Prions, prionoids and protein misfolding disorders C Scheckel, A Aguzzi Nature Reviews Genetics 19 (7), 405-418, 2018 | 306 | 2018 |
Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk J Zhou, CY Park, CL Theesfeld, AK Wong, Y Yuan, C Scheckel, JJ Fak, ... Nature genetics 51 (6), 973-980, 2019 | 284 | 2019 |
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP β-CTFs, not Aβ D Kwart, A Gregg, C Scheckel, EA Murphy, D Paquet, M Duffield, J Fak, ... Neuron 104 (2), 256-270. e5, 2019 | 263 | 2019 |
Phosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment SL Clement, C Scheckel, G Stoecklin, J Lykke-Andersen Molecular and cellular biology 31 (2), 256-266, 2011 | 238 | 2011 |
Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain C Scheckel, E Drapeau, MA Frias, CY Park, J Fak, I Zucker-Scharff, Y Kou, ... Elife 5, e10421, 2016 | 150 | 2016 |
Genome-Wide Analysis of GLD-1–Mediated mRNA Regulation Suggests a Role in mRNA Storage C Scheckel, D Gaidatzis, JE Wright, R Ciosk PLoS genetics 8 (5), e1002742, 2012 | 56 | 2012 |
Genome-wide transcriptomics identifies an early preclinical signature of prion infection S Sorce, M Nuvolone, G Russo, A Chincisan, D Heinzer, M Avar, ... PLoS pathogens 16 (6), e1008653, 2020 | 51 | 2020 |
Functional characterization of C. elegans Y-box-binding proteins reveals tissue-specific functions and a critical role in the formation of polysomes A Arnold, MM Rahman, MC Lee, S Muehlhaeusser, I Katic, D Gaidatzis, ... Nucleic acids research 42 (21), 13353-13369, 2014 | 49 | 2014 |
Ribosomal profiling during prion disease uncovers progressive translational derangement in glia but not in neurons C Scheckel, M Imeri, P Schwarz, A Aguzzi Elife 9, e62911, 2020 | 43 | 2020 |
LARP-1 promotes oogenesis by repressing fem-3 in the C. elegans germline E Zanin, A Pacquelet, C Scheckel, R Ciosk, M Gotta Journal of cell science 123 (16), 2717-2724, 2010 | 23 | 2010 |
Microexons—tiny but mighty C Scheckel, RB Darnell The EMBO journal 34 (3), 273-274, 2015 | 22 | 2015 |
Genome‐wide identification of microRNAs regulating the human prion protein D Pease, C Scheckel, E Schaper, V Eckhardt, M Emmenegger, I Xenarios, ... Brain Pathology 29 (2), 232-244, 2019 | 19 | 2019 |
Soluble dimeric prion protein ligand activates Adgrg6 receptor but does not rescue early signs of demyelination in PrP-deficient mice A Henzi, A Senatore, AKK Lakkaraju, C Scheckel, J Mühle, R Reimann, ... PLoS One 15 (11), e0242137, 2020 | 12 | 2020 |
Whole-genome deep learning analysis reveals causal role of noncoding mutations in autism J Zhou, CY Park, CL Theesfeld, Y Yuan, K Sawicka, JC Darnell, ... BioRxiv, 319681, 2018 | 9 | 2018 |
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab D Kwart, A Gregg, C Scheckel, E Murphy, D Paquet, M Duffield, J Fak, ... Neuron 104, 1-15, 2019 | 2 | 2019 |
Skeletal-Muscle Glutamine Synthase is Upregulated in Preclinical Prion Diseases D Caredio, M Koderman, K Frontzek, S Sorce, M Nuvolone, J Bremer, ... bioRxiv, N/A, 2023 | 1 | 2023 |
Dimeric prion protein ligand activates Adgrg6 but does not rescue myelinopathy of PrP-deficient mice A Henzi, A Senatore, AKK Lakkaraju, C Scheckel, J Mühle, R Reimann, ... bioRxiv, 2020.07. 07.191452, 2020 | 1 | 2020 |
Prion diseases disrupt glutamate/glutamine metabolism in skeletal muscle D Caredio, M Koderman, KJ Frontzek, S Sorce, M Nuvolone, J Bremer, ... PLoS pathogens 20 (9), e1012552, 2024 | | 2024 |
T helper 1 cell differentiation and activation, a multiomics approach J Koch, P Westermann, A Ruggia, C Beha, M Imeri, S Schmelzer, ... SWISS MEDICAL WEEKLY 153, 2S-3S, 2023 | | 2023 |
Prions induce minor genome-wide translational changes in neurons compared to glia C Scheckel, M Imeri, P Schwarz, A Aguzzi bioRxiv, 2020.06. 26.172841, 2020 | | 2020 |