Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines DS Wilson, G Dalmasso, L Wang, SV Sitaraman, D Merlin, N Murthy Nature materials 9 (11), 923-928, 2010 | 730 | 2010 |
Edible ginger-derived nanoparticles: A novel therapeutic approach for the prevention and treatment of inflammatory bowel disease and colitis-associated cancer M Zhang, E Viennois, M Prasad, Y Zhang, L Wang, Z Zhang, MK Han, ... Biomaterials 101, 321-340, 2016 | 694 | 2016 |
Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells NK Saxena, D Sharma, X Ding, S Lin, F Marra, D Merlin, FA Anania Cancer research 67 (6), 2497-2507, 2007 | 588 | 2007 |
Temporal and spatial analysis of clinical and molecular parameters in dextran sodium sulfate induced colitis Y Yan, V Kolachala, G Dalmasso, H Nguyen, H Laroui, SV Sitaraman, ... PloS one 4 (6), e6073, 2009 | 507 | 2009 |
Dextran sodium sulfate (DSS) induces colitis in mice by forming nano-lipocomplexes with medium-chain-length fatty acids in the colon H Laroui, SA Ingersoll, HC Liu, MT Baker, S Ayyadurai, MA Charania, ... PloS one 7 (3), e32084, 2012 | 422 | 2012 |
Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP FE Castaneda, B Walia, M Vijay–Kumar, NR Patel, S Roser, VL Kolachala, ... Gastroenterology 129 (6), 1991-2008, 2005 | 314 | 2005 |
Edible ginger-derived nano-lipids loaded with doxorubicin as a novel drug-delivery approach for colon cancer therapy M Zhang, B Xiao, H Wang, MK Han, Z Zhang, E Viennois, C Xu, D Merlin Molecular Therapy 24 (10), 1783-1796, 2016 | 306 | 2016 |
IL-6 induces NF-κB activation in the intestinal epithelia L Wang, B Walia, J Evans, AT Gewirtz, D Merlin, SV Sitaraman The Journal of Immunology 171 (6), 3194-3201, 2003 | 295 | 2003 |
hPepT1 transports muramyl dipeptide, activating NF-κB and stimulating IL-8 secretion in human colonic Caco2/bbe cells SR Vavricka, MW Musch, JE Chang, Y Nakagawa, K Phanvijhitsiri, ... Gastroenterology 127 (5), 1401-1409, 2004 | 287 | 2004 |
PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine M Buyse, F Berlioz, S Guilmeau, A Tsocas, T Voisin, G Péranzi, D Merlin, ... The Journal of clinical investigation 108 (10), 1483-1494, 2001 | 280 | 2001 |
Drug-loaded nanoparticles targeted to the colon with polysaccharide hydrogel reduce colitis in a mouse model H Laroui, G Dalmasso, HTT Nguyen, Y Yan, SV Sitaraman, D Merlin Gastroenterology 138 (3), 843-853. e2, 2010 | 276 | 2010 |
Salmonella typhimurium induces epithelial IL-8 expression via Ca2+-mediated activation of the NF-κB pathway AT Gewirtz, AS Rao, PO Simon, D Merlin, D Carnes, JL Madara, AS Neish The Journal of clinical investigation 105 (1), 79-92, 2000 | 259 | 2000 |
Plant derived edible nanoparticles as a new therapeutic approach against diseases M Zhang, E Viennois, C Xu, D Merlin Tissue barriers 4 (2), e1134415, 2016 | 258 | 2016 |
Dietary emulsifier–induced low-grade inflammation promotes colon carcinogenesis E Viennois, D Merlin, AT Gewirtz, B Chassaing Cancer research 77 (1), 27-40, 2017 | 241 | 2017 |
Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth … NK Saxena, LT Taliaferro-Smith, BB Knight, D Merlin, FA Anania, ... Cancer research 68 (23), 9712-9722, 2008 | 234 | 2008 |
Oral administration of ginger-derived nanolipids loaded with siRNA as a novel approach for efficient siRNA drug delivery to treat ulcerative colitis M Zhang, X Wang, MK Han, JF Collins, D Merlin Nanomedicine 12 (16), 1927-1943, 2017 | 230 | 2017 |
Neutrophil-epithelial crosstalk at the intestinal lumenal surface mediated by reciprocal secretion of adenosine and IL-6 SV Sitaraman, D Merlin, L Wang, M Wong, AT Gewirtz, M Si-Tahar, ... The Journal of clinical investigation 107 (7), 861-869, 2001 | 222 | 2001 |
Colonic epithelial hPepT1 expression occurs in inflammatory bowel disease: transport of bacterial peptides influences expression of MHC class 1 molecules D Merlin, M Si-Tahar, SV Sitaraman, K Eastburn, I Williams, X Liu, ... Gastroenterology 120 (7), 1666-1679, 2001 | 221 | 2001 |
Microbiota modulate host gene expression via microRNAs G Dalmasso, HTT Nguyen, Y Yan, H Laroui, MA Charania, S Ayyadurai, ... PloS one 6 (4), e19293, 2011 | 208 | 2011 |
The role of CD47 in neutrophil transmigration: increased rate of migration correlates with increased cell surface expression of CD47 Y Liu, D Merlin, SL Burst, M Pochet, JL Madara, CA Parkos Journal of Biological Chemistry 276 (43), 40156-40166, 2001 | 208 | 2001 |