CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids MM Ibrahim, F Porreca, J Lai, PJ Albrecht, FL Rice, A Khodorova, G Davar, ... Proceedings of the National Academy of Sciences 102 (8), 3093-3098, 2005 | 682 | 2005 |
Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS MM Ibrahim, H Deng, A Zvonok, DA Cockayne, J Kwan, HP Mata, ... Proceedings of the National Academy of Sciences 100 (18), 10529-10533, 2003 | 612 | 2003 |
Unmasking the tonic-aversive state in neuropathic pain T King, L Vera-Portocarrero, T Gutierrez, TW Vanderah, G Dussor, J Lai, ... Nature neuroscience 12 (11), 1364-1366, 2009 | 591 | 2009 |
CB2 cannabinoid receptor-mediated peripheral antinociception TP Malan Jr, MM Ibrahim, H Deng, Q Liu, HP Mata, T Vanderah, F Porreca, ... Pain 93 (3), 239-245, 2001 | 519 | 2001 |
AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2, 3-dihydrobenzo [b][1, 4] dioxin-6-yl) acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties NR Gavva, R Tamir, Y Qu, L Klionsky, TJ Zhang, D Immke, J Wang, D Zhu, ... Journal of Pharmacology and Experimental Therapeutics 313 (1), 474-484, 2005 | 446 | 2005 |
Molecular determinants of vanilloid sensitivity in TRPV1 NR Gavva, L Klionsky, Y Qu, L Shi, R Tamir, S Edenson, TJ Zhang, ... Journal of biological chemistry 279 (19), 20283-20295, 2004 | 430 | 2004 |
Distinct potassium channels on pain-sensing neurons MN Rasband, EW Park, TW Vanderah, J Lai, F Porreca, JS Trimmer Proceedings of the National Academy of Sciences 98 (23), 13373-13378, 2001 | 428 | 2001 |
Dynorphin promotes abnormal pain and spinal opioid antinociceptive tolerance TW Vanderah, LR Gardell, SE Burgess, M Ibrahim, A Dogrul, CM Zhong, ... Journal of Neuroscience 20 (18), 7074-7079, 2000 | 418 | 2000 |
Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance TW Vanderah, NMH Suenaga, MH Ossipov, TP Malan, J Lai, F Porreca Journal of Neuroscience 21 (1), 279-286, 2001 | 396 | 2001 |
Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not initiate, neuropathic pain SE Burgess, LR Gardell, MH Ossipov, TP Malan, TW Vanderah, J Lai, ... Journal of Neuroscience 22 (12), 5129-5136, 2002 | 394 | 2002 |
Peripheral mechanisms of pain and analgesia C Stein, JD Clark, U Oh, MR Vasko, GL Wilcox, AC Overland, ... Brain research reviews 60 (1), 90-113, 2009 | 374 | 2009 |
Regular exercise reverses sensory hypersensitivity in a rat neuropathic pain model: role of endogenous opioids NJ Stagg, HP Mata, MM Ibrahim, EJ Henriksen, F Porreca, TW Vanderah, ... The Journal of the American Society of Anesthesiologists 114 (4), 940-948, 2011 | 368 | 2011 |
Mechanisms of opioid-induced pain and antinociceptive tolerance: descending facilitation and spinal dynorphin TW Vanderah, MH Ossipov, J Lai, TP Malan Jr, F Porreca Pain 92 (1-2), 5-9, 2001 | 367 | 2001 |
Pronociceptive actions of dynorphin maintain chronic neuropathic pain Z Wang, LR Gardell, MH Ossipov, TW Vanderah, MB Brennan, ... Journal of Neuroscience 21 (5), 1779-1786, 2001 | 357 | 2001 |
Lack of antinociceptive cross-tolerance between [D-Pen2, D-Pen5] enkephalin and [D-Ala2] deltorphin II in mice: evidence for delta receptor subtypes. A Mattia, T Vanderah, HI Mosberg, F Porreca Journal of Pharmacology and Experimental Therapeutics 258 (2), 583-587, 1991 | 320 | 1991 |
Underlying mechanisms of pronociceptive consequences of prolonged morphine exposure MH Ossipov, J Lai, T King, TW Vanderah, F Porreca Peptide Science: Original Research on Biomolecules 80 (2‐3), 319-324, 2005 | 313 | 2005 |
Sustained morphine exposure induces a spinal dynorphin-dependent enhancement of excitatory transmitter release from primary afferent fibers LR Gardell, R Wang, SE Burgess, MH Ossipov, TW Vanderah, TP Malan, ... Journal of Neuroscience 22 (15), 6747-6755, 2002 | 313 | 2002 |
Inhibition of neuropathic pain by selective ablation of brainstem medullary cells expressing the μ-opioid receptor F Porreca, SE Burgess, LR Gardell, TW Vanderah, TP Malan, MH Ossipov, ... Journal of Neuroscience 21 (14), 5281-5288, 2001 | 305 | 2001 |
Inhibition of Inflammatory Hyperalgesia by Activation of Peripheral CB2Cannabinoid Receptors A Quartilho, HP Mata, MM Ibrahim, TW Vanderah, F Porreca, ... The Journal of the American Society of Anesthesiologists 99 (4), 955-960, 2003 | 303 | 2003 |
Preclinical assessment of candidate analgesic drugs: recent advances and future challenges SS Negus, TW Vanderah, MR Brandt, EJ Bilsky, L Becerra, D Borsook Journal of Pharmacology and Experimental Therapeutics 319 (2), 507-514, 2006 | 301 | 2006 |