Post-translational methylation of high mobility group box 1 (HMGB1) causes its cytoplasmic localization in neutrophils I Ito, J Fukazawa, M Yoshida Journal of Biological Chemistry 282 (22), 16336-16344, 2007 | 296 | 2007 |
Estrogen inhibits transforming growth factor β signaling by promoting Smad2/3 degradation I Ito, A Hanyu, M Wayama, N Goto, Y Katsuno, S Kawasaki, Y Nakajima, ... Journal of biological chemistry 285 (19), 14747-14755, 2010 | 178 | 2010 |
The ubiquitin ligase CHIP acts as an upstream regulator of oncogenic pathways M Kajiro, R Hirota, Y Nakajima, K Kawanowa, K So-Ma, I Ito, Y Yamaguchi, ... Nature cell biology 11 (3), 312-319, 2009 | 176 | 2009 |
A nonclassical vitamin D receptor pathway suppresses renal fibrosis I Ito, T Waku, M Aoki, R Abe, Y Nagai, T Watanabe, Y Nakajima, I Ohkido, ... The Journal of clinical investigation 123 (11), 4579-4594, 2013 | 160 | 2013 |
KLF4 suppresses estrogen-dependent breast cancer growth by inhibiting the transcriptional activity of ERα K Akaogi, Y Nakajima, I Ito, S Kawasaki, SH Oie, A Murayama, K Kimura, ... Oncogene 28 (32), 2894-2902, 2009 | 129 | 2009 |
Lupus antibodies to the HMGB1 chromosomal protein: epitope mapping and association with disease activity A Hayashi, H Nagafuchi, I Ito, K Hirota, M Yoshida, S Ozaki Modern rheumatology 19 (3), 283-292, 2009 | 54 | 2009 |
Identification and characterization of the direct interaction between methotrexate (MTX) and high-mobility group box 1 (HMGB1) protein Y Kuroiwa, Y Takakusagi, T Kusayanagi, K Kuramochi, T Imai, ... PloS one 8 (5), e63073, 2013 | 53 | 2013 |
Estrogen and antiestrogens alter breast cancer invasiveness by modulating the transforming growth factor‐β signaling pathway N Goto, H Hiyoshi, I Ito, M Tsuchiya, Y Nakajima, J Yanagisawa Cancer science 102 (8), 1501-1508, 2011 | 51 | 2011 |
M2b macrophage elimination and improved resistance of mice with chronic alcohol consumption to opportunistic infections H Ohama, A Asai, I Ito, S Suzuki, M Kobayashi, K Higuchi, F Suzuki The American Journal of Pathology 185 (2), 420-431, 2015 | 49 | 2015 |
M2b monocytes provoke bacterial pneumonia and gut bacteria–associated sepsis in alcoholics Y Tsuchimoto, A Asai, Y Tsuda, I Ito, T Nishiguchi, MC Garcia, S Suzuki, ... The Journal of Immunology 195 (11), 5169-5177, 2015 | 44 | 2015 |
The nucleolar protein Myb-binding protein 1A (MYBBP1A) enhances p53 tetramerization and acetylation in response to nucleolar disruption W Ono, Y Hayashi, W Yokoyama, T Kuroda, H Kishimoto, I Ito, K Kimura, ... Journal of Biological Chemistry 289 (8), 4928-4940, 2014 | 43 | 2014 |
Orosomucoid 1 drives opportunistic infections through the polarization of monocytes to the M2b phenotype K Nakamura, I Ito, M Kobayashi, DN Herndon, F Suzuki Cytokine 73 (1), 8-15, 2015 | 42 | 2015 |
M2b macrophage polarization accompanied with reduction of long noncoding RNA GAS5 I Ito, A Asai, S Suzuki, M Kobayashi, F Suzuki Biochemical and biophysical research communications 493 (1), 170-175, 2017 | 36 | 2017 |
Macrophage polarization and MRSA infection in burned mice T Nishiguchi, I Ito, JO Lee, S Suzuki, F Suzuki, M Kobayashi Immunology and cell biology 95 (2), 198-206, 2017 | 32 | 2017 |
Identification of a novel compound that suppresses breast cancer invasiveness by inhibiting transforming growth factor-β signaling via estrogen receptor α N Goto, H Hiyoshi, I Ito, K Iida, Y Nakajima, K Nagasawa, J Yanagisawa Journal of cancer 5 (5), 336, 2014 | 28 | 2014 |
Pathologic inflammation in malnutrition is driven by proinflammatory intestinal microbiota, large intestine barrier dysfunction, and translocation of bacterial lipopolysaccharide GT Patterson, EY Osorio, A Peniche, SM Dann, E Cordova, GA Preidis, ... Frontiers in immunology 13, 846155, 2022 | 27 | 2022 |
Survival of mice with gastrointestinal acute radiation syndrome through control of bacterial translocation F Suzuki, BD Loucas, I Ito, A Asai, S Suzuki, M Kobayashi The Journal of Immunology 201 (1), 77-86, 2018 | 22 | 2018 |
Structural basis for vitamin D receptor agonism by novel non-secosteroidal ligands L Asano, I Ito, N Kuwabara, T Waku, J Yanagisawa, H Miyachi, T Shimizu FEBS letters 587 (7), 957-963, 2013 | 20 | 2013 |
The Polarization of M2b Monocytes in Cultures of Burn Patient Peripheral CD14+ Cells Treated with a Selected Human CCL1 Antisense Oligodeoxynucleotide I Ito, KK Bhopale, T Nishiguchi, JO Lee, DN Herndon, S Suzuki, ... nucleic acid therapeutics 26 (5), 269-276, 2016 | 18 | 2016 |
Conformational difference in HMGB1 proteins of human neutrophils and lymphocytes revealed by epitope mapping of a monoclonal antibody I Ito, N Mitsuoka, J Sobajima, H Uesugi, S Ozaki, K Ohya, M Yoshida Journal of biochemistry 136 (2), 155-162, 2004 | 16 | 2004 |