| In situ capture of chromatin interactions by biotinylated dCas9 X Liu, Y Zhang, Y Chen, M Li, F Zhou, K Li, H Cao, M Ni, Y Liu, Z Gu, ... Cell 170 (5), 1028-1043. e19, 2017 | 299 | 2017 |
| CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells J Kim, Z Hu, L Cai, K Li, E Choi, B Faubert, D Bezwada, ... Nature 546 (7656), 168-172, 2017 | 273 | 2017 |
| Dissecting super-enhancer hierarchy based on chromatin interactions J Huang, K Li, W Cai, X Liu, Y Zhang, SH Orkin, J Xu, GC Yuan Nature communications 9 (1), 943, 2018 | 225 | 2018 |
| Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing K Li, Y Liu, H Cao, Y Zhang, Z Gu, X Liu, A Yu, P Kaphle, KE Dickerson, ... Nature communications 11 (1), 485, 2020 | 196 | 2020 |
| Inosine monophosphate dehydrogenase dependence in a subset of small cell lung cancers F Huang, M Ni, MD Chalishazar, KE Huffman, J Kim, L Cai, X Shi, F Cai, ... Cell metabolism 28 (3), 369-382. e5, 2018 | 172 | 2018 |
| Loss of EZH2 reprograms BCAA metabolism to drive leukemic transformation Z Gu, Y Liu, F Cai, MK Patrick, J Zmajkovic, H Cao, Y Zhang, A Tasdogan, ... Cancer discovery 9 (9), 1228-1247, 2019 | 136 | 2019 |
| The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer J Kim, HM Lee, F Cai, B Ko, C Yang, EL Lieu, N Muhammad, S Rhyne, ... Nature metabolism 2 (12), 1401-1412, 2020 | 94 | 2020 |
| Simulated microgravity alters the metastatic potential of a human lung adenocarcinoma cell line D Chang, H Xu, Y Guo, X Jiang, Y Liu, K Li, C Pan, M Yuan, J Wang, T Li, ... In Vitro Cellular & Developmental Biology-Animal 49, 170-177, 2013 | 50 | 2013 |
| Genome and epigenome editing identify CCR9 and SLC6A20 as target genes at the 3p21.31 locus associated with severe COVID-19 Y Yao, F Ye, K Li, P Xu, W Tan, Q Feng, S Rao Signal Transduction and Targeted Therapy 6 (1), 85, 2021 | 47 | 2021 |
| Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small-cell lung cancer F Huang, KE Huffman, Z Wang, X Wang, K Li, F Cai, C Yang, L Cai, ... The Journal of clinical investigation 131 (1), 2021 | 40 | 2021 |
| Noncoding variants connect enhancer dysregulation with nuclear receptor signaling in hematopoietic malignancies K Li, Y Zhang, X Liu, Y Liu, Z Gu, H Cao, KE Dickerson, M Chen, W Chen, ... Cancer discovery 10 (5), 724-745, 2020 | 32 | 2020 |
| Lung metastasis of pancreatic carcinoma is regulated by TGFβ signaling L Song, P Wang, Y Tian, D Chang, K Li, Y Fan, J Shen, H Du, R Mi, X Bian, ... Tumor Biology 36, 2271-2276, 2015 | 9 | 2015 |
| Innovative insights into extrachromosomal circular DNAs in gynecologic tumors and reproduction N Wu, L Wei, Z Zhu, Q Liu, K Li, F Mao, J Qiao, X Zhao Protein & Cell 15 (1), 6-20, 2024 | 5 | 2024 |
| The emergence of influenza B as a major respiratory pathogen in the absence of COVID-19 during the 2021–2022 flu season in China D Chang, M Lin, N Song, Z Zhu, J Gao, S Li, H Liu, DZ Liu, Y Zhang, ... Virology Journal 20 (1), 189, 2023 | 4 | 2023 |
| PIEZO1 mechanically regulates the antitumour cytotoxicity of T lymphocytes R Pang, W Sun, Y Yang, D Wen, F Lin, D Wang, K Li, N Zhang, J Liang, ... Nature biomedical engineering, 1-15, 2024 | 3 | 2024 |
| High-throughput functional screen identifies YWHAZ as a key regulator of pancreatic cancer metastasis F Cao, Y Jiang, L Chang, H Du, D Chang, C Pan, X Huang, D Yu, ... Cell Death & Disease 14 (7), 431, 2023 | 3 | 2023 |
| Annotation and evaluation of base editing outcomes in multiple cell types using CRISPRbase J Fan, L Shi, Q Liu, Z Zhu, F Wang, R Song, J Su, D Zhou, X Chen, K Li, ... Nucleic Acids Research 51 (D1), D1249-D1256, 2023 | 3 | 2023 |
| Functional annotation of genetic associations by transcriptome-wide association analysis provides insights into neutrophil development regulation Y Yao, J Yang, Q Qin, C Tang, Z Li, L Chen, K Li, C Ren, L Chen, S Rao Communications Biology 3 (1), 790, 2020 | 3 | 2020 |
| CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (vol 546, pg 168, 2017) J Kim, ZP Hu, L Cai, KL Li, E Choi, B Faubert, D Bezwada, ... Nature 569 (7756), E4-E4, 2019 | 3 | 2019 |
| ZFP36 loss-mediated BARX1 stabilization promotes malignant phenotypes by transactivating master oncogenes in NSCLC T Zhang, L Qiu, J Cao, Q Li, L Zhang, G An, J Ni, H Jia, S Li, K Li Cell Death & Disease 14 (8), 527, 2023 | 2 | 2023 |
Jian XUMember, St. Jude Children's Research HospitalVerified email at stjude.org