STINGel: Controlled release of a cyclic dinucleotide for enhanced cancer immunotherapy DG Leach, N Dharmaraj, SL Piotrowski, TL Lopez-Silva, YL Lei, ... Biomaterials 163, 67-75, 2018 | 188 | 2018 |
Sequence-specific, nanomolar peptide binding via cucurbit [8] uril-induced folding and inclusion of neighboring side chains LC Smith, DG Leach, BE Blaylock, OA Ali, AR Urbach Journal of the American Chemical Society 137 (10), 3663-3669, 2015 | 173 | 2015 |
Advances in immunotherapy delivery from implantable and injectable biomaterials DG Leach, S Young, JD Hartgerink Acta biomaterialia 88, 15-31, 2019 | 163 | 2019 |
Multidomain peptide hydrogel accelerates healing of full-thickness wounds in diabetic mice NC Carrejo, AN Moore, TL Lopez Silva, DG Leach, IC Li, DR Walker, ... ACS biomaterials science & engineering 4 (4), 1386-1396, 2018 | 115 | 2018 |
Chemical functionality of multidomain peptide hydrogels governs early host immune response TL Lopez-Silva, DG Leach, A Azares, IC Li, DG Woodside, JD Hartgerink Biomaterials 231, 119667, 2020 | 108 | 2020 |
Influence of injection technique, drug formulation and tumor microenvironment on intratumoral immunotherapy delivery and efficacy NM Muñoz, M Williams, K Dixon, C Dupuis, A McWatters, R Avritscher, ... Journal for immunotherapy of cancer 9 (2), 2021 | 94 | 2021 |
Self-assembling multidomain peptides: design and characterization of neutral peptide-based materials with pH and ionic strength independent self-assembly TL Lopez-Silva, DG Leach, IC Li, X Wang, JD Hartgerink ACS biomaterials science & engineering 5 (2), 977-985, 2018 | 49 | 2018 |
Biomaterial-facilitated immunotherapy for established oral cancers DG Leach, N Dharmaraj, TL Lopez-Silva, JR Venzor, BH Pogostin, ... ACS biomaterials science & engineering 7 (2), 415-421, 2021 | 31 | 2021 |
Drug-mimicking nanofibrous peptide hydrogel for inhibition of inducible nitric oxide synthase DG Leach, JM Newton, MA Florez, TL Lopez-Silva, AA Jones, S Young, ... ACS biomaterials science & engineering 5 (12), 6755-6765, 2019 | 21 | 2019 |
Local anti–PD-1 delivery prevents progression of premalignant lesions in a 4NQO-oral carcinogenesis mouse model Y Shi, T Xie, DG Leach, B Wang, S Young, AA Osman, AG Sikora, X Ren, ... Cancer Prevention Research 14 (8), 767-778, 2021 | 17 | 2021 |
Rock-Fluid Interaction and Its Application in Unconventional Production W Wang, W Wei, D Leach, C Yan, K Spilker SPE/AAPG/SEG Unconventional Resources Technology Conference 2020, 2020 | 8 | 2020 |
Molecular deep dive into oilfield microbiologically influenced corrosion: A detailed case study of MIC failure analysis in an unconventional asset DG Leach, W Wang, C Yan, D Mattis, R MacLeod, W Wei AMPP CORROSION, D031S027R002, 2022 | 1 | 2022 |
Bacteria in Hydraulic Fracturing: Impacts of Water Chemistry and Microbiology on Unconventional Operations and Rock Fluid Interactions DG Leach, M Hefta, W Wei SPE/AAPG/SEG Unconventional Resources Technology Conference, D021S036R001, 2024 | | 2024 |
Overview of FeS Scale Control and Treatment Under Challenging Applications H Lu, W Wei, W Wang, D Leach, C Yan SPE International Oilfield Scale Conference and Exhibition?, D023S008R002, 2024 | | 2024 |
Hydrogel delivery of sting immunotherapy for treatment cancer S Young, D Leach, JD Hartgerink US Patent 11,969,499, 2024 | | 2024 |
Stimulator of Interferon Genes Pathway Activation through the Controlled Release of STINGel Mediates Analgesia and Anti-Cancer Effects in Oral Squamous Cell Carcinoma MP Dong, N Dharmaraj, E Kaminagakura, J Xue, DG Leach, ... Biomedicines 12 (4), 920, 2024 | | 2024 |
Enhancing water chemistry for improved well performance W Wang, W Wei, Y Tang, JC Visser, DG Leach, H Lu, SKK Lattimer US Patent App. 18/319,884, 2023 | | 2023 |
Chemical Control of H2S for Unconventional Production: Performance Evaluation of Triazine and Non-Triazine H2S Scavengers in Challenging Environments D Leach, C Yan, W Wang, W Wei SPE International Conference on Oilfield Chemistry?, D021S008R001, 2023 | | 2023 |
Impact of subsurface fluid chemistry on microbial growth, corrosion, and reservoir souring in unconventional assets DG Leach, W Wang, C Yan, R MacLeod, D Mattis, W Wei Unconventional Resources Technology Conference, 20–22 June 2022, 1676-1695, 2022 | | 2022 |
Neutral multidomain peptide hydrogels and uses thereof J Hartgerink, D Leach, T Lopez-silva US Patent App. 17/285,767, 2021 | | 2021 |