Articles with public access mandates - Edwin CuppenLearn more
Not available anywhere: 8
Sequential cancer mutations in cultured human intestinal stem cells
J Drost, RH Van Jaarsveld, B Ponsioen, C Zimberlin, R Van Boxtel, ...
Nature 521 (7550), 43-47, 2015
Mandates: Netherlands Organisation for Health Research and Development, Dutch Cancer …
Measuring mutation accumulation in single human adult stem cells by whole-genome sequencing of organoid cultures
M Jager, F Blokzijl, V Sasselli, S Boymans, R Janssen, N Besselink, ...
Nature protocols 13 (1), 59-78, 2018
Mandates: Netherlands Organisation for Scientific Research, Worldwide Cancer Research, UK
Clinical utility of whole-genome sequencing in precision oncology
R Rosenquist, E Cuppen, R Buettner, C Caldas, H Dreau, O Elemento, ...
Seminars in Cancer Biology 84, 32-39, 2022
Mandates: Knut and Alice Wallenberg Foundation, Swedish Research Council, Cancer …
Detailed imaging and genetic analysis reveal a secondary BRAFL505H resistance mutation and extensive intrapatient heterogeneity in metastatic BRAF mutant …
M Hoogstraat, CG Gadellaa‐van Hooijdonk, I Ubink, NJM Besselink, ...
Pigment cell & melanoma research 28 (3), 318-323, 2015
Mandates: Dutch Cancer Society
Clinical interpretation of whole-genome and whole-transcriptome sequencing for precision oncology
V Jobanputra, KO Wrzeszczynski, R Buttner, C Caldas, E Cuppen, ...
Seminars in Cancer Biology 84, 23-31, 2022
Mandates: US National Institutes of Health, Cancer Research UK, UK Medical Research …
Single nucleotide polymorphism (SNP) panels for rapid positional cloning in zebrafish
MD Clark, V Guryev, E de Bruijn, IJ Nijman, M Tada, C Wilson, ...
Methods in cell biology 104, 219-235, 2011
Mandates: US National Institutes of Health
The 1+ Million Genomes Minimal Dataset for Cancer
M Riba, C Sala, AC Culhane, Å Flobak, A Patocs, K Boye, K Plevova, ...
Nature Genetics, 1-4, 2024
Mandates: European Commission
Optimized whole-genome sequencing workflow for tumor diagnostics in routine pathology practice
KG Samsom, LJW Bosch, LJ Schipper, D Schout, P Roepman, ...
Nature protocols 19 (3), 700-726, 2024
Mandates: Netherlands Organisation for Health Research and Development
Available somewhere: 142
Organoid models of human and mouse ductal pancreatic cancer
SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ...
Cell 160 (1), 324-338, 2015
Mandates: US Department of Energy, US National Institutes of Health, Swedish Research …
SARS-CoV-2 productively infects human gut enterocytes
MM Lamers, J Beumer, J van der Vaart, K Knoops, J Puschhof, ...
Science 369 (6499), 50-54, 2020
Mandates: Netherlands Organisation for Scientific Research, European Commission
Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients
G Schwank, BK Koo, V Sasselli, JF Dekkers, I Heo, T Demircan, N Sasaki, ...
Cell stem cell 13 (6), 653-658, 2013
Mandates: Swiss National Science Foundation, Wellcome Trust, European Commission …
A living biobank of breast cancer organoids captures disease heterogeneity
N Sachs, J De Ligt, O Kopper, E Gogola, G Bounova, F Weeber, ...
Cell 172 (1), 373-386. e10, 2018
Mandates: Netherlands Organisation for Scientific Research
Long-term culture of genome-stable bipotent stem cells from adult human liver
M Huch, H Gehart, R Van Boxtel, K Hamer, F Blokzijl, MMA Verstegen, ...
Cell 160 (1), 299-312, 2015
Mandates: Wellcome Trust, Netherlands Organisation for Health Research and Development
Tissue-specific mutation accumulation in human adult stem cells during life
F Blokzijl, J De Ligt, M Jager, V Sasselli, S Roerink, N Sasaki, M Huch, ...
Nature 538 (7624), 260-264, 2016
Mandates: Netherlands Organisation for Scientific Research, Cancer Research UK …
Pan-cancer whole-genome analyses of metastatic solid tumours
P Priestley, J Baber, MP Lolkema, N Steeghs, E de Bruijn, C Shale, ...
Nature 575 (7781), 210-216, 2019
Mandates: Dutch Cancer Society
Long‐term expanding human airway organoids for disease modeling
N Sachs, A Papaspyropoulos, DD Zomer‐van Ommen, I Heo, L Böttinger, ...
The EMBO journal 38 (4), e100300, 2019
Mandates: Netherlands Organisation for Scientific Research, Netherlands Organisation …
Mutational signature in colorectal cancer caused by genotoxic pks+E. coli
C Pleguezuelos-Manzano, J Puschhof, A Rosendahl Huber, A van Hoeck, ...
Nature 580 (7802), 269-273, 2020
Mandates: US National Institutes of Health, Howard Hughes Medical Institute …
Identification of multipotent luminal progenitor cells in human prostate organoid cultures
WR Karthaus, PJ Iaquinta, J Drost, A Gracanin, R Van Boxtel, J Wongvipat, ...
Cell 159 (1), 163-175, 2014
Mandates: US National Institutes of Health, Netherlands Organisation for Health …
A systematic genome-wide analysis of zebrafish protein-coding gene function
RNW Kettleborough, EM Busch-Nentwich, SA Harvey, CM Dooley, ...
Nature 496 (7446), 494-497, 2013
Mandates: US National Institutes of Health, UK Medical Research Council, Wellcome Trust
MutationalPatterns: comprehensive genome-wide analysis of mutational processes
F Blokzijl, R Janssen, R Van Boxtel, E Cuppen
Genome medicine 10, 1-11, 2018
Mandates: Netherlands Organisation for Scientific Research, Netherlands Organisation …
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