Articles with public access mandates - Herman O. SintimLearn more
Not available anywhere: 12
Inhibition of innate immune cytosolic surveillance by an M. tuberculosis phosphodiesterase
RJ Dey, B Dey, Y Zheng, LS Cheung, J Zhou, D Sayre, P Kumar, H Guo, ...
Nature chemical biology 13 (2), 210-217, 2017
Mandates: US National Science Foundation, US National Institutes of Health, Howard …
Targeting c-di-GMP signaling, biofilm formation, and bacterial motility with small molecules
C Opoku-Temeng, HO Sintim
c-di-GMP Signaling: Methods and Protocols, 419-430, 2017
Mandates: US National Science Foundation
Differential binding of 2′-biotinylated analogs of c-di-GMP with c-di-GMP riboswitches and binding proteins
Y Luo, J Zhou, SK Watt, VT Lee, TK Dayie, HO Sintim
Molecular BioSystems 8 (3), 772-778, 2012
Mandates: US National Institutes of Health
Potently inhibiting cancer cell migration with novel 3H-pyrazolo [4, 3-f] quinoline boronic acid ROCK inhibitors
N Dayal, CG Mikek, D Hernandez, GA Naclerio, EFY Chu, ...
European journal of medicinal chemistry 180, 449-456, 2019
Mandates: US National Institutes of Health
Use of high-throughput tools for telescoped continuous flow synthesis of an alkynylnaphthyridine anticancer agent, HSN608
SA Biyani, Q Qi, J Wu, Y Moriuchi, EA Larocque, HO Sintim, ...
Organic Process Research & Development 24 (10), 2240-2251, 2020
Mandates: US Department of Defense
Identification of nicotinamide aminonaphthyridine compounds as potent RET kinase inhibitors and antitumor activities against RET rearranged lung adenocarcinoma
M Wang, N Naganna, HO Sintim
Bioorganic chemistry 90, 103052, 2019
Mandates: US National Institutes of Health
Tetrahydro-3 H-pyrazolo [4, 3-a] phenanthridine-based CDK inhibitor
C Opoku-Temeng, N Dayal, DE Hernandez, N Naganna, HO Sintim
Chemical Communications 54 (36), 4521-4524, 2018
Mandates: US National Institutes of Health
3H-Pyrazolo[4,3-f]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo
N Dayal, E Reznickova, DE Hernandez, M Perina, S Torregrosa-Allen, ...
Journal of Medicinal Chemistry 64 (15), 10981-10996, 2021
Mandates: US National Science Foundation, US National Institutes of Health, Helmholtz …
Identification of a Mycobacterium tuberculosis Cyclic Dinucleotide Phosphodiesterase Inhibitor
CW Karanja, KS Yeboah, HO Sintim
ACS infectious diseases 7 (2), 309-317, 2021
Mandates: US National Science Foundation
Fluorescent 2-aminopurine c-di-GMP and GpG analogs as PDE probes
J Zhou, C Opoku-Temeng, HO Sintim
c-di-GMP Signaling: Methods and Protocols, 245-261, 2017
Mandates: US National Science Foundation
Targeting Cyclic Dinucleotide Signaling with Small Molecules
HO Sintim, C Opoku-Temeng
Microbial Cyclic Di-Nucleotide Signaling, 577-591, 2020
Mandates: US National Science Foundation
Synthesis of a Biotinylated Photocleavable Nucleotide Monophosphate for the Preparation of Natively Folded RNAs
Y Luo, HO Sintim, TK Dayie
Methods in Enzymology 549, 115-131, 2014
Mandates: US National Institutes of Health
Available somewhere: 76
Differential radial capillary action of ligand assay for high-throughput detection of protein-metabolite interactions
KG Roelofs, J Wang, HO Sintim, VT Lee
Proceedings of the National Academy of Sciences 108 (37), 15528-15533, 2011
Mandates: US National Institutes of Health
STING ligand c-di-GMP improves cancer vaccination against metastatic breast cancer
D Chandra, W Quispe-Tintaya, A Jahangir, D Asafu-Adjei, I Ramos, ...
Cancer immunology research 2 (9), 901-910, 2014
Mandates: US National Institutes of Health
Unraveling curcumin degradation: autoxidation proceeds through spiroepoxide and vinylether intermediates en route to the main bicyclopentadione
ON Gordon, PB Luis, HO Sintim, C Schneider
Journal of Biological Chemistry 290 (8), 4817-4828, 2015
Mandates: US National Institutes of Health
Oligoribonuclease is the primary degradative enzyme for pGpG in Pseudomonas aeruginosa that is required for cyclic-di-GMP turnover
MW Orr, GP Donaldson, GB Severin, J Wang, HO Sintim, CM Waters, ...
Proceedings of the National Academy of Sciences 112 (36), E5048-E5057, 2015
Mandates: US National Institutes of Health
Fluorescence, phosphorescence, and chemiluminescence
N Siraj, B El-Zahab, S Hamdan, TE Karam, LH Haber, M Li, SO Fakayode, ...
Analytical chemistry 88 (1), 170-202, 2016
Mandates: US National Science Foundation
Cyclic dinucleotide (c-di-GMP, c-di-AMP, and cGAMP) signalings have come of age to be inhibited by small molecules
C Opoku-Temeng, J Zhou, Y Zheng, J Su, HO Sintim
Chemical Communications 52 (60), 9327-9342, 2016
Mandates: US National Science Foundation
Evidence of link between quorum sensing and sugar metabolism in Escherichia coli revealed via cocrystal structures of LsrK and HPr
JH Ha, P Hauk, K Cho, Y Eo, X Ma, K Stephens, S Cha, M Jeong, JY Suh, ...
Science advances 4 (6), eaar7063, 2018
Mandates: US Department of Defense, US National Institutes of Health
Small molecule inhibitors of AI-2 signaling in bacteria: state-of-the-art and future perspectives for anti-quorum sensing agents
M Guo, S Gamby, Y Zheng, HO Sintim
International journal of molecular sciences 14 (9), 17694-17728, 2013
Mandates: US National Institutes of Health
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