| Biofilm formation mechanisms and targets for developing antibiofilm agents N Rabin, Y Zheng, C Opoku-Temeng, Y Du, E Bonsu, HO Sintim Future medicinal chemistry 7 (4), 493-512, 2015 | 822 | 2015 |
| Isothermal amplified detection of DNA and RNA L Yan, J Zhou, Y Zheng, AS Gamson, BT Roembke, S Nakayama, ... Molecular BioSystems 10 (5), 970-1003, 2014 | 482 | 2014 |
| Nucleotide, c-di-GMP, c-di-AMP, cGMP, cAMP,(p) ppGpp signaling in bacteria and implications in pathogenesis D Kalia, G Merey, S Nakayama, Y Zheng, J Zhou, Y Luo, M Guo, ... Chemical Society Reviews 42 (1), 305-341, 2013 | 431 | 2013 |
| Agents that inhibit bacterial biofilm formation N Rabin, Y Zheng, C Opoku-Temeng, Y Du, E Bonsu, HO Sintim Future medicinal chemistry 7 (5), 647-671, 2015 | 319 | 2015 |
| Differential radial capillary action of ligand assay for high-throughput detection of protein-metabolite interactions KG Roelofs, J Wang, HO Sintim, VT Lee Proceedings of the National Academy of Sciences 108 (37), 15528-15533, 2011 | 238 | 2011 |
| STING ligand c-di-GMP improves cancer vaccination against metastatic breast cancer D Chandra, W Quispe-Tintaya, A Jahangir, D Asafu-Adjei, I Ramos, ... Cancer immunology research 2 (9), 901-910, 2014 | 236 | 2014 |
| Colorimetric split G-quadruplex probes for nucleic acid sensing: improving reconstituted DNAzyme’s catalytic efficiency via probe remodeling S Nakayama, HO Sintim Journal of the American Chemical Society 131 (29), 10320-10333, 2009 | 210 | 2009 |
| Paradigm shift in discovering next-generation anti-infective agents: targeting quorum sensing, c-di-GMP signaling and biofilm formation in bacteria with small molecules HO Sintim, JAI Smith, J Wang, S Nakayama, L Yan Future medicinal chemistry 2 (6), 1005-1035, 2010 | 185 | 2010 |
| Unraveling curcumin degradation: autoxidation proceeds through spiroepoxide and vinylether intermediates en route to the main bicyclopentadione ON Gordon, PB Luis, HO Sintim, C Schneider Journal of Biological Chemistry 290 (8), 4817-4828, 2015 | 173 | 2015 |
| Oligoribonuclease is the primary degradative enzyme for pGpG in Pseudomonas aeruginosa that is required for cyclic-di-GMP turnover MW Orr, GP Donaldson, GB Severin, J Wang, HO Sintim, CM Waters, ... Proceedings of the National Academy of Sciences 112 (36), E5048-E5057, 2015 | 160 | 2015 |
| AI-2 analogs and antibiotics: a synergistic approach to reduce bacterial biofilms V Roy, MT Meyer, JAI Smith, S Gamby, HO Sintim, R Ghodssi, WE Bentley Applied microbiology and biotechnology 97, 2627-2638, 2013 | 127 | 2013 |
| Fluorescence, phosphorescence, and chemiluminescence N Siraj, B El-Zahab, S Hamdan, TE Karam, LH Haber, M Li, SO Fakayode, ... Analytical chemistry 88 (1), 170-202, 2016 | 117 | 2016 |
| A Noncarbohydrate Based Approach to Polyhydroxylated Pyrrolidizines: Total Syntheses of the Natural Products Hyacinthacine A1 and 1-Epiaustraline TJ Donohoe, HO Sintim, J Hollinshead The Journal of Organic Chemistry 70 (18), 7297-7304, 2005 | 105 | 2005 |
| Cyclic dinucleotide (c-di-GMP, c-di-AMP, and cGAMP) signalings have come of age to be inhibited by small molecules C Opoku-Temeng, J Zhou, Y Zheng, J Su, HO Sintim Chemical Communications 52 (60), 9327-9342, 2016 | 103 | 2016 |
| Inhibition of innate immune cytosolic surveillance by an M. tuberculosis phosphodiesterase RJ Dey, B Dey, Y Zheng, LS Cheung, J Zhou, D Sayre, P Kumar, H Guo, ... Nature chemical biology 13 (2), 210-217, 2017 | 96 | 2017 |
| Junction probes− sequence specific detection of nucleic acids via template enhanced hybridization processes S Nakayama, L Yan, HO Sintim Journal of the American Chemical Society 130 (38), 12560-12561, 2008 | 96 | 2008 |
| ENPP1, an old enzyme with new functions, and small molecule inhibitors—a STING in the tale of ENPP1 KI Onyedibe, M Wang, HO Sintim Molecules 24 (22), 4192, 2019 | 95 | 2019 |
| Suramin potently inhibits cGAMP synthase, cGAS, in THP1 cells to modulate IFN-β levels M Wang, MA Sooreshjani, C Mikek, C Opoku-Temeng, HO Sintim Future Medicinal Chemistry 10 (11), 1301-1317, 2018 | 95 | 2018 |
| Evidence of magnetic isotope effects during thermochemical sulfate reduction H Oduro, B Harms, HO Sintim, AJ Kaufman, G Cody, J Farquhar Proceedings of the National Academy of Sciences 108 (43), 17635-17638, 2011 | 93 | 2011 |
| Thiazole orange-induced c-di-GMP quadruplex formation facilitates a simple fluorescent detection of this ubiquitous biofilm regulating molecule S Nakayama, I Kelsey, J Wang, K Roelofs, B Stefane, Y Luo, VT Lee, ... Journal of the American Chemical Society 133 (13), 4856-4864, 2011 | 93 | 2011 |
Jie ZhouPurdue UniversityVerified email at purdue.edu
