Macrofilaricidal activity after doxycycline treatment of Wuchereria bancrofti: a double-blind, randomised placebo-controlled trial MJ Taylor, WH Makunde, HF McGarry, JD Turner, S Mand, A Hoerauf The Lancet 365 (9477), 2116-2121, 2005 | 361 | 2005 |
Th2 cytokines are associated with reduced worm burdens in a human intestinal helminth infection JD Turner, H Faulkner, J Kamgno, F Cormont, J Van Snick, KJ Else, ... The Journal of infectious diseases 188 (11), 1768-1775, 2003 | 247 | 2003 |
Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis JD Turner, RS Langley, KL Johnston, K Gentil, L Ford, B Wu, M Graham, ... Journal of Biological Chemistry 284 (33), 22364-22378, 2009 | 179 | 2009 |
Macrofilaricidal Activity after Doxycycline Only Treatment of Onchocerca volvulus in an Area of Loa loa Co-Endemicity: A Randomized Controlled Trial JD Turner, N Tendongfor, M Esum, KL Johnston, RS Langley, L Ford, ... PLoS neglected tropical diseases 4 (4), e660, 2010 | 170 | 2010 |
Allergen-specific IgE and IgG4 are markers of resistance and susceptibility in a human intestinal nematode infection JD Turner, H Faulkner, J Kamgno, MW Kennedy, J Behnke, M Boussinesq, ... Microbes and Infection 7 (7-8), 990-996, 2005 | 164 | 2005 |
Intensity of intestinal infection with multiple worm species is related to regulatory cytokine output and immune hyporesponsiveness JD Turner, JA Jackson, H Faulkner, J Behnke, KJ Else, J Kamgno, ... The Journal of infectious diseases 197 (8), 1204-1212, 2008 | 163 | 2008 |
T helper cell type 2 responsiveness predicts future susceptibility to gastrointestinal nematodes in humans JA Jackson, JD Turner, L Rentoul, H Faulkner, JM Behnke, M Hoyle, ... The Journal of infectious diseases 190 (10), 1804-1811, 2004 | 160 | 2004 |
Age-and infection intensity-dependent cytokine and antibody production in human trichuriasis: the importance of IgE H Faulkner, J Turner, J Kamgno, SD Pion, M Boussinesq, JE Bradley The Journal of infectious diseases 185 (5), 665-674, 2002 | 152 | 2002 |
A Randomized, Double-Blind Clinical Trial of a 3-Week Course of Doxycycline plus Albendazole and Ivermectin for the Treatment of Wuchereria bancrofti Infection JD Turner, S Mand, AY Debrah, J Muehlfeld, K Pfarr, HF McGarry, O Adjei, ... Clinical Infectious Diseases 42 (8), 1081-1089, 2006 | 142 | 2006 |
Granulocytes in helminth infection-who is calling the shots? B L Makepeace, C Martin, J D Turner, S Specht Current medicinal chemistry 19 (10), 1567-1586, 2012 | 120 | 2012 |
CD4+CD25+ Regulatory Cells Contribute to the Regulation of Colonic Th2 Granulomatous Pathology Caused by Schistosome Infection JD Turner, GR Jenkins, KG Hogg, SA Aynsley, RA Paveley, PC Cook, ... PLoS neglected tropical diseases 5 (8), e1269, 2011 | 108 | 2011 |
The Mannose Receptor (CD206) is an important pattern recognition receptor (PRR) in the detection of the infective stage of the helminth Schistosoma mansoni and modulates IFNγ … RA Paveley, SA Aynsley, JD Turner, CD Bourke, SJ Jenkins, PC Cook, ... International journal for parasitology 41 (13-14), 1335-1345, 2011 | 105 | 2011 |
Wolbachia endosymbiotic bacteria of Brugia malayi mediate macrophage tolerance to TLR-and CD40-specific stimuli in a MyD88/TLR2-dependent manner JD Turner, RS Langley, KL Johnston, G Egerton, S Wanji, MJ Taylor The Journal of Immunology 177 (2), 1240-1249, 2006 | 104 | 2006 |
Fluorescent imaging of antigen released by a skin-invading helminth reveals differential uptake and activation profiles by antigen presenting cells RA Paveley, SA Aynsley, PC Cook, JD Turner, AP Mountford PLoS Neglected Tropical Diseases 3 (10), e528, 2009 | 79 | 2009 |
Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis MJ Taylor, TW von Geldern, L Ford, MP Hübner, K Marsh, KL Johnston, ... Science translational medicine 11 (483), eaau2086, 2019 | 76 | 2019 |
Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and … G Aljayyoussi, HE Tyrer, L Ford, H Sjoberg, N Pionnier, D Waterhouse, ... Scientific reports 7 (1), 210, 2017 | 75 | 2017 |
Cytokine response profiles predict species-specific infection patterns in human GI nematodes JA Jackson, JD Turner, L Rentoul, H Faulkner, JM Behnke, M Hoyle, ... International Journal for Parasitology 34 (11), 1237-1244, 2004 | 71 | 2004 |
Wolbachia-Induced Neutrophil Activation in a Mouse Model of Ocular Onchocerciasis (River Blindness) I Gillette-Ferguson, AG Hise, HF McGarry, J Turner, A Esposito, Y Sun, ... Infection and immunity 72 (10), 5687-5692, 2004 | 70 | 2004 |
AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis WD Hong, F Benayoud, GL Nixon, L Ford, KL Johnston, RH Clare, ... Proceedings of the National Academy of Sciences 116 (4), 1414-1419, 2019 | 69 | 2019 |
A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis A Halliday, AF Guimaraes, HE Tyrer, HM Metuge, CNW Patrick, ... Parasites & vectors 7, 1-14, 2014 | 68 | 2014 |