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Xiaofeng Qi
Xiaofeng Qi
Assistant Professor, UT Southwestern Medical Center
Verified email at utsouthwestern.edu
Title
Cited by
Cited by
Year
Structures of human Patched and its complex with native palmitoylated sonic hedgehog
X Qi, P Schmiege, E Coutavas, J Wang, X Li
Nature 560 (7716), 128-132, 2018
1772018
Cryo-EM structure of oxysterol-bound human Smoothened coupled to a heterotrimeric Gi
X Qi, H Liu, B Thompson, J McDonald, C Zhang, X Li
Nature 571 (7764), 279-283, 2019
1512019
A LysM receptor heteromer mediates perception of arbuscular mycorrhizal symbiotic signal in rice
J He, C Zhang, H Dai, H Liu, X Zhang, J Yang, X Chen, Y Zhu, D Wang, ...
Molecular Plant 12 (12), 1561-1576, 2019
1372019
Two Patched molecules engage distinct sites on Hedgehog yielding a signaling-competent complex
X Qi, P Schmiege, E Coutavas, X Li
Science 362 (6410), eaas8843, 2018
1242018
Mechanistic insights into the generation and transduction of hedgehog signaling
X Qi, X Li
Trends in biochemical sciences 45 (5), 397-410, 2020
752020
Structure of nevanimibe-bound tetrameric human ACAT1
T Long, Y Sun, A Hassan, X Qi, X Li
Nature 581 (7808), 339-343, 2020
702020
Structural basis for itraconazole-mediated NPC1 inhibition
T Long, X Qi, A Hassan, Q Liang, JK De Brabander, X Li
Nature communications 11 (1), 152, 2020
692020
Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling
X Qi, L Friedberg, R De Bose-Boyd, T Long, X Li
Nature chemical biology 16 (12), 1368-1375, 2020
672020
Molecular basis of cholesterol efflux via ABCG subfamily transporters
Y Sun, J Wang, T Long, X Qi, L Donnelly, N Elghobashi-Meinhardt, ...
Proceedings of the National Academy of Sciences 118 (34), e2110483118, 2021
582021
Structural basis of intramitochondrial phosphatidic acid transport mediated by U ps1‐M dm35 complex
F Yu, F He, H Yao, C Wang, J Wang, J Li, X Qi, H Xue, J Ding, P Zhang
EMBO reports 16 (7), 813-823, 2015
582015
Mechanisms and inhibition of Porcupine-mediated Wnt acylation
Y Liu, X Qi, L Donnelly, N Elghobashi-Meinhardt, T Long, RW Zhou, ...
Nature 607 (7920), 816-822, 2022
522022
Structure and mechanism of a group-I cobalt energy coupling factor transporter
Z Bao, X Qi, S Hong, K Xu, F He, M Zhang, J Chen, D Chao, W Zhao, D Li, ...
Cell research 27 (5), 675-687, 2017
482017
Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain
H Chen, X Qi, RA Faulkner, MM Schumacher, LM Donnelly, ...
Nature communications 13 (1), 4273, 2022
322022
Structural basis of rifampin inactivation by rifampin phosphotransferase
X Qi, W Lin, M Ma, C Wang, Y He, N He, J Gao, H Zhou, Y Xiao, Y Wang, ...
Proceedings of the National Academy of Sciences 113 (14), 3803-3808, 2016
262016
Marked structural rearrangement of mannose 6-phosphate/IGF2 receptor at different pH environments
R Wang, X Qi, P Schmiege, E Coutavas, X Li
Science Advances 6 (7), eaaz1466, 2020
252020
Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signaling
X Qi, Q Hu, N Elghobashi-Meinhardt, T Long, H Chen, X Li
Cell 186 (23), 5028-5040. e14, 2023
72023
Expression, Purification, and Structure Determination of Human PTCH1–HH-N Complexes
X Qi, P Schmiege, L Esparza, X Li
Hedgehog Signaling: Methods and Protocols, 107-120, 2022
22022
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