Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors P Huang, Z He, S Ji, H Sun, D Xiang, C Liu, Y Hu, X Wang, L Hui nature 475 (7356), 386-389, 2011 | 1017 | 2011 |
Direct reprogramming of human fibroblasts to functional and expandable hepatocytes P Huang, L Zhang, Y Gao, Z He, D Yao, Z Wu, J Cen, X Chen, C Liu, Y Hu, ... Cell stem cell 14 (3), 370-384, 2014 | 596 | 2014 |
p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway L Hui, L Bakiri, A Mairhorfer, N Schweifer, C Haslinger, L Kenner, ... Nature genetics 39 (6), 741-749, 2007 | 465 | 2007 |
Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation L Hui, K Zatloukal, H Scheuch, E Stepniak, EF Wagner The Journal of clinical investigation 118 (12), 3943-3953, 2008 | 401 | 2008 |
Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin L Min, Y Ji, L Bakiri, Z Qiu, J Cen, X Chen, L Chen, H Scheuch, H Zheng, ... Nature cell biology 14 (11), 1203-1211, 2012 | 277 | 2012 |
MAPK signaling in inflammation-associated cancer development P Huang, J Han, L Hui Protein & cell 1, 218-226, 2010 | 277 | 2010 |
Chronic liver injury induces conversion of biliary epithelial cells into hepatocytes X Deng, X Zhang, W Li, RX Feng, LU Li, GR Yi, XN Zhang, C Yin, HY Yu, ... Cell stem cell 23 (1), 114-122. e3, 2018 | 257 | 2018 |
p38α: a suppressor of cell proliferation and tumorigenesis L Hui, L Bakiri, E Stepniak, EF Wagner Cell cycle 6 (20), 2429-2433, 2007 | 240 | 2007 |
Mitogen-activated protein kinases in hepatocellular carcinoma development L Min, B He, L Hui Seminars in cancer biology 21 (1), 10-20, 2011 | 223 | 2011 |
In vitro expansion of primary human hepatocytes with efficient liver repopulation capacity K Zhang, L Zhang, W Liu, X Ma, J Cen, Z Sun, C Wang, S Feng, Z Zhang, ... Cell stem cell 23 (6), 806-819. e4, 2018 | 208 | 2018 |
A pharmacogenomic landscape in human liver cancers Z Qiu, H Li, Z Zhang, Z Zhu, S He, X Wang, P Wang, J Qin, L Zhuang, ... Cancer Cell 36 (2), 179-193. e11, 2019 | 165 | 2019 |
Improved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytes XL Shi, Y Gao, Y Yan, H Ma, L Sun, P Huang, X Ni, L Zhang, X Zhao, ... Cell research 26 (2), 206-216, 2016 | 146 | 2016 |
Modelling liver cancer initiation with organoids derived from directly reprogrammed human hepatocytes L Sun, Y Wang, J Cen, X Ma, L Cui, Z Qiu, Z Zhang, H Li, RZ Yang, ... Nature cell biology 21 (8), 1015-1026, 2019 | 131 | 2019 |
Cell plasticity in liver regeneration W Li, L Li, L Hui Trends in cell biology 30 (4), 329-338, 2020 | 124 | 2020 |
A homeostatic Arid1a-dependent permissive chromatin state licenses hepatocyte responsiveness to liver-injury-associated YAP signaling W Li, L Yang, Q He, C Hu, L Zhu, X Ma, X Ma, S Bao, L Li, Y Chen, ... Cell Stem Cell 25 (1), 54-68. e5, 2019 | 105 | 2019 |
miR-27b synergizes with anticancer drugs via p53 activation and CYP1B1 suppression W Mu, C Hu, H Zhang, Z Qu, J Cen, Z Qiu, C Li, H Ren, Y Li, X He, X Shi, ... Cell research 25 (4), 477-495, 2015 | 97 | 2015 |
Hepatocellular carcinoma cell lines retain the genomic and transcriptomic landscapes of primary human cancers Z Qiu, K Zou, L Zhuang, J Qin, H Li, C Li, Z Zhang, X Chen, J Cen, Z Meng, ... Scientific Reports 6 (1), 27411, 2016 | 67 | 2016 |
Arid1a regulates response to anti-angiogenic therapy in advanced hepatocellular carcinoma C Hu, W Li, F Tian, K Jiang, X Liu, J Cen, Q He, Z Qiu, Y Kienast, Z Wang, ... Journal of hepatology 68 (3), 465-475, 2018 | 58 | 2018 |
Distinct gene expression and epigenetic signatures in hepatocyte-like cells produced by different strategies from the same donor Y Gao, X Zhang, L Zhang, J Cen, X Ni, X Liao, C Yang, Y Li, X Chen, ... Stem Cell Reports 9 (6), 1813-1824, 2017 | 48 | 2017 |
Progress in human liver organoids L Sun, L Hui Journal of Molecular Cell Biology 12 (8), 607-617, 2020 | 47 | 2020 |