The small intestine converts dietary fructose into glucose and organic acids C Jang, S Hui, W Lu, AJ Cowan, RJ Morscher, G Lee, W Liu, GJ Tesz, ... Cell metabolism 27 (2), 351-361. e3, 2018 | 576 | 2018 |
Conserved MicroRNA miR-8/miR-200 and its target USH/FOG2 control growth by regulating PI3K S Hyun, JH Lee, H Jin, JW Nam, B Namkoong, G Lee, J Chung, VN Kim Cell 139 (6), 1096-1108, 2009 | 349 | 2009 |
The mTORC1/S6K1 pathway regulates glutamine metabolism through the eIF4B-dependent control of c-Myc translation A Csibi, G Lee, SO Yoon, H Tong, D Ilter, I Elia, SM Fendt, TM Roberts, ... Current biology 24 (19), 2274-2280, 2014 | 290 | 2014 |
The PINK1–Parkin pathway is involved in the regulation of mitochondrial remodeling process J Park, G Lee, J Chung Biochemical and biophysical research communications 378 (3), 518-523, 2009 | 207 | 2009 |
Post-transcriptional regulation of de novo lipogenesis by mTORC1-S6K1-SRPK2 signaling G Lee, Y Zheng, S Cho, C Jang, C England, JM Dempsey, Y Yu, X Liu, ... Cell 171 (7), 1545-1558. e18, 2017 | 204 | 2017 |
ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase SB Lee, S Kim, J Lee, J Park, G Lee, Y Kim, JM Kim, J Chung EMBO reports 8 (4), 360-365, 2007 | 194 | 2007 |
A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses D Sun, G Lee, JH Lee, HY Kim, HW Rhee, SY Park, KJ Kim, Y Kim, ... Nature structural & molecular biology 17 (10), 1188-1194, 2010 | 140 | 2010 |
mTORC1 promotes metabolic reprogramming by the suppression of GSK3-dependent Foxk1 phosphorylation L He, AP Gomes, X Wang, SO Yoon, G Lee, MJ Nagiec, S Cho, A Chavez, ... Molecular cell 70 (5), 949-960. e4, 2018 | 136 | 2018 |
The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue S Wada, M Neinast, C Jang, YH Ibrahim, G Lee, A Babu, J Li, A Hoshino, ... Genes & development 30 (22), 2551-2564, 2016 | 124 | 2016 |
The small intestine shields the liver from fructose-induced steatosis C Jang, S Wada, S Yang, B Gosis, X Zeng, Z Zhang, Y Shen, G Lee, ... Nature metabolism 2 (7), 586-593, 2020 | 98 | 2020 |
Mitochondrial one-carbon pathway supports cytosolic folate integrity in cancer cells Y Zheng, TY Lin, G Lee, MN Paddock, J Momb, Z Cheng, Q Li, DL Fei, ... Cell 175 (6), 1546-1560. e17, 2018 | 93 | 2018 |
DNA damage-induced RORα is crucial for p53 stabilization and increased apoptosis H Kim, JM Lee, G Lee, J Bhin, SK Oh, K Kim, KE Pyo, JS Lee, HY Yim, ... Molecular cell 44 (5), 797-810, 2011 | 89 | 2011 |
mTORC1 promotes cell growth via m6A-dependent mRNA degradation S Cho, G Lee, BF Pickering, C Jang, JH Park, L He, L Mathur, SS Kim, ... Molecular cell 81 (10), 2064-2075. e8, 2021 | 76 | 2021 |
mTORC1-chaperonin CCT signaling regulates m6A RNA methylation to suppress autophagy HW Tang, JH Weng, WX Lee, Y Hu, L Gu, S Cho, G Lee, R Binari, C Li, ... Proceedings of the National Academy of Sciences 118 (10), e2021945118, 2021 | 63 | 2021 |
UVRAG is required for organ rotation by regulating Notch endocytosis in Drosophila G Lee, C Liang, G Park, C Jang, JU Jung, J Chung Developmental biology 356 (2), 588-597, 2011 | 48 | 2011 |
Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication TM Yaron, BE Heaton, TM Levy, JL Johnson, TX Jordan, BM Cohen, ... Science signaling 15 (757), eabm0808, 2022 | 45 | 2022 |
Discrete functions of rictor and raptor in cell growth regulation in Drosophila G Lee, J Chung Biochemical and biophysical research communications 357 (4), 1154-1159, 2007 | 44 | 2007 |
Metabolic Control of m6A RNA Modification J Kim, G Lee Metabolites 11 (2), 80, 2021 | 40 | 2021 |
SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2 TM Yaron, BE Heaton, TM Levy, JL Johnson, TX Jordan, BM Cohen, ... | 39 | 2020 |
The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro TM Yaron, BE Heaton, TM Levy, JL Johnson, TX Jordan, BM Cohen, ... BioRxiv, 2020.08. 14.251207, 2020 | 35 | 2020 |