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Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes P Mali, BK Chou, J Yen, Z Ye, J Zou, S Dowey, RA Brodsky, JE Ohm, ... Stem cells 28 (4), 713-720, 2010 | 578 | 2010 |
Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures BK Chou, P Mali, X Huang, Z Ye, SN Dowey, L Resar, C Zou, YA Zhang, ... Cell research 21 (3), 518-529, 2011 | 536 | 2011 |
Effectiveness of exome and genome sequencing guided by acuity of illness for diagnosis of neurodevelopmental disorders SE Soden, CJ Saunders, LK Willig, EG Farrow, LD Smith, JE Petrikin, ... Science translational medicine 6 (265), 265ra168-265ra168, 2014 | 531 | 2014 |
Human adult marrow cells support prolonged expansion of human embryonic stem cells in culture L Cheng, H Hammond, Z Ye, X Zhan, G Dravid Stem cells 21 (2), 131-142, 2003 | 502 | 2003 |
Defining the role of Wnt/β‐catenin signaling in the survival, proliferation, and self‐renewal of human embryonic stem cells G Dravid, Z Ye, H Hammond, G Chen, A Pyle, P Donovan, X Yu, L Cheng Stem cells 23 (10), 1489-1501, 2005 | 475 | 2005 |
Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders Z Ye, H Zhan, P Mali, S Dowey, DM Williams, YY Jang, CV Dang, ... Blood, The Journal of the American Society of Hematology 114 (27), 5473-5480, 2009 | 473 | 2009 |
Whole-genome sequencing analysis reveals high specificity of CRISPR/Cas9 and TALEN-based genome editing in human iPSCs C Smith, A Gore, W Yan, L Abalde-Atristain, Z Li, C He, Y Wang, ... Cell stem cell 15 (1), 12-13, 2014 | 435 | 2014 |
Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts P Mali, Z Ye, HH Hommond, X Yu, J Lin, G Chen, J Zou, L Cheng Stem cells 26 (8), 1998-2005, 2008 | 366 | 2008 |
In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cells NS Hwang, S Varghese, HJ Lee, Z Zhang, Z Ye, J Bae, L Cheng, ... Proceedings of the National Academy of Sciences 105 (52), 20641-20646, 2008 | 357 | 2008 |
Generation of endoderm‐derived human induced pluripotent stem cells from primary hepatocytes H Liu, Z Ye, Y Kim, S Sharkis, YY Jang Hepatology 51 (5), 1810-1819, 2010 | 309 | 2010 |
Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression L Cheng, NF Hansen, L Zhao, Y Du, C Zou, FX Donovan, BK Chou, ... Cell stem cell 10 (3), 337-344, 2012 | 296 | 2012 |
Efficient drug screening and gene correction for treating liver disease using patient‐specific stem cells SM Choi, Y Kim, JS Shim, JT Park, RH Wang, SD Leach, JO Liu, C Deng, ... Hepatology 57 (6), 2458-2468, 2013 | 274 | 2013 |
Production of gene-corrected adult beta globin protein in human erythrocytes differentiated from patient iPSCs after genome editing of the sickle point mutation X Huang, Y Wang, W Yan, C Smith, Z Ye, J Wang, Y Gao, L Mendelsohn, ... Stem cells 33 (5), 1470-1479, 2015 | 242 | 2015 |
Efficient and allele-specific genome editing of disease loci in human iPSCs C Smith, L Abalde-Atristain, C He, BR Brodsky, EM Braunstein, ... Molecular Therapy 23 (3), 570-577, 2015 | 240 | 2015 |
Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21-to 23.5-year cryopreserved cord blood HE Broxmeyer, MR Lee, G Hangoc, S Cooper, N Prasain, YJ Kim, ... Blood, The Journal of the American Society of Hematology 117 (18), 4773-4777, 2011 | 209 | 2011 |
Functional antigen-presenting leucocytes derived from human embryonic stem cells in vitro X Zhan, G Dravid, Z Ye, H Hammond, M Shamblott, J Gearhart, L Cheng The Lancet 364 (9429), 163-171, 2004 | 204 | 2004 |
Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells X Yu, X Zhan, J D'costa, VM Tanavde, Z Ye, T Peng, MT Malehorn, ... Molecular Therapy 7 (6), 827-838, 2003 | 200 | 2003 |
Generation of integration-free human induced pluripotent stem cells from postnatal blood mononuclear cells by plasmid vector expression SN Dowey, X Huang, BK Chou, Z Ye, L Cheng Nature protocols 7 (11), 2013-2021, 2012 | 195 | 2012 |
The phenotype of a germline mutation in PIGA: the gene somatically mutated in paroxysmal nocturnal hemoglobinuria JJ Johnston, AL Gropman, JC Sapp, JK Teer, JM Martin, CF Liu, X Yuan, ... The American Journal of Human Genetics 90 (2), 295-300, 2012 | 179 | 2012 |