Restoring cystic fibrosis transmembrane conductance regulator function reduces airway bacteria and inflammation in people with cystic fibrosis and chronic lung infections KB Hisert, SL Heltshe, C Pope, P Jorth, X Wu, RM Edwards, M Radey, ... American journal of respiratory and critical care medicine 195 (12), 1617-1628, 2017 | 345 | 2017 |
Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs DA Stoltz, T Rokhlina, SE Ernst, AA Pezzulo, LS Ostedgaard, PH Karp, ... The Journal of clinical investigation 123 (6), 2685-2693, 2013 | 145 | 2013 |
Assessing mucociliary transport of single particles in vivo shows variable speed and preference for the ventral trachea in newborn pigs MJ Hoegger, M Awadalla, E Namati, OA Itani, AJ Fischer, AJ Tucker, ... Proceedings of the National Academy of Sciences 111 (6), 2355-2360, 2014 | 84 | 2014 |
Air trapping and airflow obstruction in newborn cystic fibrosis piglets RJ Adam, AS Michalski, C Bauer, MH Abou Alaiwa, TJ Gross, ... American journal of respiratory and critical care medicine 188 (12), 1434-1441, 2013 | 77 | 2013 |
Tracheomalacia is associated with lower FEV1 and Pseudomonas acquisition in children with CF AJ Fischer, SB Singh, RJ Adam, DA Stoltz, CF Baranano, S Kao, ... Pediatric pulmonology 49 (10), 960-970, 2014 | 62 | 2014 |
Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs DK Meyerholz, DA Stoltz, ND Gansemer, SE Ernst, DP Cook, MD Strub, ... Laboratory Investigation 98 (6), 825-838, 2018 | 46 | 2018 |
Acute administration of ivacaftor to people with cystic fibrosis and a G551D-CFTR mutation reveals smooth muscle abnormalities RJ Adam, KB Hisert, JD Dodd, B Grogan, JL Launspach, JK Barnes, ... JCI insight 1 (4), 2016 | 43 | 2016 |
Early airway structural changes in cystic fibrosis pigs as a determinant of particle distribution and deposition M Awadalla, S Miyawaki, MH Abou Alaiwa, RJ Adam, DC Bouzek, ... Annals of biomedical engineering 42, 915-927, 2014 | 31 | 2014 |
Restoring CFTR function reduces airway bacteria and inflammation in people with cystic fibrosis and chronic lung infections KB Hisert, SL Heltshe, C Pope, P Jorth, X Wu, RM Edwards, M Radey, ... Am J Respir Crit Care Med 195 (12), 1617-28, 2017 | 30 | 2017 |
Integrin α6β4 identifies human distal lung epithelial progenitor cells with potential as a cell-based therapy for cystic fibrosis lung disease X Li, N Rossen, PL Sinn, AL Hornick, BR Steines, PH Karp, SE Ernst, ... PloS one 8 (12), e83624, 2013 | 29 | 2013 |
Acid-sensing ion channel 1a contributes to airway hyperreactivity in mice LR Reznikov, DK Meyerholz, RJ Adam, M Abou Alaiwa, O Jaffer, ... PLoS One 11 (11), e0166089, 2016 | 26 | 2016 |
Sonographic evidence of abnormal tracheal cartilage ring structure in cystic fibrosis A Diwakar, RJ Adam, AS Michalski, MM Tamegnon, AJ Fischer, ... The Laryngoscope 125 (10), 2398-2404, 2015 | 24 | 2015 |
Comparison of the surgical resection and infarct 5/6 nephrectomy rat models of chronic kidney disease RJ Adam, AC Williams, AJ Kriegel American Journal of Physiology-Renal Physiology 322 (6), F639-F654, 2022 | 18 | 2022 |
CF airway smooth muscle transcriptome reveals a role for PYK2 DP Cook, RJ Adam, K Zarei, B Deonovic, MR Stroik, ND Gansemer, ... JCI insight 2 (17), 2017 | 14 | 2017 |
Computer-aided analysis of airway trees in micro-CT scans of ex vivo porcine lung tissue C Bauer, R Adam, DA Stoltz, RR Beichel Computerized Medical Imaging and Graphics 36 (8), 601-609, 2012 | 14 | 2012 |
Early lung disease exhibits bacteria-dependent and-independent abnormalities in cystic fibrosis pigs DC Bouzek, MH Abou Alaiwa, RJ Adam, AA Pezzulo, LR Reznikov, ... American journal of respiratory and critical care medicine 204 (6), 692-702, 2021 | 13 | 2021 |
Sympathoexcitation in response to cardiac and pulmonary afferent stimulation of TRPA1 channels is attenuated in rats with chronic heart failure RJ Adam, Z Xia, K Pravoverov, J Hong, AJ Case, HD Schultz, SJ Lisco, ... American Journal of Physiology-Heart and Circulatory Physiology 316 (4 …, 2019 | 10 | 2019 |
Cystic fibrosis transmembrane conductance regulator potentiation as a therapeutic strategy for pulmonary edema: a proof-of-concept study in pigs X Li, LGV Buonfiglio, RJ Adam, DA Stoltz, J Zabner, AP Comellas Critical care medicine 45 (12), e1240-e1246, 2017 | 9 | 2017 |
Macrophage activation in stellate ganglia contributes to lung injury‐induced arrhythmogenesis in male rats J Hong, RJ Adam, L Gao, T Hahka, Z Xia, D Wang, TA Nicholas, IH Zucker, ... Acta physiologica 232 (2), e13657, 2021 | 6 | 2021 |
Postnatal airway growth in cystic fibrosis piglets RJ Adam, MH Abou Alaiwa, DC Bouzek, DP Cook, ND Gansemer, PJ Taft, ... Journal of Applied Physiology 123 (3), 526-533, 2017 | 6 | 2017 |