| Antidepressant acts on astrocytes leading to an increase in the expression of neurotrophic/growth factors: differential regulation of FGF-2 by noradrenaline N Kajitani, K Hisaoka-Nakashima, N Morioka, M Okada-Tsuchioka, ... PLoS One 7 (12), e51197, 2012 | 97 | 2012 |
| Amitriptyline up‐regulates connexin43‐gap junction in rat cultured cortical astrocytes via activation of the p 38 and c‐Fos/AP‐1 signalling pathway N Morioka, K Suekama, FF Zhang, N Kajitani, K Hisaoka‐Nakashima, ... British journal of pharmacology 171 (11), 2854-2867, 2014 | 81 | 2014 |
| Tricyclic antidepressant amitriptyline activates fibroblast growth factor receptor signaling in glial cells: involvement in glial cell line-derived neurotrophic factor production K Hisaoka, M Tsuchioka, R Yano, N Maeda, N Kajitani, N Morioka, ... Journal of Biological Chemistry 286 (24), 21118-21128, 2011 | 70 | 2011 |
| Amitriptyline induces brain-derived neurotrophic factor (BDNF) mRNA expression through ERK-dependent modulation of multiple BDNF mRNA variants in primary cultured rat cortical … K Hisaoka-Nakashima, N Kajitani, M Kaneko, T Shigetou, M Kasai, ... Brain research 1634, 57-67, 2016 | 66 | 2016 |
| Altered serum levels of matrix metalloproteinase-2,-9 in response to electroconvulsive therapy for mood disorders C Shibasaki, M Takebayashi, K Itagaki, H Abe, N Kajitani, ... International Journal of Neuropsychopharmacology 19 (9), pyw019, 2016 | 48 | 2016 |
| Tricyclic antidepressant amitriptyline-induced glial cell line-derived neurotrophic factor production involves pertussis toxin-sensitive Gαi/o activation in astroglial cells K Hisaoka-Nakashima, K Miyano, C Matsumoto, N Kajitani, H Abe, ... Journal of Biological Chemistry 290 (22), 13678-13691, 2015 | 47 | 2015 |
| Electroconvulsive seizure induces thrombospondin-1 in the adult rat hippocampus M Okada-Tsuchioka, M Segawa, N Kajitani, K Hisaoka-Nakashima, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 48, 236-244, 2014 | 37 | 2014 |
| Factors associated with relapse after a response to electroconvulsive therapy in unipolar versus bipolar depression K Itagaki, M Takebayashi, C Shibasaki, N Kajitani, H Abe, ... Journal of affective disorders 208, 113-119, 2017 | 33 | 2017 |
| Identification of lysophosphatidic acid receptor 1 in astroglial cells as a target for glial cell line-derived neurotrophic factor expression induced by antidepressants N Kajitani, K Miyano, M Okada-Tsuchioka, H Abe, K Itagaki, ... Journal of Biological Chemistry 291 (53), 27364-27370, 2016 | 30 | 2016 |
| Increased matrix metalloproteinases in cerebrospinal fluids of patients with major depressive disorder and schizophrenia W Omori, K Hattori, N Kajitani, M Okada-Tsuchioka, S Boku, H Kunugi, ... International Journal of Neuropsychopharmacology 23 (11), 713-720, 2020 | 26 | 2020 |
| Shared preventive factors associated with relapse after a response to electroconvulsive therapy in four major psychiatric disorders W Omori, K Itagaki, N Kajitani, H Abe, M Okada‐Tsuchioka, Y Okamoto, ... Psychiatry and clinical neurosciences 73 (8), 494-500, 2019 | 21 | 2019 |
| Fibroblast growth factor 2 mRNA expression evoked by amitriptyline involves extracellular signal‐regulated kinase‐dependent early growth response 1 production in rat primary … N Kajitani, K Hisaoka‐Nakashima, M Okada‐Tsuchioka, M Hosoi, ... Journal of Neurochemistry 135 (1), 27-37, 2015 | 21 | 2015 |
| Tricyclic antidepressant amitriptyline indirectly increases the proliferation of adult dentate gyrus-derived neural precursors: an involvement of astrocytes S Boku, K Hisaoka-Nakashima, S Nakagawa, A Kato, N Kajitani, T Inoue, ... Plos one 8 (11), e79371, 2013 | 20 | 2013 |
| Possible association between serum matrix metalloproteinase-9 (MMP-9) levels and relapse in depressed patients following electroconvulsive therapy (ECT) C Shibasaki, K Itagaki, H Abe, N Kajitani, M Okada-Tsuchioka, ... International Journal of Neuropsychopharmacology 21 (3), 236-241, 2018 | 18 | 2018 |
| Reduced serum and cerebrospinal fluid levels of autotaxin in major depressive disorder K Itagaki, M Takebayashi, H Abe, C Shibasaki, N Kajitani, ... International Journal of Neuropsychopharmacology 22 (4), 261-269, 2019 | 17 | 2019 |
| Reduced cerebrospinal fluid levels of lysophosphatidic acid docosahexaenoic acid in patients with major depressive disorder and schizophrenia W Omori, K Kano, K Hattori, N Kajitani, M Okada-Tsuchioka, S Boku, ... International Journal of Neuropsychopharmacology 24 (12), 948-955, 2021 | 11 | 2021 |
| Decreased serum levels of thrombospondin‐1 in female depressed patients M Okada‐Tsuchioka, W Omori, N Kajitani, C Shibasaki, K Itagaki, ... Neuropsychopharmacology Reports 40 (1), 39-45, 2020 | 11 | 2020 |
| The expression of glial cell line-derived neurotrophic factor mRNA by antidepressants involves matrix metalloproteinase-9 activation in rat astroglial cells H Abe, K Hisaoka-Nakashima, N Kajitani, M Okada-Tsuchioka, R Yano, ... Biochemical and biophysical research communications 479 (4), 907-912, 2016 | 9 | 2016 |
| Tetraspanin heterogeneity of small extracellular vesicles in human biofluids and brain tissue M Okada-Tsuchioka, N Kajitani, W Omori, T Kurashige, S Boku, ... Biochemical and Biophysical Research Communications 627, 146-151, 2022 | 8 | 2022 |
| G protein-biased LPAR1 agonism of prototypic antidepressants: Implication in the identification of novel therapeutic target for depression N Kajitani, M Okada-Tsuchioka, A Inoue, K Miyano, T Masuda, S Boku, ... Neuropsychopharmacology 49 (3), 561-572, 2024 | 6 | 2024 |
Shuken BokuAssociate Professor, Department of Neuropsychiatry, Kumamoto University Faculty of Life SciencesVerified email at kuh.kumamoto-u.ac.jp
