ Begum J Nucl Med 59, 929-933, 2018 | | 2018 |