High incidence of DNA mutations and gene amplifications of the ALK gene in advanced sporadic neuroblastoma tumours H Carén, F Abel, P Kogner, T Martinsson Biochemical Journal 416 (2), 153-159, 2008 | 362 | 2008 |
High-risk neuroblastoma tumors with 11q-deletion display a poor prognostic, chromosome instability phenotype with later onset H Carén, H Kryh, M Nethander, RM Sjöberg, C Träger, S Nilsson, ... Proceedings of the National Academy of Sciences 107 (9), 4323-4328, 2010 | 280 | 2010 |
Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner SH Stricker, A Feber, PG Engström, H Carén, KM Kurian, Y Takashima, ... Genes & development 27 (6), 654-669, 2013 | 165 | 2013 |
The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells G Mazor, L Levin, D Picard, U Ahmadov, H Carén, A Borkhardt, ... Cell death & disease 10 (3), 246, 2019 | 140 | 2019 |
Sense-antisense lncRNA pair encoded by locus 6p22. 3 determines neuroblastoma susceptibility via the USP36-CHD7-SOX9 regulatory axis T Mondal, PK Juvvuna, A Kirkeby, S Mitra, ST Kosalai, L Traxler, ... Cancer cell 33 (3), 417-434. e7, 2018 | 135 | 2018 |
High-resolution array copy number analyses for detection of deletion, gain, amplification and copy-neutral LOH in primary neuroblastoma tumors: four cases of homozygous … H Carén, J Erichsen, L Olsson, C Enerbäck, RM Sjöberg, J Abrahamsson, ... BMC genomics 9, 1-13, 2008 | 130 | 2008 |
Glioblastoma stem cells respond to differentiation cues but fail to undergo commitment and terminal cell-cycle arrest H Carén, SH Stricker, H Bulstrode, S Gagrica, E Johnstone, TE Bartlett, ... Stem cell reports 5 (5), 829-842, 2015 | 121 | 2015 |
Intratumor DNA methylation heterogeneity in glioblastoma: implications for DNA methylation-based classification A Wenger, S Ferreyra Vega, T Kling, TO Bontell, AS Jakola, H Carén Neuro-oncology 21 (5), 616-627, 2019 | 116 | 2019 |
Identification of epigenetically regulated genes that predict patient outcome in neuroblastoma H Carén, A Djos, M Nethander, RM Sjöberg, P Kogner, C Enström, ... BMC cancer 11, 1-11, 2011 | 111 | 2011 |
Introduction of in vitro transcribed ENO1 mRNA into neuroblastoma cells induces cell death K Ejeskär, C Krona, H Carén, F Zaibak, L Li, T Martinsson, PA Ioannou BMC cancer 5, 1-14, 2005 | 106 | 2005 |
Appearance of the novel activating F1174S ALK mutation in neuroblastoma correlates with aggressive tumor progression and unresponsiveness to therapy T Martinsson, T Eriksson, J Abrahamsson, H Caren, M Hansson, ... Cancer research 71 (1), 98-105, 2011 | 97 | 2011 |
The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma A Djos, T Martinsson, P Kogner, H Carén Molecular cancer 11, 1-13, 2012 | 88 | 2012 |
Genome-wide methylation profiling identifies novel methylated genes in neuroblastoma tumors M Olsson, S Beck, P Kogner, T Martinsson, H Carén Epigenetics 11 (1), 74-84, 2016 | 84 | 2016 |
Genetic and epigenetic changes in the common 1p36 deletion in neuroblastoma tumours H Carén, S Fransson, K Ejeskär, P Kogner, T Martinsson British journal of cancer 97 (10), 1416-1424, 2007 | 80 | 2007 |
COX-2 gene expression in colon cancer tissue related to regulating factors and promoter methylation status AG Asting, H Carén, M Andersson, C Lönnroth, K Lagerstedt, K Lundholm BMC cancer 11, 1-10, 2011 | 69 | 2011 |
Validation of the MethylationEPIC BeadChip for fresh-frozen and formalin-fixed paraffin-embedded tumours T Kling, A Wenger, S Beck, H Carén Clinical epigenetics 9, 1-6, 2017 | 68 | 2017 |
The good, the bad and the ugly: epigenetic mechanisms in glioblastoma H Carén, SM Pollard, S Beck Molecular Aspects of Medicine 34 (4), 849-862, 2013 | 68 | 2013 |
The dynamics of DNA methylation covariation patterns in carcinogenesis AE Teschendorff, X Liu, H Caren, SM Pollard, S Beck, M Widschwendter, ... PLoS computational biology 10 (7), e1003709, 2014 | 64 | 2014 |
Verification of genes differentially expressed in neuroblastoma tumours: a study of potential tumour suppressor genes K Thorell, A Bergman, H Carén, S Nilsson, P Kogner, T Martinsson, F Abel BMC medical genomics 2, 1-13, 2009 | 62 | 2009 |
MethPed: a DNA methylation classifier tool for the identification of pediatric brain tumor subtypes A Danielsson, S Nemes, M Tisell, B Lannering, C Nordborg, M Sabel, ... Clinical epigenetics 7, 1-9, 2015 | 55 | 2015 |