Fluorescence lifetime imaging microscopy: fundamentals and advances in instrumentation, analysis, and applications R Datta, TM Heaster, JT Sharick, AA Gillette, MC Skala Journal of biomedical optics 25 (7), 071203-071203, 2020 | 603 | 2020 |
Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models ML Schulte, A Fu, P Zhao, J Li, L Geng, ST Smith, J Kondo, RJ Coffey, ... Nature medicine 24 (2), 194-202, 2018 | 385 | 2018 |
Patient-derived cancer organoid cultures to predict sensitivity to chemotherapy and radiation CA Pasch, PF Favreau, AE Yueh, CP Babiarz, AA Gillette, JT Sharick, ... Clinical Cancer Research 25 (17), 5376-5387, 2019 | 191 | 2019 |
Protein-bound NAD(P)H Lifetime is Sensitive to Multiple Fates of Glucose Carbon JT Sharick, PF Favreau, AA Gillette, SM Sdao, MJ Merrins, MC Skala Scientific Reports 8 (1), 5456, 2018 | 112 | 2018 |
Metabolic heterogeneity in patient tumor-derived organoids by primary site and drug treatment JT Sharick, CM Walsh, CM Sprackling, CA Pasch, DL Pham, K Esbona, ... Frontiers in Oncology 10, 553, 2020 | 99 | 2020 |
Cellular Metabolic Heterogeneity In Vivo Is Recapitulated in Tumor Organoids JT Sharick, JJ Jeffery, MR Karim, CM Walsh, K Esbona, RS Cook, ... Neoplasia 21 (6), 615-626, 2019 | 64 | 2019 |
Temporal binning of time-correlated single photon counting data improves exponential decay fits and imaging speed AJ Walsh, JT Sharick, MC Skala, HT Beier Biomedical Optics Express 7 (4), 1385-1399, 2016 | 37 | 2016 |
Sample preparation strategies for high‐throughput mass spectrometry imaging of primary tumor organoids J Johnson, JT Sharick, MC Skala, L Li Journal of Mass Spectrometry 55 (4), e4452, 2020 | 30 | 2020 |
MEK activation modulates glycolysis and supports suppressive myeloid cells in TNBC DA Franklin, JT Sharick, PI Ericsson-Gonzalez, V Sanchez, PT Dean, ... JCI insight 5 (15), 2020 | 29 | 2020 |
Pten regulates collagen fibrillogenesis by fibroblasts through SPARC CE Jones, JT Sharick, SE Colbert, VC Shukla, JM Zent, MC Ostrowski, ... Plos one 16 (2), e0245653, 2021 | 10 | 2021 |
Fluorescence Lifetime Measurements of NAD(P)H in Live Cells and Tissue AJ Walsh, AT Shah, JT Sharick, MC Skala Advanced Time-Correlated Single Photon Counting Applications, 435-456, 2015 | 9 | 2015 |
Redox imaging and optical coherence tomography of the respiratory ciliated epithelium DA Gil, JT Sharick, S Mancha, UA Gamm, MA Choma, MC Skala Journal of Biomedical Optics 24 (1), 010501-010501, 2019 | 7 | 2019 |
A miniaturized screening platform to identify novel regulators of extracellular matrix alignment CE Jones, JT Sharick, ST Sizemore, E Cukierman, AM Strohecker, ... Cancer research communications 2 (11), 1471-1486, 2022 | 6 | 2022 |
Click chemistry functionalization of self-assembling peptide hydrogels JT Sharick, AJ Atieh, KJ Gooch, JL Leight Journal of biomedical materials research. Part A, 2022 | 5 | 2022 |
Imaging intratumoral metabolic heterogeneity AJ Walsh, JT Sharick, MC Skala Nature biomedical engineering 3 (5), 333-334, 2019 | 4 | 2019 |
Optical metabolic imaging of heterogeneous drug response in pancreatic cancer patient organoids JT Sharick, CM Walsh, CM Sprackling, CA Pasch, AA Parikh, ... bioRxiv, 542167, 2019 | 4 | 2019 |
Three dimensional models of dedifferentiated liposarcoma cell lines: scaffold-based and scaffold-free approaches S Tahara, FCC de Faria, P Sarchet, F Calore, J Sharick, JL Leight, ... Human Cell 36 (3), 1081-1089, 2023 | 1 | 2023 |
Protein-bound NAD (P) H lifetime is sensitive to multiple fates of glucose carbon (Conference Presentation) JT Sharick, PF Favreau, AA Gillette, SM Sdao, MJ Merrins, MC Skala Biophysics, Biology and Biophotonics III: the Crossroads 10504, 1050403, 2018 | 1 | 2018 |
Single-cell metabolism predicts drug response in patient-derived pancreatic cancer organoids (Conference Presentation) JT Sharick, AA Parikh, JK Johnson, L Li, CA Pasch, DA Deming, ... Multiphoton Microscopy in the Biomedical Sciences XVIII 10498, 1049809, 2018 | 1 | 2018 |
Optical metabolic imaging measures early drug response in an allograft murine breast cancer model (Conference Presentation) JT Sharick, RS Cook, MC Skala Diagnosis and Treatment of Diseases in the Breast and Reproductive System …, 2017 | 1 | 2017 |