Wnt ligands secreted by subepithelial mesenchymal cells are essential for the survival of intestinal stem cells and gut homeostasis T Valenta, B Degirmenci, AE Moor, P Herr, D Zimmerli, MB Moor, ... Cell reports 15 (5), 911-918, 2016 | 281 | 2016 |
TCF/LEF dependent and independent transcriptional regulation of Wnt/β‐catenin target genes N Doumpas, F Lampart, MD Robinson, A Lentini, CE Nestor, C Cantù, ... The EMBO Journal 38 (2), e98873, 2019 | 186 | 2019 |
Persistent Wnt/β‐Catenin Signaling Determines Dorsalization of the Postnatal Subventricular Zone and Neural Stem Cell Specification into Oligodendrocytes and … K Azim, B Fischer, A Hurtado‐Chong, K Draganova, C Cantù, M Zemke, ... Stem cells 32 (5), 1301-1312, 2014 | 102 | 2014 |
Sox6 enhances erythroid differentiation in human erythroid progenitors C Cantù, R Ierardi, I Alborelli, C Fugazza, L Cassinelli, S Piconese, ... Blood, The Journal of the American Society of Hematology 117 (13), 3669-3679, 2011 | 82 | 2011 |
The WNT/β‐catenin dependent transcription: A tissue‐specific business S Söderholm, C Cantù Wiley Interdisciplinary Reviews: Systems Biology and Medicine, e1511, 2020 | 73 | 2020 |
Pharmacological interventions in the Wnt pathway: inhibition of Wnt secretion versus disrupting the protein–protein interfaces of nuclear factors D Zimmerli, G Hausmann, C Cantù, K Basler British Journal of Pharmacology 174 (24), 4600-4610, 2017 | 71 | 2017 |
Wnt/β-catenin signaling regulates sequential fate decisions of murine cortical precursor cells K Draganova, M Zemke, L Zurkirchen, T Valenta, C Cantù, M Okoniewski, ... Stem cells 33 (1), 170-182, 2015 | 71 | 2015 |
BCL9/9L-β-catenin signaling is associated with poor outcome in colorectal cancer AE Moor, P Anderle, C Cantù, P Rodriguez, N Wiedemann, F Baruthio, ... EBioMedicine 2 (12), 1932-1943, 2015 | 67 | 2015 |
A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation C Cantù, P Pagella, TD Shajiei, D Zimmerli, T Valenta, G Hausmann, ... Science signaling 10 (465), eaah4598, 2017 | 66 | 2017 |
Pharmacogenomic identification of small molecules for lineage specific manipulation of subventricular zone germinal activity K Azim, D Angonin, G Marcy, F Pieropan, A Rivera, V Donega, C Cantù, ... PLoS biology 15 (3), e2000698, 2017 | 60 | 2017 |
Yin Yang 1 orchestrates a metabolic program required for both neural crest development and melanoma formation S Varum, A Baggiolini, L Zurkirchen, ZK Atak, C Cantù, E Marzorati, ... Cell stem cell 24 (4), 637-653. e9, 2019 | 54 | 2019 |
Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling C Cantù, A Felker, D Zimmerli, KD Prummel, EM Cabello, E Chiavacci, ... Genes & development 32 (21-22), 1443-1458, 2018 | 53 | 2018 |
Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development C Cantù, D Zimmerli, G Hausmann, T Valenta, A Moor, M Aguet, K Basler Genes & development 28 (17), 1879-1884, 2014 | 51 | 2014 |
The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription C Cantù, T Valenta, G Hausmann, N Vilain, M Aguet, K Basler Development 140 (11), 2377-2386, 2013 | 48 | 2013 |
TBX3 acts as tissue-specific component of the Wnt/β-catenin transcriptional complex D Zimmerli, C Borrelli, A Jauregi-Miguel, S Söderholm, S Brütsch, ... Elife 9, e58123, 2020 | 46* | 2020 |
Sox2 controls neural stem cell self-renewal through a Fos-centered gene regulatory network M Pagin, S Giubbolini, C Barone, G Sambruni, Y Zhu, S Ottolenghi, ... bioRxiv, 2021 | 41 | 2021 |
Reactivation of a developmental Bmp2 signaling center is required for therapeutic control of the murine periosteal niche VS Salazar, LP Capelo, C Cantù, D Zimmerli, N Gosalia, S Pregizer, ... eLife 8, e42386, 2019 | 35 | 2019 |
Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner L Zurkirchen, S Varum, S Giger, A Klug, J Häusel, R Bossart, M Zemke, ... Nature communications 10 (1), 2192, 2019 | 34 | 2019 |
WNT ligands control initiation and progression of human papillomavirus-driven squamous cell carcinoma D Zimmerli, V Cecconi, T Valenta, G Hausmann, C Cantù, G Restivo, ... Oncogene 37 (27), 3753-3762, 2018 | 28 | 2018 |
Pharmacophore-guided discovery of CDC25 inhibitors causing cell cycle arrest and tumor regression Z Kabakci, S Käppeli, C Cantù, LD Jensen, C König, J Toggweiler, ... Scientific reports 9 (1), 1335, 2019 | 27 | 2019 |