| TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal PJ Killela, ZJ Reitman, Y Jiao, C Bettegowda, N Agrawal, LA Diaz Jr, ... Proceedings of the National Academy of Sciences 110 (15), 6021-6026, 2013 | 1570 | 2013 |
| Altered telomeres in tumors with ATRX and DAXX mutations CM Heaphy, RF De Wilde, Y Jiao, AP Klein, BH Edil, C Shi, C Bettegowda, ... Science 333 (6041), 425-425, 2011 | 1194 | 2011 |
| Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas Y Jiao, PJ Killela, ZJ Reitman, BA Rasheed, CM Heaphy, RF De Wilde, ... Oncotarget 3 (7), 709, 2012 | 693 | 2012 |
| Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements MC Haffner, MJ Aryee, A Toubaji, DM Esopi, R Albadine, B Gurel, ... Nature genetics 42 (8), 668-675, 2010 | 676 | 2010 |
| Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway CA Lovejoy, W Li, S Reisenweber, S Thongthip, J Bruno, T De Lange, ... PLoS genetics 8 (7), e1002772, 2012 | 624 | 2012 |
| Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes CM Heaphy, AP Subhawong, SM Hong, MG Goggins, EA Montgomery, ... The American journal of pathology 179 (4), 1608-1615, 2011 | 574 | 2011 |
| Telomerase activity: a prevalent marker of malignant human prostate tissue HJ Sommerfeld, AK Meeker, MA Piatyszek, GS Bova, JW Shay, DS Coffey Cancer research 56 (1), 218-222, 1996 | 565 | 1996 |
| Tracking the clonal origin of lethal prostate cancer MC Haffner, T Mosbruger, DM Esopi, H Fedor, CM Heaphy, DA Walker, ... The Journal of clinical investigation 123 (11), 4918-4922, 2013 | 552 | 2013 |
| Contributions of the large hydrophobic amino acids to the stability of staphylococcal nuclease D Shortle, WE Stites, AK Meeker Biochemistry 29 (35), 8033-8041, 1990 | 536 | 1990 |
| Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing KS Sfanos, TC Bruno, CH Maris, L Xu, CJ Thoburn, AM DeMarzo, ... Clinical Cancer Research 14 (11), 3254-3261, 2008 | 523 | 2008 |
| Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers MC Haffner, A Chaux, AK Meeker, DM Esopi, J Gerber, LG Pellakuru, ... Oncotarget 2 (8), 627, 2011 | 484 | 2011 |
| Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia NT Van Heek, AK Meeker, SE Kern, CJ Yeo, KD Lillemoe, JL Cameron, ... The American journal of pathology 161 (5), 1541-1547, 2002 | 484 | 2002 |
| Telomere length abnormalities occur early in the initiation of epithelial carcinogenesis AK Meeker, JL Hicks, CA Iacobuzio-Donahue, EA Montgomery, ... Clinical Cancer Research 10 (10), 3317-3326, 2004 | 383 | 2004 |
| Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition LR Ferguson, H Chen, AR Collins, M Connell, G Damia, S Dasgupta, ... Seminars in cancer biology 35, S5-S24, 2015 | 382 | 2015 |
| PD-L1 (B7-H1) expression and the immune tumor microenvironment in primary and metastatic breast carcinomas A Cimino-Mathews, E Thompson, JM Taube, X Ye, Y Lu, A Meeker, H Xu, ... Human pathology 47 (1), 52-63, 2016 | 363 | 2016 |
| Mutant forms of staphylococcal nuclease with altered patterns of guanidine hydrochloride and urea denaturation D Shortle, AK Meeker Proteins: Structure, Function, and Bioinformatics 1 (1), 81-89, 1986 | 354 | 1986 |
| Telomere shortening is an early somatic DNA alteration in human prostate tumorigenesis AK Meeker, JL Hicks, EA Platz, GE March, CJ Bennett, MJ Delannoy, ... Cancer research 62 (22), 6405-6409, 2002 | 335 | 2002 |
| Residual structure in large fragments of staphylococcal nuclease: effects of amino acid substitutions D Shortle, AK Meeker Biochemistry 28 (3), 936-944, 1989 | 320 | 1989 |
| Stem cell features of benign and malignant prostate epithelial cells AM De Marzo, WG Nelson, AK Meeker, DS Coffey The Journal of urology 160 (6), 2381-2392, 1998 | 319 | 1998 |
| Prostate stem cell compartments: expression of the cell cycle inhibitor p27Kip1 in normal, hyperplastic, and neoplastic cells AM De Marzo, AK Meeker, JI Epstein, DS Coffey The American journal of pathology 153 (3), 911-919, 1998 | 319 | 1998 |
Angelo M. De Marzo M.D., Ph.D.Professor of Pathology, Urology and Oncology, The Johns Hopkins University School of MedicineVerified email at jhmi.edu