Articles with public access mandates - Peter LeadlayLearn more
Not available anywhere: 9
A common origin for guanidinobutanoate starter units in antifungal natural products.
H Hong, T Fill, PF Leadlay
Angewandte Chemie 125 (49), 2013
Mandates: UK Biotechnology and Biological Sciences Research Council
Substrate specificity of the acyl transferase domains of EpoC from the epothilone polyketide synthase
H Petković, A Sandmann, IR Challis, HJ Hecht, B Silakowski, L Low, ...
Organic & biomolecular chemistry 6 (3), 500-506, 2008
Mandates: German Research Foundation
A Flavin-Dependent Decarboxylase–Dehydrogenase–Monooxygenase Assembles the Warhead of α, β-Epoxyketone Proteasome Inhibitors
D Zabala, JW Cartwright, DM Roberts, BJC Law, L Song, M Samborskyy, ...
Journal of the American Chemical Society 138 (13), 4342-4345, 2016
Mandates: UK Biotechnology and Biological Sciences Research Council
Directed accumulation of anticancer depsipeptides by characterization of neoantimycins biosynthetic pathway and an NADPH-dependent reductase
Y Zhou, X Lin, SR Williams, L Liu, Y Shen, SP Wang, F Sun, S Xu, H Deng, ...
ACS Chemical Biology 13 (8), 2153-2160, 2018
Mandates: National Natural Science Foundation of China
Isoafricanol synthase from Streptomyces malaysiensis
P Rabe, M Samborskyy, PF Leadlay, JS Dickschat
Organic & Biomolecular Chemistry 15 (11), 2353-2358, 2017
Mandates: German Research Foundation
Crystal structure of GenD2, an NAD-dependent oxidoreductase involved in the biosynthesis of gentamicin
NC de Araújo, PS Bury, MT Tavares, F Huang, R Parise-Filho, P Leadlay, ...
ACS chemical biology 14 (5), 925-933, 2019
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Medical …
Efophylins A and B, Two C2-Asymmetric Macrodiolide Immunosuppressants from Streptomyces malaysiensis
J Xu, X Zhang, F Huang, G Li, PF Leadlay
Journal of Natural Products 84 (5), 1579-1586, 2021
Mandates: National Natural Science Foundation of China, UK Biotechnology and …
Hidden Specificities in Enzyme Catalysis: Structural Basis of Substrate Structure‐Selectivity Relationship of a Ketoreductase
M Häckh, X Lucas, M Marolt, PF Leadlay, M Müller, S Günther, S Lüdeke
ChemBioChem 20 (9), 1150-1154, 2019
Mandates: German Research Foundation
Efomycine U, a new C2-asymmetric elaiophylin derivative from Streptomyces malaysiensis DSM 4137
J Xu, J Wu, D Zhou, X Zhang, PF Leadlay
Natural Product Research, 1-6, 2023
Mandates: National Natural Science Foundation of China
Available somewhere: 41
Site-specific recombination strategies for engineering actinomycete genomes
S Herrmann, T Siegl, M Luzhetska, L Petzke, C Jilg, E Welle, A Erb, ...
Applied and environmental microbiology 78 (6), 1804-1812, 2012
Mandates: German Research Foundation
Recent advances in the field of bioactive tetronates
L Vieweg, S Reichau, R Schobert, PF Leadlay, RD Süssmuth
Natural product reports 31 (11), 1554-1584, 2014
Mandates: German Research Foundation, UK Biotechnology and Biological Sciences …
Diversity oriented biosynthesis via accelerated evolution of modular gene clusters
A Wlodek, SG Kendrew, NJ Coates, A Hold, J Pogwizd, S Rudder, ...
Nature communications 8 (1), 1206, 2017
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Research …
In vitro reconstruction of tetronate RK-682 biosynthesis
Y Sun, F Hahn, Y Demydchuk, J Chettle, M Tosin, H Osada, PF Leadlay
Nature chemical biology 6 (2), 99-101, 2010
Mandates: German Research Foundation
Delineating the biosynthesis of gentamicin X2, the common precursor of the gentamicin C antibiotic complex
C Huang, F Huang, E Moison, J Guo, X Jian, X Duan, Z Deng, PF Leadlay, ...
Chemistry & Biology 22 (2), 251-261, 2015
Mandates: Bill & Melinda Gates Foundation, National Natural Science Foundation of …
Iterative mechanism of macrodiolide formation in the anticancer compound conglobatin
Y Zhou, AC Murphy, M Samborskyy, P Prediger, LC Dias, PF Leadlay
Chemistry & biology 22 (6), 745-754, 2015
Mandates: UK Biotechnology and Biological Sciences Research Council
Unusual acetylation–elimination in the formation of tetronate antibiotics
C Kanchanabanca, W Tao, H Hong, Y Liu, F Hahn, M Samborskyy, ...
Angewandte Chemie 125 (22), 5897-5900, 2013
Mandates: German Research Foundation, UK Biotechnology and Biological Sciences …
Methyltransferases of gentamicin biosynthesis
S Li, J Guo, A Reva, F Huang, B Xiong, Y Liu, Z Deng, PF Leadlay, Y Sun
Proceedings of the National Academy of Sciences 115 (6), 1340-1345, 2018
Mandates: National Natural Science Foundation of China, UK Medical Research Council
Specificity and promiscuity at the branch point in gentamicin biosynthesis
J Guo, F Huang, C Huang, X Duan, X Jian, F Leeper, Z Deng, PF Leadlay, ...
Chemistry & biology 21 (5), 608-618, 2014
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Medical …
Structure of the glycosyltransferase EryCIII in complex with its activating P450 homologue EryCII
MC Moncrieffe, MJ Fernandez, D Spiteller, H Matsumura, NJ Gay, ...
Journal of molecular biology 415 (1), 92-101, 2012
Mandates: Government of Spain
Broadening substrate specificity of a chain-extending ketosynthase through a single active-site mutation
AC Murphy, H Hong, S Vance, RW Broadhurst, PF Leadlay
Chemical Communications 52 (54), 8373-8376, 2016
Mandates: UK Biotechnology and Biological Sciences Research Council, Wellcome Trust
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